1. Gene
  2. ARL4A - ADP ribosylation factor like GTPase 4A Gene

ARL4A - ADP ribosylation factor like GTPase 4A Gene

中文名称:ADP 核糖基化因子样 GTPase 4A

种属: Homo sapiens

同用名: ARL4

基因 ID: 10124 | 基因类型: protein coding

关于 ARL4A

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:12,686,903-12,690,958 (from NCBI)

This gene has 7 transcripts (splice variants), 268 orthologues and 30 paralogues. Broad expression in testis (RPKM 32.8), bone marrow (RPKM 17.5) and 24 other tissues.

功能概要

ADP-核糖基化因子样 4A 是 GTP 结合蛋白的 ADP-核糖基化因子家族的成员。 ARL4A 与 ARL4C 和 ARL4D 相似,每个都有核定位信号和异常高的鸟嘌呤核苷酸交换率。 ARL4A 位于核和核外细胞区室中。已发现该基因编码相同蛋白质的多个转录变体。[RefSeq 提供,2008 年 7 月]

ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ARL4A 基因产物(4)

mRNA Protein Name
NM_001037164.3 NP_001032241.1 ADP-ribosylation factor-like protein 4A
NM_001195396.2 NP_001182325.1 ADP-ribosylation factor-like protein 4A
NM_005738.5 NP_005729.1 ADP-ribosylation factor-like protein 4A
NM_212460.4 NP_997625.1 ADP-ribosylation factor-like protein 4A

ARL4A 蛋白结构

Arf

Arf: ADP-ribosylation factor family (9 - 186)

  • 0
  • 100
  • 200 a.a.
蛋白主名 其他名称

ADP-ribosylation factor-like protein 4A

ADP-ribosylation factor-like 4

ARL4A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ARL4A P40617 CCDC102B Homo sapiens Q68D86
Y2H Array
25416956
种属内
ARL4A P40617 CCDC102B Homo sapiens Q68D86
Y2H Prey Pooling
25416956
种属内
ARL4A P40617 CCDC102B Homo sapiens Q68D86
Validated Y2H
25416956
种属内
ARL4A P40617 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
种属内
ARL4A P40617 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
种属内
ARL4A P40617 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
种属内
ARL4A P40617 POF1B Homo sapiens Q8WVV4-1
Y2H Prey Pooling
32296183
种属内
ARL4A P40617 POF1B Homo sapiens Q8WVV4-1
Validated Y2H
32296183
种属内
ARL4A P40617 POF1B Homo sapiens Q8WVV4-1
Y2H Array
32296183
种属内
ARL4A P40617 CCDC57 Homo sapiens Q2TAC2
Y2H Prey Pooling
25416956
种属内
ARL4A P40617 CCDC57 Homo sapiens Q2TAC2
Validated Y2H
25416956
种属内
ARL4A P40617 SPATC1L Homo sapiens Q9H0A9
Y2H Prey Pooling
25416956
种属内
ARL4A P40617 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
种属内
ARL4A P40617 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
种属内
ARL4A P40617 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
种属内
ARL4A P40617 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
种属内
ARL4A P40617 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
种属内
ARL4A P40617 KRT19 Homo sapiens P08727
Y2H Array
32296183
种属内
ARL4A P40617 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
种属内
ARL4A P40617 EVI5 Homo sapiens O60447
Y2H Prey Pooling
32296183
种属内
ARL4A P40617 EVI5 Homo sapiens O60447
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ARL4A VGNC VGNC:38112
Macaca mulatta ARL4A VGNC VGNC:84745
Felis catus ARL4A VGNC VGNC:69347
Rattus norvegicus ARL4A RGD RGD:2152
Bos taurus ARL4A VGNC VGNC:26144
Mus musculus ARL4A MGD MGI:99437