DDIT4L - DNA damage inducible transcript 4 like Gene

中文名称：DNA 损伤诱导转录物 4 样

种属: Homo sapiens

同用名: REDD2; Rtp801L

基因 ID: 115265 | 基因类型: protein coding

关于 DDIT4L

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:100,185,870-100,190,468 (from NCBI)

This gene has 3 transcripts (splice variants), 184 orthologues and 1 paralogue. Biased expression in prostate (RPKM 12.6), kidney (RPKM 5.8) and 10 other tissues.

功能概要

预计参与信号转导的负调控。预计位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DDIT4L 基因产物(1)

mRNA	Protein	Name
NM_145244.4	NP_660287.1	DNA damage-inducible transcript 4-like protein

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DDIT4L 蛋白结构

RTP801_C

0
100
193 a.a.

蛋白主名

其他名称

DNA damage-inducible transcript 4-like protein

HIF-1 responsive protein RTP801-like

DDIT4L 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	DDIT4L	Q96D03	CATIP	Homo sapiens	Q7Z7H3	Y2H Array	32296183
种属内	DDIT4L	Q96D03	TRIM74	Homo sapiens	Q86UV6-2	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	TRIM74	Homo sapiens	Q86UV6-2	Y2H Array	32296183
种属内	DDIT4L	Q96D03	MORF4L1	Homo sapiens	Q9UBU8-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NUDT22	Homo sapiens	Q9BRQ3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CABP5	Homo sapiens	Q9NP86	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NGB	Homo sapiens	Q9NPG2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	ARHGEF3	Homo sapiens	Q9NR81	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NUDT11	Homo sapiens	Q96G61	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TARS2	Homo sapiens	Q9BW92	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CHMP1A	Homo sapiens	Q9HD42	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SCOC	Homo sapiens	Q9UIL1-3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NXT2	Homo sapiens	Q9NPJ8-3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	MEMO1	Homo sapiens	Q9Y316	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PUF60	Homo sapiens	Q9UHX1-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CARD9	Homo sapiens	Q9H257-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	EMILIN1	Homo sapiens	Q9Y6C2-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NEK6	Homo sapiens	Q9HC98-4	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CTNNA3	Homo sapiens	Q9UI47-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	BANF2	Homo sapiens	Q9H503-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NDRG4	Homo sapiens	Q9ULP0-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CPNE7	Homo sapiens	Q9UBL6-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	XPNPEP1	Homo sapiens	Q9NQW7-3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PITX2	Homo sapiens	Q99697-2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TFPT	Homo sapiens	P0C1Z6	BFG-2H	27107012
种属内	DDIT4L	Q96D03	TFPT	Homo sapiens	P0C1Z6	Validated Y2H	27107012
种属内	DDIT4L	Q96D03	NHLRC4	Homo sapiens	P0CG21	Y2H Array	32296183
种属内	DDIT4L	Q96D03	NHLRC4	Homo sapiens	P0CG21	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	BCL2L14	Homo sapiens	Q9BZR8	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PLAA	Homo sapiens	Q9Y263	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TCP11L1	Homo sapiens	Q9NUJ3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PPIL1	Homo sapiens	Q9Y3C6	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PRPF18	Homo sapiens	Q99633	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	WHRN	Homo sapiens	Q9P202	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Y2H Array	25416956
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Y2H Array	32296183
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Y2H Array	31515488
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Validated Y2H	25416956
种属内	DDIT4L	Q96D03	LSM7	Homo sapiens	Q9UK45	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	VBP1	Homo sapiens	P61758	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	VBP1	Homo sapiens	P61758	Y2H Array	32296183
种属内	DDIT4L	Q96D03	EXOSC5	Homo sapiens	Q9NQT4	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	EXOSC1	Homo sapiens	Q9Y3B2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	LSM5	Homo sapiens	Q9Y4Y9	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SEPTIN5	Homo sapiens	Q99719	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	ACY3	Homo sapiens	Q96HD9	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TSSK3	Homo sapiens	Q96PN8	MAPPIT	32296183
种属内	DDIT4L	Q96D03	TSSK3	Homo sapiens	Q96PN8	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PARVG	Homo sapiens	Q9HBI0	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	MORF4L2	Homo sapiens	Q15014	Y2H Array	25416956
种属内	DDIT4L	Q96D03	MORF4L2	Homo sapiens	Q15014	Y2H Prey Pooling	25416956
种属内	DDIT4L	Q96D03	IL36RN	Homo sapiens	Q9UBH0	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SH3BGRL3	Homo sapiens	Q9H299	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PBK	Homo sapiens	Q96KB5	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PSMB9	Homo sapiens	P28065	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	PSMB9	Homo sapiens	P28065	Y2H Array	32296183
种属内	DDIT4L	Q96D03	MIEN1	Homo sapiens	Q9BRT3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SNRPG	Homo sapiens	P62308	MAPPIT	32296183
种属内	DDIT4L	Q96D03	SNRPG	Homo sapiens	P62308	Validated Y2H	32814053
种属内	DDIT4L	Q96D03	SNRPG	Homo sapiens	P62308	Y2H Array	32814053
种属内	DDIT4L	Q96D03	SNRPG	Homo sapiens	P62308	Y2H Pooling	32814053
种属内	DDIT4L	Q96D03	NIBAN1	Homo sapiens	Q9BZQ8	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	MYLIP	Homo sapiens	Q8WY64	Y2H Array	32296183
种属内	DDIT4L	Q96D03	MYLIP	Homo sapiens	Q8WY64	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	MYG1	Homo sapiens	Q9HB07	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	DCTPP1	Homo sapiens	Q9H773	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	DUSP23	Homo sapiens	Q9BVJ7	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	C14orf119	Homo sapiens	Q9NWQ9	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	MAPRE3	Homo sapiens	Q9UPY8	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SEPTIN3	Homo sapiens	Q9UH03	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	HSPB7	Homo sapiens	Q9UBY9	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CALCOCO2	Homo sapiens	Q13137	Y2H Prey Pooling	25416956
种属内	DDIT4L	Q96D03	CALCOCO2	Homo sapiens	Q13137	Y2H Array	25416956
种属内	DDIT4L	Q96D03	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	C19orf25	Homo sapiens	Q9UFG5	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TCF19	Homo sapiens	Q9Y242	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CEP19	Homo sapiens	Q96LK0	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NME7	Homo sapiens	Q9Y5B8	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CLK3	Homo sapiens	P49761	Y2H Prey Pooling	32296183
种属内	DDIT4L	Q96D03	CLK3	Homo sapiens	P49761	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	CLK3	Homo sapiens	P49761	Y2H Array	32296183
种属内	DDIT4L	Q96D03	STAC3	Homo sapiens	Q96MF2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TOLLIP	Homo sapiens	Q9H0E2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NAA10	Homo sapiens	P41227	MAPPIT	32296183
种属内	DDIT4L	Q96D03	RPRD1B	Homo sapiens	Q9NQG5	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	PLSCR4	Homo sapiens	Q9NRQ2	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	SEC22A	Homo sapiens	Q96IW7	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TBC1D22B	Homo sapiens	Q9NU19	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	TBC1D22B	Homo sapiens	Q9NU19	Y2H Array	32296183
种属内	DDIT4L	Q96D03	MLX	Homo sapiens	Q9UH92-3	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	LRATD2	Homo sapiens	Q96KN1	Validated Y2H	32296183
种属内	DDIT4L	Q96D03	NDEL1	Homo sapiens	Q9GZM8	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Brain Germinoma

Intracranial Germinoma

Germinoma Of The Brain

Lung Pleomorphic Carcinoma

Zika Fever

Zika Virus Infection	Zika Virus Disease
Zika Virus	Zika Virus Fever
Mosquito-Borne Viral Fever, Zika

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03616	DDIT4L Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	DDIT4L	VGNC	VGNC:39838
Felis catus	DDIT4L	VGNC	VGNC:61391
Rattus norvegicus	DDIT4L	RGD	RGD:2322961
Bos taurus	DDIT4L	VGNC	VGNC:27949
Macaca mulatta	DDIT4L	VGNC	VGNC:106566
Mus musculus	DDIT4L	MGD	MGI:1920534

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