2. Gene
  3. SNRPG - small nuclear ribonucleoprotein polypeptide G Gene

SNRPG - small nuclear ribonucleoprotein polypeptide G Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：小核核糖核蛋白多肽 G

种属: Homo sapiens

同用名: SMG; Sm-G

基因 ID: 6637 | 基因类型: protein coding

关于 SNRPG

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:70,281,362-70,293,740 (from NCBI)

This gene has 9 transcripts (splice variants), 181 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 14.7), appendix (RPKM 13.1) and 25 other tissues.

功能概要

该基因编码的蛋白质是 U1、U2、U4 和 U5 小核核糖核蛋白复合物 (剪接体的前体) 的组成部分。编码的蛋白质也可能是 U7 小核核糖核蛋白复合物的一部分，它参与组蛋白转录物 3' 端的加工。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供，2015 年 11 月]

The protein encoded by this gene is a component of the U1, U2, U4, and U5 small nuclear ribonucleoprotein complexes, precursors of the spliceosome. The encoded protein may also be a part of the U7 small nuclear ribonucleoprotein complex, which participates in the processing of the 3' end of histone transcripts. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

SNRPG 基因产物(7)

mRNA Protein Name
NM_001317165.2 NP_001304094.1 small nuclear ribonucleoprotein G isoform b
NM_001317166.2 NP_001304095.1 small nuclear ribonucleoprotein G isoform c
NM_001317167.1 NP_001304096.1 small nuclear ribonucleoprotein G isoform d
NM_001317168.1 NP_001304097.1 small nuclear ribonucleoprotein G isoform e
NM_001317169.2 NP_001304098.1 small nuclear ribonucleoprotein G isoform e
NM_001317171.2 NP_001304100.1 small nuclear ribonucleoprotein G isoform f
NM_003096.4 NP_003087.1 small nuclear ribonucleoprotein G isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9417867 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
28076346 GOA
involved in spliceosomal snRNP assembly IDA
IDA: 通过直接分析推断
18984161 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SMN-Sm protein complex IDA
IDA: 通过直接分析推断
18984161 GOA
part of U1 snRNP IDA
IDA: 通过直接分析推断
21113136 GOA
part of U1 snRNP IPI
IPI: 通过物理相互作用推断
33677607 GOA
part of U12-type spliceosomal complex IDA
IDA: 通过直接分析推断
15146077 GOA
part of U2-type catalytic step 2 spliceosome IDA
IDA: 通过直接分析推断
28076346 GOA
part of U2-type precatalytic spliceosome IDA
IDA: 通过直接分析推断
28781166 GOA
part of U2-type spliceosomal complex IDA
IDA: 通过直接分析推断
32494006 GOA
part of U4 snRNP IDA
IDA: 通过直接分析推断
21516107 GOA
part of U4/U6 x U5 tri-snRNP complex IDA
IDA: 通过直接分析推断
26912367 GOA
part of U4/U6 x U5 tri-snRNP complex IPI
IPI: 通过物理相互作用推断
30975767 GOA
part of U7 snRNP IDA
IDA: 通过直接分析推断
11574479 GOA
part of catalytic step 2 spliceosome IDA
IDA: 通过直接分析推断
11991638 GOA
located in cytosol IDA
IDA: 通过直接分析推断
18984161 GOA
part of methylosome IDA
IDA: 通过直接分析推断
18984161 GOA
located in nucleus IDA
IDA: 通过直接分析推断
28076346 GOA
part of spliceosomal complex IPI
IPI: 通过物理相互作用推断
33677607 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SNRPG 蛋白结构

LSM

LSM: LSM domain (8 - 70)

  • 0
  • 76 a.a.
蛋白主名 其他名称

small nuclear ribonucleoprotein G

sm protein G

SNRPG 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SNRPG P62308 NFATC2IP Homo sapiens Q8NCF5-2
Y2H Pooling
32814053
Intra SNRPG P62308 NFATC2IP Homo sapiens Q8NCF5-2
Validated Y2H
32814053
Intra SNRPG P62308 NFATC2IP Homo sapiens Q8NCF5-2
Y2H Array
32814053
Intra SNRPG P62308 SF3A2 Homo sapiens Q15428
Affinity Chrom
17332742
Intra SNRPG P62308 SF3A2 Homo sapiens Q15428
Anti Tag CoIP
33961781
Intra SNRPG P62308 SNRPE Homo sapiens P62304
Y2H Array
32296183
Intra SNRPG P62308 SNRPE Homo sapiens P62304
Anti Tag CoIP
33961781
Intra SNRPG P62308 SNRPE Homo sapiens P62304
Y2H Prey Pooling
32296183
Intra SNRPG P62308 SNRPE Homo sapiens P62304
Crosslink
30021884
Intra SNRPG P62308 SNRPF Homo sapiens P62306
Anti Tag CoIP
33961781
Intra SNRPG P62308 SNRPF Homo sapiens P62306
Y2H
22365833
Intra SNRPG P62308 TFF2 Homo sapiens Q03403
Validated Y2H
32814053
Intra SNRPG P62308 TFF2 Homo sapiens Q03403
Y2H Array
32814053
Intra SNRPG P62308 TFF2 Homo sapiens Q03403
Y2H Pooling
32814053
Intra SNRPG P62308 TACC1 Homo sapiens O75410-1
Pull Down
12165861
Intra SNRPG P62308 TACC1 Homo sapiens O75410-1
Y2H
12165861
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Y2H Prey Pooling
25416956
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Anti Tag CoIP
33961781
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Y2H Prey Pooling
32296183
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Validated Y2H
25416956
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Y2H Array
25416956
Intra SNRPG P62308 CLNS1A Homo sapiens P54105
Y2H Array
32296183
Intra SNRPG P62308 TCL1B Homo sapiens O95988
Y2H Prey Pooling
32296183
Intra SNRPG P62308 TCL1B Homo sapiens O95988
Y2H Array
32296183
Intra SNRPG P62308 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
32296183
Intra SNRPG P62308 FHL3 Homo sapiens Q13643
Validated Y2H
32296183
Intra SNRPG P62308 FHL3 Homo sapiens Q13643
Y2H Array
32296183
Intra SNRPG P62308 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
25416956
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Y2H Pooling
16189514
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Validated Y2H
25416956
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
25416956
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Y2H Array
25416956
Intra SNRPG P62308 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra SNRPG P62308 GEMIN6 Homo sapiens Q8WXD5
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spinal Muscular Atrophy

Sma

5q Sma

Proximal Sma

Sma-Associated Sma

Spinal Amyotrophies

Spinal Amyotrophy

Spinal Muscle Degeneration

Spinal Muscle Wasting

Muscular Atrophy Spinal

Atrophy, Muscular, Spinal

Hereditary Motor Neuronopathy

Progressive Muscular Atrophy

Sma - [Spinal Muscular Atrophy]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13510 SNRPG Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SNRPG VGNC VGNC:54547
Mus musculus SNRPG MGD MGI:1915261
Rattus norvegicus SNRPG RGD RGD:1584713
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z