1. Gene
  2. BCL2L14 - BCL2 like 14 Gene

BCL2L14 - BCL2 like 14 Gene

中文名称:BCL2 样 14

种属: Homo sapiens

同用名: BCLG

基因 ID: 79370 | 基因类型: protein coding

关于 BCL2L14

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:12,049,861-12,099,695 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele, 165 orthologues and 1 paralogue. Biased expression in testis (RPKM 9.1), duodenum (RPKM 7.7) and 10 other tissues.

功能概要

该基因编码的蛋白质属于 BCL2 蛋白家族。 BCL2 家族成员形成异二聚体或同二聚体,并作为参与多种细胞活动的抗或促凋亡调节剂。该基因的过度表达已被证明可诱导细胞凋亡。已经报道了该基因的编码两种不同亚型的三种选择性剪接的转录物变体。[RefSeq 提供,2009 年 5 月]

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce Apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]

BCL2L14 基因产物(5)

mRNA Protein Name
NM_001370268.1 NP_001357197.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_001370269.1 NP_001357198.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_030766.2 NP_110393.1 apoptosis facilitator Bcl-2-like protein 14 isoform 2
NM_138722.2 NP_620048.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_138723.2 NP_620049.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
蛋白主名 其他名称

apoptosis facilitator Bcl-2-like protein 14

BCL2-like 14 (apoptosis facilitator)

BCL2L14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
BCL2L14 Q9BZR8 MELK Homo sapiens Q14680 17280616
种属内
BCL2L14 Q9BZR8 MELK Homo sapiens Q14680 17280616
种属内
BCL2L14 Q9BZR8 TEPSIN Homo sapiens Q96N21 32296183
种属内
BCL2L14 Q9BZR8 TEPSIN Homo sapiens Q96N21 32296183
种属内
BCL2L14 Q9BZR8 LGALS3BP Homo sapiens Q08380 30833792
种属内
BCL2L14 Q9BZR8 DDIT4L Homo sapiens Q96D03 32296183
种属内
BCL2L14 Q9BZR8 DDIT4L Homo sapiens Q96D03 32296183
种属内
BCL2L14 Q9BZR8 PICK1 Homo sapiens Q9NRD5 32296183
种属内
BCL2L14 Q9BZR8 PICK1 Homo sapiens Q9NRD5 32296183
种属内
BCL2L14 Q9BZR8 PICK1 Homo sapiens Q9NRD5 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

BCL2L14 抗体

目录号 产品名 应用 反应物种
HY-P82995 Bcl2 L14 Antibody (YA2740) WB, ICC/IF, IP Human, Mouse, Rat

直系同源

种属 基因名 来源 基因 ID
Mus musculus BCL2L14 MGD MGI:1914063
Canis familiaris BCL2L14 VGNC VGNC:38410
Bos taurus BCL2L14 VGNC VGNC:26448
Rattus norvegicus BCL2L14 RGD RGD:1562777
Felis catus BCL2L14 VGNC VGNC:60085
Macaca mulatta BCL2L14 VGNC VGNC:70083