2. Gene
  3. EEF1G - eukaryotic translation elongation factor 1 gamma Gene

EEF1G - eukaryotic translation elongation factor 1 gamma Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：真核翻译延伸因子 1 伽玛

种属: Homo sapiens

同用名: EF1G; GIG35

基因 ID: 1937 | 基因类型: protein coding

关于 EEF1G

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,559,596-62,573,891 (from NCBI)

This gene has 4 transcripts (splice variants), 235 orthologues and 14 paralogues. Ubiquitous expression in ovary (RPKM 1189.4), lymph node (RPKM 694.2) and 25 other tissues.

功能概要

该基因编码延伸因子 1 复合物的一个亚基，负责将氨酰 tRNA 酶促递送至核糖体。该亚基包含一个 N 末端谷胱甘肽转移酶结构域，它可能参与调节含有该延伸因子和氨酰-tRNA 合成酶的多亚基复合物的组装。[RefSeq 提供，2008 年 7 月]

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

EEF1G 基因产物(1)

mRNA Protein Name
NM_001404.5 NP_001395.1 elongation factor 1-gamma
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10908348 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to virus IEP
IEP: 通过表达模式推断
16548883 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
8743958 GOA
colocalizes with endoplasmic reticulum IDA
IDA: 通过直接分析推断
8743958 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EEF1G 蛋白结构

GST_N

GST_N: Glutathione S-transferase, N-terminal domain (3 - 80)

GST_C

GST_C: Glutathione S-transferase, C-terminal domain (108 - 198)

EF1G

EF1G: Elongation factor 1 gamma, conserved domain (275 - 381)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 437 a.a.
蛋白主名 其他名称

elongation factor 1-gamma

EF-1-gamma

EEF1G 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra EEF1G P26641 UQCRC1 Homo sapiens P31930
Validated Y2H
32814053
Intra EEF1G P26641 UQCRC1 Homo sapiens P31930
Y2H Array
32814053
Intra EEF1G P26641 UQCRC1 Homo sapiens P31930
Y2H Pooling
32814053
Intra EEF1G P26641 EEF1B2 Homo sapiens P24534
Anti Tag CoIP
33961781
Intra EEF1G P26641 EEF1B2 Homo sapiens P24534
Anti Tag CoIP
28514442
Intra EEF1G P26641 EEF1B2 Homo sapiens P24534
Anti Tag CoIP
35271311
Intra EEF1G P26641 EEF1B2 Homo sapiens P24534
Y2H Pooling
16169070
Intra EEF1G P26641 EEF1D Homo sapiens P29692
Anti Tag CoIP
35271311
Intra EEF1G P26641 EEF1D Homo sapiens P29692
Crosslink
30021884
Intra EEF1G P26641 EEF1D Homo sapiens P29692
Y2H Pooling
16169070
Intra EEF1G P26641 EEF1D Homo sapiens P29692
Anti Tag CoIP
33961781
Intra EEF1G P26641 EEF1D Homo sapiens P29692-2
Validated Y2H
32814053
Intra EEF1G P26641 EEF1D Homo sapiens P29692-2
Y2H Pooling
32814053
Intra EEF1G P26641 EEF1D Homo sapiens P29692-2
Y2H Array
32814053
Intra EEF1G P26641 EEF1D Homo sapiens P29692-2
Anti Tag CoIP
28514442
Intra EEF1G P26641 TRIM63 Homo sapiens Q969Q1
Y2H
18157088
Intra EEF1G P26641 TRIM63 Homo sapiens Q969Q1
Pull Down
18157088
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pontiac Fever
Podoconiosis

PDCOS

Podoconiosis, Susceptibility To

Nonfilarial Elephantiasis Of Lower Legs

Nonfilarial Elephantiasis Of Lower Legs, Susceptibility To

Endemic Nonfilarial Elephantiasis

Endemic Nonfilarial Elephantiasis, Susceptibility To

Lymphostatic Verrucosis

Lymphostatic Verrucosis, Susceptibility To

Elephantiasis

Endemic Non-Filarial Elephantiasis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04179 EEF1G Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus EEF1G MGD MGI:1914410
Rattus norvegicus EEF1G RGD RGD:1302939
Bos taurus EEF1G VGNC VGNC:28334
Felis catus EEF1G VGNC VGNC:81197
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