ASB6 - ankyrin repeat and SOCS box containing 6 Gene

中文名称：含锚蛋白重复和 SOCS 盒 6

种属: Homo sapiens

关于 ASB6

功能概要

由该基因编码的蛋白质属于锚蛋白重复蛋白家族，该家族与其他四个蛋白质家族一起包含一个 C 端 SOCS 盒基序。越来越多的证据表明，与 F-box 类似，SOCS box 充当特定底物结合域和包含 E3 泛素蛋白连接酶大家族的更通用蛋白质之间的桥梁。已经确定了该基因的可变剪接转录物变体。[RefSeq 提供，2011 年 1 月]

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four Other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]