LSM5 - LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated Gene

中文名称：LSM5 同系物、U6 小核 RNA 和 mRNA 降解相关

种属: Homo sapiens

同用名: YER146W

关于 LSM5

功能概要

基于与 Sm 蛋白家族的序列同源性，在多种生物体中鉴定出 Sm 样蛋白 (参见 SNRPD2；MIM 601061) 。 Sm 样蛋白包含 Sm 序列基序，该基序由 2 个区域组成，该区域由折叠成环的可变长度接头隔开。 Sm 样蛋白被认为形成了存在于 tri-snRNP 颗粒中的稳定异聚体，这对于 pre-mRNA 剪接很重要。[OMIM 提供，2004 年 4 月]

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]