Galectin-7/LGALS7 蛋白, Human

Galectin-7 (LGALS7), a protein with potential involvement in cell-cell and/or cell-matrix interactions crucial for normal growth control, serves as a pro-apoptotic factor. It functions intracellularly, playing a role upstream of JNK activation and cytochrome c release, thus contributing to apoptotic pathways. Galectin-7 exists as a monomer, highlighting its individual unit structure. Galectin-7/LGALS7 Protein, Human is the recombinant human-derived Galectin-7/LGALS7 protein, expressed by E. coli , with tag free. The total length of Galectin-7/LGALS7 Protein, Human is 136 a.a., with molecular weight of ~14.0 kDa.

Galectin-7，也称为 LGALS7，是一种可能参与正常生长控制所必需的关键细胞-细胞和/或细胞-基质相互作用的蛋白质。Galectin-7 作为一种促凋亡蛋白，在细胞内 JNK 激活和细胞色素 c 释放的上游发挥作用，表明其在凋亡途径中的作用。它作为单体存在，其参与细胞相互作用和细胞凋亡过程强调了其在调节细胞生长和存活中的重要性。了解 Galectin-7 的功能有助于深入了解控制正常细胞过程和细胞凋亡信号传导的复杂分子机制。

Measured in a cell proliferation assay using SH-SY5Y cells. The ED₅₀ for this effect is 0.2176 μg/mL, corresponding to a specific activity is 4.596×10³ units/mg.

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  Measured in a cell proliferation assay using SH-SY5Y cells. The ED₅₀ for this effect is 0.2176 μg/mL , corresponding to a specific activity is 4.596×10³ units/mg.

Human

E. coli

Tag Free

P47929 (M1-F136)

3963  [NCBI]/653499  [NCBI]

MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF

Approximately 14.0 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 1 mM EDTA, 5% Trehalose, pH 8.0 or 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.