FLT3LG 蛋白, Human (CHO)

FLT3LG Protein, Human (CHO) is a cytokine, which can promote the generation and differentiation of hematopoietic stem cells and their progenitor cells.

Fms相关酪氨酸激酶3配体是一种细胞因子，能够促进造血干细胞及其祖细胞的生成和分化。Fms相关酪氨酸激酶3配体的mRNA在某些组织中高表达，包括外周血单核细胞、心脏、胎盘、肺、脾和胸腺组织，在非造血组织中也有一定程度的表达，包括前列腺、睾丸、卵巢、肠道、肝脏、肾脏和骨骼肌^[1]。

1.The ED₅₀ is <1 ng/mL as measured by human AML5 cells, corresponding to a specific activity of >1 × 10⁶ units/mg.
2.Measured in a cell proliferation assay using HL-60 cells. The ED₅₀ for this effect is 0.9476 ng/mL, corresponding to a specific activity is 1.055×10⁶ units/mg.

Human

CHO

Tag Free

P49771-1 (T27-P185)

2323  [NCBI]

TQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTAPQPP

Approximately 18-22 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS or PBS, pH 7.4, 8% trehalose.

<0.2 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. Li F, et al. Fms-related tyrosine kinase 3 ligand promotes proliferation of placenta amnion and chorion mesenchymal stem cells in vitro. Mol Med Rep. 2014 Jul;10(1):322-8.  [Content Brief]