2. Gene
  3. TCF19 - transcription factor 19 Gene

TCF19 - transcription factor 19 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转录因子 19

种属: Homo sapiens

同用名: SC1; TCF-19

基因 ID: 6941 | 基因类型: protein coding

关于 TCF19

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,158,589-31,164,215 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele and 189 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), appendix (RPKM 5.7) and 25 other tissues.

功能概要

该基因编码的蛋白质含有 PHD 型锌指结构域，可能作为转录因子发挥作用。所编码的蛋白在胰腺β细胞的增殖和凋亡中起作用。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 1 月]

This gene encodes a protein that contains a PHD-type zinc finger domain and likely functions as a transcription factor. The encoded protein plays a role proliferation and Apoptosis of pancreatic beta cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

TCF19 基因产物(3)

mRNA Protein Name
NM_001077511.2 NP_001070979.1 transcription factor 19
NM_001318908.2 NP_001305837.1 transcription factor 19
NM_007109.3 NP_009040.2 transcription factor 19
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TCF19 蛋白结构

FHA

FHA: FHA domain (36 - 105)

PHD

PHD: PHD-finger (296 - 341)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
蛋白主名 其他名称

transcription factor 19

transcription factor SC1

TCF19 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TCF19 Q9Y242 ZGPAT Homo sapiens Q8N5A5-2
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 ZGPAT Homo sapiens Q8N5A5-2
Y2H Array
32296183
种属内
TCF19 Q9Y242 NFKBID Homo sapiens Q8NI38
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 NFKBID Homo sapiens Q8NI38
Y2H Array
32296183
种属内
TCF19 Q9Y242 NOXA1 Homo sapiens Q86UR1-2
Y2H Array
32296183
种属内
TCF19 Q9Y242 NOXA1 Homo sapiens Q86UR1-2
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 RHOH Homo sapiens Q15669
Y2H Array
32296183
种属内
TCF19 Q9Y242 RHOH Homo sapiens Q15669
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 ZNF474 Homo sapiens Q6S9Z5
Y2H Array
32296183
种属内
TCF19 Q9Y242 ZNF474 Homo sapiens Q6S9Z5
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
种属内
TCF19 Q9Y242 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
种属内
TCF19 Q9Y242 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
种属内
TCF19 Q9Y242 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
种属内
TCF19 Q9Y242 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
种属内
TCF19 Q9Y242 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 HOXA1 Homo sapiens P49639
Y2H Array
32296183
种属内
TCF19 Q9Y242 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
种属内
TCF19 Q9Y242 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
种属内
TCF19 Q9Y242 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
种属内
TCF19 Q9Y242 E2F6 Homo sapiens O75461
Anti Tag CoIP
28514442
种属内
TCF19 Q9Y242 E2F6 Homo sapiens O75461
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Psoriasis 8

PSORS8

Psoriasis Susceptibility 8

Psoriasis 8, Susceptibility To
Psoriasis 9

PSORS9

Psoriasis 9, Susceptibility To

Psoriasis Susceptibility 9
Psoriasis 7

PSORS7

Psoriasis 7, Susceptibility To

Psoriasis Susceptibility 7

Psoriasis

Psoriasis Vulgaris

Pv
Peeling Skin Syndrome

Deciduous Skin

Familial Continuous Skin Peeling Syndrome

Idiopathic Deciduous Skin

Keratosis Exfoliativa Congenita

Pss

Peeling Skin Disease

Skin Peeling Syndrome

Familial Continuous Skin Peeling

Keratolysis Exfoliativa Congenita

Exfoliation Syndrome

Keratolysis Exfoliativa
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14301 TCF19 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TCF19 RGD RGD:1302974
Macaca mulatta TCF19 VGNC VGNC:83493
Felis catus TCF19 VGNC VGNC:66022
Canis familiaris TCF19 VGNC VGNC:47191
Bos taurus TCF19 VGNC VGNC:35688
Mus musculus TCF19 MGD MGI:103180
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