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  3. FIBP 蛋白, Human

FIBP 蛋白, Human

目录号: HY-P72641
产品使用指南

FIBP 是酸性成纤维细胞生长因子 (aFGF) 的细胞内伴侣,介导 aFGF 的促有丝分裂作用,通过有丝分裂影响细胞类型并诱导形态变化和分化。该基因表达两种亚型,显示出潜在的功能多样性。FIBP 蛋白, Human 是重组的 FIBP 蛋白,由 E. coli 表达,不带标签。FIBP 蛋白, Human 全长 357 个氨基酸,分子量为 40-50 kDa。

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描述

FIBP is an intracellular chaperone of acidic fibroblast growth factor (aFGF) and mediates the mitogenic effects of aFGF, affecting cell types through mitosis and inducing morphological changes and differentiation. This gene expresses two isoforms, showing potential functional diversity. FIBP Protein, Human is the recombinant human-derived FIBP protein, expressed by E. coli , with tag free. The total length of FIBP Protein, Human is 357 a.a., with molecular weight of 40-50 kDa.

研究背景

FIBP 蛋白作为酸性成纤维细胞生长因子 (aFGF) 的细胞内结合伴侣发挥着关键作用,aFGF 是一种对各种细胞类型具有广泛影响的有丝分裂原,可刺激有丝分裂发生并诱导形态变化和分化。FIBP 与 aFGF 的选择性结合表明它可能参与介导细胞内 aFGF 的有丝分裂作用。该基因表现出编码不同亚型的两种转录变体,突出了其功能作用的潜在多样性。FIBP 表现出普遍存在的表达,在睾丸 (RPKM 27.1)、大脑 (RPKM 21.5) 和 25 个其他组织中检测到显着水平。它的广泛存在强调了它可能参与多个器官的不同细胞过程。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

O43427-2/NP_004205.2 (M1-D357)

基因 ID
蛋白结构
N-term
FIBP (M1-D357)
Accession # NP_004205.2
C-term
同用名
Acidic fibroblast growth factor intracellular-binding protein; FGF-1 intracellular-binding protein; FIBP
氨基酸序列

MTSELDIFVGNTTLIDEDVYRLWLDGYSVTDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQMDDMDMDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRFFLNQYSASVHSLDGFRHQALWDRYMGTLRGCLLRLYHD

分子量

40-50 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FIBP Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FIBP Protein, Human
目录号:
HY-P72641
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