FOXM1 蛋白, Human (His, SUMO-Myc)

FOXM1 is an important transcription factor that controls cell cycle gene expression critical for DNA replication and mitosis, underscoring its critical role in cellular processes. In addition to cell proliferation, FOXM1 contributes to DNA break repair and DNA damage checkpoint responses. FOXM1 Protein, Human (His, SUMO-Myc) is the recombinant human-derived FOXM1 protein, expressed by E. coli , with N-10*His, C-Myc, N-SUMO labeled tag.

FOXM1 是一种重要的转录因子，控制着对 DNA 复制和有丝分裂至关重要的细胞周期基因的表达，强调了其在协调细胞过程中的关键作用。除了参与细胞增殖控制之外，FOXM1 还有助于 DNA 断裂修复，积极参与 DNA 损伤检查点反应。值得注意的是，FOXM1 促进 PHB2 的转录，强调其多样化的调节功能。此外，FOXM1 与 PINT87aa 相互作用，PINT87aa 是由长非编码 RNA LINC-PINT 的环状形式编码的产物，这种相互作用可以抑制 FOXM1 介导的 PHB2 转录，揭示细胞转录过程中复杂的调控层。

Human

E. coli

N-10*His;C-Myc;N-SUMO

Q08050-1 (E235-L327)

2305  [NCBI]

ERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPL

Approximately 31.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl,0.5 M NaCl, 6% Trehalose, pH 8.0

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.