1. Gene
  2. DUSP23 - dual specificity phosphatase 23 Gene

DUSP23 - dual specificity phosphatase 23 Gene

中文名称:双特异性磷酸酶 23

种属: Homo sapiens

同用名: VHZ; LDP3; MOSP; LDP-3; DUSP25

基因 ID: 54935 | 基因类型: protein coding

关于 DUSP23

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,780,962-159,782,543 (from NCBI)

This gene has 3 transcripts (splice variants) and 181 orthologues. Ubiquitous expression in kidney (RPKM 18.6), liver (RPKM 13.3) and 25 other tissues.

功能概要

启用蛋白酪氨酸/丝氨酸/苏氨酸磷酸酶活性。参与去磷酸化。位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables protein tyrosine/serine/threonine Phosphatase activity. Involved in dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DUSP23 基因产物(3)

mRNA Protein Name
NM_001319658.2 NP_001306587.1 dual specificity protein phosphatase 23
NM_001319659.2 NP_001306588.1 dual specificity protein phosphatase 23
NM_017823.5 NP_060293.2 dual specificity protein phosphatase 23

DUSP23 蛋白结构

DSPc

DSPc: Dual specificity phosphatase, catalytic domain (30 - 145)

  • 0
  • 100
  • 150 a.a.
蛋白主名 其他名称

dual specificity protein phosphatase 23

VH1-like member Z

DUSP23 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Validated Y2H
32296183
Intra DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 MRNIP Homo sapiens Q6NTE8
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 MRNIP Homo sapiens Q6NTE8
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Validated Y2H
25910212
Intra DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Bait-Prey Pool
25910212
Intra DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Array
25910212
Intra DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 PSMB8 Homo sapiens P28062-2
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 PSMB8 Homo sapiens P28062-2
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Validated Y2H
32296183
Intra DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 UBA3 Homo sapiens Q8TBC4
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 UBA3 Homo sapiens Q8TBC4
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 NIF3L1 Homo sapiens Q9GZT8
Validated Y2H
25416956
Intra DUSP23 Q9BVJ7 NIF3L1 Homo sapiens Q9GZT8
Y2H Prey Pooling
25416956
Intra DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Validated Y2H
32296183
Intra DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Y2H Array
32296183
Intra DUSP23 Q9BVJ7 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra DUSP23 Q9BVJ7 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
West Nile Fever
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DUSP23 VGNC VGNC:71880
Mus musculus DUSP23 MGD MGI:1915690
Felis catus DUSP23 VGNC VGNC:107869
Rattus norvegicus DUSP23 RGD RGD:1309202
Bos taurus DUSP23 VGNC VGNC:28257