MYG1 - MYG1 exonuclease Gene

中文名称：MYG1 核酸外切酶

种属: Homo sapiens

同用名: MYG; Gamm1; MST024; MSTP024; C12orf10

基因 ID: 60314 | 基因类型: protein coding

关于 MYG1

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,299,695-53,307,177 (from NCBI)

This gene has 10 transcripts (splice variants) and 204 orthologues. Broad expression in testis (RPKM 46.7), ovary (RPKM 22.5) and 25 other tissues.

功能概要

预测启用核酸酶活性。预测参与核酸磷酸二酯键的水解。预计在运动探索行为的上游或内部行动。位于线粒体和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to act upstream of or within locomotory exploration behavior. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MYG1 基因产物(1)

mRNA	Protein	Name
NM_021640.4	NP_067653.4	MYG1 exonuclease precursor

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in mitochondrion	IDA IDA: 通过直接分析推断	19014353	GOA
located in nucleus	IDA IDA: 通过直接分析推断	19014353	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MYG1 蛋白结构

UPF0160

0
100
200
300
376 a.a.

蛋白主名

其他名称

MYG1 exonuclease

UPF0160 protein MYG1, mitochondrial

MYG1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	MYG1	Q9HB07	FAM9B	Homo sapiens	Q8IZU0	Y2H Array	31515488
种属内	MYG1	Q9HB07	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
种属内	MYG1	Q9HB07	DCDC2	Homo sapiens	Q9UHG0	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	DCDC2	Homo sapiens	Q9UHG0	Validated Y2H	32296183
种属内	MYG1	Q9HB07	DCDC2	Homo sapiens	Q9UHG0	Y2H Array	32296183
种属内	MYG1	Q9HB07	PELO	Homo sapiens	Q9BRX2	Validated Y2H	32814053
种属内	MYG1	Q9HB07	PELO	Homo sapiens	Q9BRX2	Y2H Array	32814053
种属内	MYG1	Q9HB07	PELO	Homo sapiens	Q9BRX2	Y2H Pooling	32814053
种属内	MYG1	Q9HB07	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	32296183
种属内	MYG1	Q9HB07	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	32296183
种属内	MYG1	Q9HB07	AP1B1	Homo sapiens	Q10567-3	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	AP1B1	Homo sapiens	Q10567-3	Y2H Array	32296183
种属内	MYG1	Q9HB07	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32296183
种属内	MYG1	Q9HB07	SYNGR1	Homo sapiens	O43759-2	Validated Y2H	32296183
种属内	MYG1	Q9HB07	SYNGR1	Homo sapiens	O43759-2	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	SYNGR1	Homo sapiens	O43759-2	Y2H Array	32296183
种属内	MYG1	Q9HB07	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Array	32296183
种属内	MYG1	Q9HB07	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	DESI2	Homo sapiens	Q9BSY9	Y2H Array	32296183
种属内	MYG1	Q9HB07	DESI2	Homo sapiens	Q9BSY9	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	REEP6	Homo sapiens	Q96HR9-2	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	REEP6	Homo sapiens	Q96HR9-2	Y2H Array	32296183
种属内	MYG1	Q9HB07	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Array	32296183
种属内	MYG1	Q9HB07	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	TIMM17B	Homo sapiens	O60830	Y2H Array	32296183
种属内	MYG1	Q9HB07	TIMM17B	Homo sapiens	O60830	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	CMTM5	Homo sapiens	Q96DZ9	Y2H Array	25416956
种属内	MYG1	Q9HB07	CMTM5	Homo sapiens	Q96DZ9	Validated Y2H	25416956
种属内	MYG1	Q9HB07	CPLX2	Homo sapiens	Q6PUV4	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	CPLX2	Homo sapiens	Q6PUV4	Y2H Array	32296183
种属内	MYG1	Q9HB07	YIF1A	Homo sapiens	O95070	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	YIF1A	Homo sapiens	O95070	Y2H Array	32296183
种属内	MYG1	Q9HB07	METTL9	Homo sapiens	Q9H1A3	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	METTL9	Homo sapiens	Q9H1A3	Y2H Array	32296183
种属内	MYG1	Q9HB07	SFT2D1	Homo sapiens	Q8WV19	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	SFT2D1	Homo sapiens	Q8WV19	Y2H Array	32296183
种属内	MYG1	Q9HB07	MTNAP1	Homo sapiens	Q9BSJ5	Validated Y2H	32814053
种属内	MYG1	Q9HB07	MTNAP1	Homo sapiens	Q9BSJ5	Y2H Array	32814053
种属内	MYG1	Q9HB07	MTNAP1	Homo sapiens	Q9BSJ5	Y2H Pooling	32814053
种属内	MYG1	Q9HB07	EEF1G	Homo sapiens	P26641	Y2H Array	32814053
种属内	MYG1	Q9HB07	EEF1G	Homo sapiens	P26641	Validated Y2H	32814053
种属内	MYG1	Q9HB07	EEF1G	Homo sapiens	P26641	Y2H Pooling	32814053
种属内	MYG1	Q9HB07	APOA5	Homo sapiens	Q6Q788	Y2H Array	32296183
种属内	MYG1	Q9HB07	APOA5	Homo sapiens	Q6Q788	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	SLC17A9	Homo sapiens	Q9BYT1	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	SLC17A9	Homo sapiens	Q9BYT1	Y2H Array	32296183
种属内	MYG1	Q9HB07	ARL6IP1	Homo sapiens	Q15041	Y2H Array	25416956
种属内	MYG1	Q9HB07	ARL6IP1	Homo sapiens	Q15041	Y2H Array	32296183
种属内	MYG1	Q9HB07	ARL6IP1	Homo sapiens	Q15041	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	DCAF10	Homo sapiens	Q5QP82	Anti Tag CoIP	33961781
种属内	MYG1	Q9HB07	PLIN3	Homo sapiens	O60664	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	PLIN3	Homo sapiens	O60664	Y2H Array	32296183
种属内	MYG1	Q9HB07	MAN1C1	Homo sapiens	Q9NR34	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	MAN1C1	Homo sapiens	Q9NR34	Y2H Array	32296183
种属内	MYG1	Q9HB07	MAN1C1	Homo sapiens	Q9NR34	Validated Y2H	32296183
种属内	MYG1	Q9HB07	AGTRAP	Homo sapiens	Q6RW13	Y2H Array	25416956
种属内	MYG1	Q9HB07	AGTRAP	Homo sapiens	Q6RW13	Y2H Prey Pooling	25416956
种属内	MYG1	Q9HB07	AGTRAP	Homo sapiens	Q6RW13	Validated Y2H	25416956
种属内	MYG1	Q9HB07	RBM11	Homo sapiens	P57052	Y2H Array	32814053
种属内	MYG1	Q9HB07	RBM11	Homo sapiens	P57052	Y2H Pooling	32814053
种属内	MYG1	Q9HB07	RBM11	Homo sapiens	P57052	Validated Y2H	32814053
种属内	MYG1	Q9HB07	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
种属内	MYG1	Q9HB07	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	32296183
种属内	MYG1	Q9HB07	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
种属内	MYG1	Q9HB07	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
种属内	MYG1	Q9HB07	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	BSND	Homo sapiens	Q8WZ55	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	BSND	Homo sapiens	Q8WZ55	Y2H Array	32296183
种属内	MYG1	Q9HB07	SYP	Homo sapiens	P08247	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	SYP	Homo sapiens	P08247	Y2H Array	32296183
种属内	MYG1	Q9HB07	ROM1	Homo sapiens	Q03395	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	ROM1	Homo sapiens	Q03395	Y2H Array	32296183
种属内	MYG1	Q9HB07	MAL2	Homo sapiens	Q969L2	Y2H Prey Pooling	32296183
种属内	MYG1	Q9HB07	MAL2	Homo sapiens	Q969L2	Y2H Array	32296183
种属内	MYG1	Q9HB07	TMEM239	Homo sapiens	Q8WW34	Y2H Array	25416956
种属内	MYG1	Q9HB07	TMEM239	Homo sapiens	Q8WW34	Y2H Prey Pooling	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Nemaline Myopathy 4

Cap Myopathy 2	NEM4
Nemaline Myopathy 4, Autosomal Dominant	Nemaline Myopathy, Type 4
CAPM2	Cap Disease
Cap Myopathy Tpm2-Related	Tpm2-Related Nemaline Myopathy
Tpm2-Related Cap Myopathy	Myopathy, Nemaline, Type 4
Cap Myopathy

Dracunculiasis

Guinea Worm Disease	Dracontiasis
Dracunculosis	Infection By Dracunculus Medinensis
Gwd	Guinea Worm Infection
Parasitic Infection Caused By Dracunculus Medinensis	Medina Worm Disease
Medinensis	Medina Worm Infestation
Dracunculus Medinensis Infestation	Guinea Worm Infestation

Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1

Vitiligo	VAMAS1
Slev1	Vtlg
Systemic Lupus Erythematosus, Vitiligo-Related	Vitiligo-Associated Multiple Autoimmune Disease 1
Systemic Lupus Erythematosus Vitiligo-Related

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS08894	MYG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	MYG1	VGNC	VGNC:49228
Mus musculus	MYG1	MGD	MGI:1929864
Macaca mulatta	MYG1	VGNC	VGNC:70338
Bos taurus	MYG1	VGNC	VGNC:49159
Rattus norvegicus	MYG1	RGD	RGD:1359237

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