2. Gene
  3. LGALS7 - galectin 7 Gene

LGALS7 - galectin 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：半乳糖凝集素 7

种属: Homo sapiens

同用名: GAL7; LGALS7A

基因 ID: 3963 | 基因类型: protein coding

关于 LGALS7

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,770,968-38,773,517 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 328 orthologues and 16 paralogues. Restricted expression toward skin (RPKM 300.6).

功能概要

半乳糖凝集素是β-半乳糖苷结合蛋白家族，参与调节细胞-细胞和细胞-基质相互作用。差异和原位杂交研究表明，这种凝集素在角质形成细胞中特异性表达，主要存在于复层鳞状上皮细胞中。该基因的副本 (GeneID:653499) 被发现与 19 号染色体相邻，但位于相反的链上。[RefSeq 提供，2008 年 7 月]

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]

LGALS7 基因产物(1)

mRNA Protein Name
NM_002307.4 NP_002298.1 galectin-7

LGALS7 蛋白结构

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (7 - 134)

  • 0
  • 100
  • 136 a.a.
蛋白主名 其他名称

galectin-7

lectin, galactoside-binding, soluble, 7

LGALS7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LGALS7 P47929 TGM5 Homo sapiens O43548
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 TGM5 Homo sapiens O43548
Y2H Array
32296183
种属内
LGALS7 P47929 YAF2 Homo sapiens Q8IY57-5
Validated Y2H
32296183
种属内
LGALS7 P47929 YAF2 Homo sapiens Q8IY57-5
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 YAF2 Homo sapiens Q8IY57-5
Y2H Array
32296183
种属内
LGALS7 P47929 LSM2 Homo sapiens Q9Y333
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 LSM2 Homo sapiens Q9Y333
Validated Y2H
32296183
种属内
LGALS7 P47929 LSM2 Homo sapiens Q9Y333
Y2H Array
32296183
种属内
LGALS7 P47929 SSBP1 Homo sapiens Q04837
Validated Y2H
32296183
种属内
LGALS7 P47929 SSBP1 Homo sapiens Q04837
Y2H Array
32296183
种属内
LGALS7 P47929 SSBP1 Homo sapiens Q04837
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 HSPA6 Homo sapiens P17066
Y2H Array
32296183
种属内
LGALS7 P47929 HSPA6 Homo sapiens P17066
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 TAB1 Homo sapiens Q15750
Y2H Prey Pooling
32296183
种属内
LGALS7 P47929 TAB1 Homo sapiens Q15750
Validated Y2H
32296183
种属内
LGALS7 P47929 TAB1 Homo sapiens Q15750
Y2H Array
32296183
种属内
LGALS7 P47929 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
种属内
LGALS7 P47929 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
种属内
LGALS7 P47929 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 LGALS7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70358 Galectin-7/LGALS7 Protein, Human P47929 (M1-F136) ≥95%
HY-P73071 Galectin-7/LGALS7 Protein, Human (GST) P47929 (S2-F136) ≥95%
HY-P700080AF Animal-Free Galectin-7/LGALS7 Protein, Human (His) P47929 (S2-F136) ≥95%

关联疾病

疾病名称 别名
Esophageal Basaloid Squamous Cell Carcinoma

Basaloid Squamous Carcinoma Of Esophagus

Esophageal Basaloid Carcinoma
Galactosemia I

Galactosemia

Galt Deficiency

Classic Galactosemia

Galactose-1-Phosphate Uridylyltransferase Deficiency

Galactose-1-Phosphate Uridyltransferase Deficiency

GALAC1

Galactosemia, Classic

Galactosemia Type 1

Galactosemias

Classical Galactosemia

Galactosaemia

Galactose Intolerance

Epimerase Deficiency Galactosemia

Galactokinase Deficiency Disease

Galactose Epimerase Deficiency

Galactose-1-Phosphate Uridyl-Transferase Deficiency Disease

Gale Deficiency

Galk Deficiency

Udp-Galactose-4-Epimerase Deficiency Disease

Utp Hexose-1-Phosphate Uridylyltransferase Deficiency

Galactosemia 1

Galactosemia, Duarte Variant

Deficiency Of Galactokinase

Udpglucose 4-Epimerase Deficiency Disease

Classical Galactosaemia

Galput Deficiency - [Galactose-4-Phosphate Uridyltransferase] Deficiency

Classic Galactosaemia

Deficiency Of Hexose-1-Phosphate Uridylyltransferase

Deficiency Of Udpglucose-Hexose-1-Phosphate Uridylyltransferase

Deficiency Of Galactose-1-Phosphate Uridylyltransferase

Galactose-1-Phosphate Uridyl Transferase Deficiency

Transferase Deficiency Galactosemia

Deficiency Of Uridyl Transferase

Deficiency Of Utp-Hexose-1-Phosphate Uridylyltransferase

Utp-Hexose-1-Phosphate Uridyltransferase Deficiency
Bladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Bladder

Epidermoid Carcinoma Of The Urinary Bladder

Carcinoma Squamous Cell Bladder
Amyloid Tumor

Amyloid Neoplasm

Amyloid Tumour
Uterus Carcinoma In Situ
Cervix Uteri Carcinoma In Situ

Carcinoma In Situ Of Cervix

Carcinoma In Situ Of Uterine Cervix

Cervical Intraepithelial Neoplasia

Carcinoma Of Cervix Stage 0

Cervical Intraepithelial Neoplasia Grade Iii With Severe Dysplasia

Cervix Ca In Situ

Cin Iii

Cin Iii - Carcinoma In Situ Of Cervix

Cin Iii - Severe Dyskaryosis

Severe Dysplasia Of Cervix

Severe Dysplasia Of The Cervix Uteri

Squamous Intraepithelial Neoplasia, Grade Iii

Cervix Intraepithelial Neoplasia Grade 3 Ajcc V7
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07607 LGALS7 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07608 LGALS7B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LGALS7 RGD RGD:61951
Mus musculus LGALS7 MGD MGI:1316742
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