SNRPF - small nuclear ribonucleoprotein polypeptide F Gene

中文名称：小核核糖核蛋白多肽 F

种属: Homo sapiens

同用名: SMF; Sm-F; snRNP-F

基因 ID: 6636 | 基因类型: protein coding

关于 SNRPF

Cytogenetic location: 12q23.1 Genomic coordinates (GRCh38): 12:95,858,952-95,866,140 (from NCBI)

This gene has 5 transcripts (splice variants), 204 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 26.2), colon (RPKM 24.6) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与剪接体 snRNP 组装。位于细胞质和细胞核中。几种细胞成分的一部分，包括甲基体；核;和 pICln-Sm 蛋白复合物。鼻咽癌的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in spliceosomal snRNP assembly. Located in cytosol and nucleus. Part of several cellular components, including methylosome; nucleus; and pICln-Sm protein complex. Biomarker of nasopharynx carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

SNRPF 基因产物(2)

mRNA	Protein	Name
NM_001394209.1	NP_001381138.1	small nuclear ribonucleoprotein F isoform 2
NM_003095.5	NP_003086.1	small nuclear ribonucleoprotein F isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA binding	IMP IMP: 通过突变表型推断	7744013	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	9417867	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in RNA splicing	IMP IMP: 通过突变表型推断	7744013	GOA
involved in mRNA splicing, via spliceosome	IDA IDA: 通过直接分析推断	28076346	GOA
involved in spliceosomal snRNP assembly	IDA IDA: 通过直接分析推断	18984161	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of SMN-Sm protein complex	IDA IDA: 通过直接分析推断	18984161	GOA
part of U1 snRNP	IDA IDA: 通过直接分析推断	21113136	GOA
part of U1 snRNP	IPI IPI: 通过物理相互作用推断	33677607	GOA
part of U12-type spliceosomal complex	IDA IDA: 通过直接分析推断	15146077	GOA
part of U2-type catalytic step 2 spliceosome	IDA IDA: 通过直接分析推断	28076346	GOA
part of U2-type precatalytic spliceosome	IDA IDA: 通过直接分析推断	28781166	GOA
part of U2-type spliceosomal complex	IDA IDA: 通过直接分析推断	32494006	GOA
part of U4 snRNP	IDA IDA: 通过直接分析推断	21516107	GOA
part of U4/U6 x U5 tri-snRNP complex	IDA IDA: 通过直接分析推断	26912367	GOA
part of U4/U6 x U5 tri-snRNP complex	IPI IPI: 通过物理相互作用推断	30975767	GOA
part of U7 snRNP	IDA IDA: 通过直接分析推断	11574479	GOA
part of catalytic step 2 spliceosome	IDA IDA: 通过直接分析推断	11991638	GOA
located in cytosol	IDA IDA: 通过直接分析推断	18984161	GOA
part of methylosome	IDA IDA: 通过直接分析推断	18984161	GOA
located in nucleus	IDA IDA: 通过直接分析推断	28076346	GOA
part of pICln-Sm protein complex	IDA IDA: 通过直接分析推断	18984161	GOA
part of small nuclear ribonucleoprotein complex	IDA IDA: 通过直接分析推断	11991638	GOA
part of spliceosomal complex	IDA IDA: 通过直接分析推断	7744013	GOA
part of spliceosomal complex	IPI IPI: 通过物理相互作用推断	33677607	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SNRPF 蛋白结构

LSM

0
86 a.a.

蛋白主名

其他名称

small nuclear ribonucleoprotein F

sm protein F

SNRPF 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422-7	Y2H Array	32296183
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422-7	Validated Y2H	32296183
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422-7	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	MEOX2	Homo sapiens	Q6FHY5	Validated Y2H	32296183
Intra	SNRPF	P62306	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	SNRPF	P62306	SF3A2	Homo sapiens	Q15428	Anti Tag CoIP	28514442
Intra	SNRPF	P62306	SF3A2	Homo sapiens	Q15428	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	SF3A2	Homo sapiens	Q15428	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	OSBPL2	Homo sapiens	Q9H1P3	Validated Y2H	32296183
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Y2H Array	32296183
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Y2H	9417867
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Y2H	22365833
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Anti Tag CoIP	28514442
Intra	SNRPF	P62306	SNRPD2	Homo sapiens	P62316	Validated Y2H	32296183
Intra	SNRPF	P62306	SNRPE	Homo sapiens	P62304	Y2H Array	32296183
Intra	SNRPF	P62306	SNRPE	Homo sapiens	P62304	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	SNRPE	Homo sapiens	P62304	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	LSM3	Homo sapiens	P62310	Validated Y2H	32296183
Intra	SNRPF	P62306	LSM3	Homo sapiens	P62310	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	LSM7	Homo sapiens	Q9UK45	Validated Y2H	32296183
Intra	SNRPF	P62306	LSM7	Homo sapiens	Q9UK45	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	LSM7	Homo sapiens	Q9UK45	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	LSM7	Homo sapiens	Q9UK45	Y2H Array	32296183
Intra	SNRPF	P62306	LSM5	Homo sapiens	Q9Y4Y9	MAPPIT	25416956
Intra	SNRPF	P62306	LSM5	Homo sapiens	Q9Y4Y9	Y2H Prey Pooling	25416956
Intra	SNRPF	P62306	LSM5	Homo sapiens	Q9Y4Y9	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	LSM5	Homo sapiens	Q9Y4Y9	Validated Y2H	32296183
Intra	SNRPF	P62306	LSM5	Homo sapiens	Q9Y4Y9	Y2H Array	25416956
Intra	SNRPF	P62306	LSM6	Homo sapiens	P62312	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	LSM6	Homo sapiens	P62312	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	GEMIN2	Homo sapiens	O14893	Y2H Array	32296183
Intra	SNRPF	P62306	GEMIN2	Homo sapiens	O14893	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	GEMIN2	Homo sapiens	O14893	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	GEMIN2	Homo sapiens	O14893	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	CLNS1A	Homo sapiens	P54105	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	CLNS1A	Homo sapiens	P54105	Anti Tag CoIP	28514442
Intra	SNRPF	P62306	CLNS1A	Homo sapiens	P54105	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	25416956
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422	Validated Y2H	25416956
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422	Y2H Array	25416956
Intra	SNRPF	P62306	IKZF1	Homo sapiens	Q13422	Y2H Prey Pooling	25416956
Intra	SNRPF	P62306	HOMER3	Homo sapiens	Q9NSC5	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	HOMER3	Homo sapiens	Q9NSC5	Validated Y2H	32296183
Intra	SNRPF	P62306	HOMER3	Homo sapiens	Q9NSC5	Y2H Array	32296183
Intra	SNRPF	P62306	GEMIN6	Homo sapiens	Q8WXD5	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	GEMIN6	Homo sapiens	Q8WXD5	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	GEMIN6	Homo sapiens	Q8WXD5	Anti Tag CoIP	28514442
Intra	SNRPF	P62306	SNRPA1	Homo sapiens	P09661	Y2H	22365833
Intra	SNRPF	P62306	SNRPA1	Homo sapiens	P09661	Anti Tag CoIP	35271311
Intra	SNRPF	P62306	SNRPA1	Homo sapiens	P09661	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	SNRPA1	Homo sapiens	P09661	Anti Tag CoIP	28514442
Intra	SNRPF	P62306	COIL	Homo sapiens	P38432	Anti Tag CoIP	33961781
Intra	SNRPF	P62306	COIL	Homo sapiens	P38432	Y2H Array	32296183
Intra	SNRPF	P62306	COIL	Homo sapiens	P38432	Y2H Prey Pooling	25416956
Intra	SNRPF	P62306	COIL	Homo sapiens	P38432	Y2H Prey Pooling	32296183
Intra	SNRPF	P62306	COIL	Homo sapiens	P38432	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Spinal Muscular Atrophy

Sma	5q Sma
Proximal Sma	Sma-Associated Sma
Spinal Amyotrophies	Spinal Amyotrophy
Spinal Muscle Degeneration	Spinal Muscle Wasting
Muscular Atrophy Spinal	Atrophy, Muscular, Spinal
Hereditary Motor Neuronopathy	Progressive Muscular Atrophy
Sma - [Spinal Muscular Atrophy]

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13509	SNRPF Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	SNRPF	MGD	MGI:1917128
Rattus norvegicus	SNRPF	RGD	RGD:1588229
Bos taurus	SNRPF	VGNC	VGNC:35081

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SNRPF - small nuclear ribonucleoprotein polypeptide F Gene

关于 SNRPF

功能概要

SNRPF 基因产物(2)

SNRPF 蛋白结构

SNRPF 蛋白互作信息

关联疾病

直系同源

热门区域

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SNRPF - small nuclear ribonucleoprotein polypeptide F Gene

关于 SNRPF

功能概要

SNRPF 基因产物(2)

SNRPF 蛋白结构

SNRPF 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z