1. Gene
  2. DDIT4L - DNA damage inducible transcript 4 like Gene

DDIT4L - DNA damage inducible transcript 4 like Gene

中文名称:DNA 损伤诱导转录物 4 样

种属: Homo sapiens

同用名: REDD2; Rtp801L

基因 ID: 115265 | 基因类型: protein coding

关于 DDIT4L

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:100,185,870-100,190,468 (from NCBI)

This gene has 3 transcripts (splice variants), 184 orthologues and 1 paralogue. Biased expression in prostate (RPKM 12.6), kidney (RPKM 5.8) and 10 other tissues.

功能概要

预计参与信号转导的负调控。预计位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DDIT4L 基因产物(1)

mRNA Protein Name
NM_145244.4 NP_660287.1 DNA damage-inducible transcript 4-like protein
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DDIT4L 蛋白结构

RTP801_C

RTP801_C: RTP801 C-terminal region (65 - 183)

  • 0
  • 100
  • 193 a.a.
蛋白主名 其他名称

DNA damage-inducible transcript 4-like protein

HIF-1 responsive protein RTP801-like

关联疾病

疾病名称 别名
Brain Germinoma

Intracranial Germinoma

Germinoma Of The Brain

Lung Pleomorphic Carcinoma
Zika Fever

Zika Virus Infection

Zika Virus Disease

Zika Virus

Zika Virus Fever

Mosquito-Borne Viral Fever, Zika

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris DDIT4L VGNC VGNC:39838
Felis catus DDIT4L VGNC VGNC:61391
Rattus norvegicus DDIT4L RGD RGD:2322961
Bos taurus DDIT4L VGNC VGNC:27949
Macaca mulatta DDIT4L VGNC VGNC:106566
Mus musculus DDIT4L MGD MGI:1920534