Galactokinase/GALK1 蛋白, Human (His)

Galactokinase (GALK1) protein facilitates the transfer of a phosphate group from ATP to alpha-D-galactose, playing a pivotal role in the initial and committed step of galactose catabolism. Through this enzymatic activity, GALK1 initiates the metabolic pathway responsible for breaking down galactose, contributing to its utilization within cellular processes. Galactokinase/GALK1 Protein, Human (His) is the recombinant human-derived Galactokinase/GALK1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Galactokinase/GALK1 Protein, Human (His) is 392 a.a., with molecular weight of ~45.0 kDa.

半乳激酶 (GALK1) 是一种酶，通过催化磷酸基团从 ATP 转移到 α-D-半乳糖，在半乳糖分解代谢中发挥关键作用。这种酶活性代表半乳糖代谢途径中的第一个关键步骤，启动其转化为下游代谢物。GALK1 对半乳糖的磷酸化是半乳糖利用的关键步骤，并允许随后的酶促反应，导致半乳糖衍生的代谢物掺入各种细胞过程。了解 GALK1 的功能可以深入了解半乳糖代谢的调节及其在细胞能量产生和糖复合物合成中的重要性。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。

Human

E. coli

C-6*His

P51570 (M1-L392)

2584  [NCBI]

MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL

Approximately 47.0 kDa

Greater than 85% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 15% Trehalose, 10% Glycerol, 0.1% Tween80, 1mM TCEP, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.