GOLGA2 - golgin A2 Gene

中文名称：高金 A2

种属: Homo sapiens

同用名: GM130

关于 GOLGA2

功能概要

参与分泌途径中蛋白质和脂质的糖基化和转运的高尔基体由一系列堆叠的池 (扁平膜囊) 组成。高尔基体和微管之间的相互作用被认为对于高尔基体在有丝分裂过程中断裂后的重组很重要。该基因编码一种 golgins，这是一个定位于高尔基体的蛋白质家族。这种编码的蛋白质已被假定在高尔基池的堆积和水泡运输中发挥作用。已经描述了该基因的几种可变剪接的转录本变体，但尚未确定这些变体的全长性质。[RefSeq 提供，2010 年 2 月]

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]