1. Gene
  2. MTFR2 - mitochondrial fission regulator 2 Gene

MTFR2 - mitochondrial fission regulator 2 Gene

中文名称:线粒体裂变调节因子 2

种属: Homo sapiens

同用名: DUFD1; FAM54A

基因 ID: 113115 | 基因类型: protein coding

关于 MTFR2

This gene has 7 transcripts (splice variants), 190 orthologues and 2 paralogues. Biased expression in testis (RPKM 2.0), bone marrow (RPKM 1.8) and 12 other tissues.

功能概要

预测参与有氧呼吸和线粒体分裂。预测在线粒体中活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MTFR2 基因产物(3)

mRNA Protein Name
NM_001099286.3 NP_001092756.1 mitochondrial fission regulator 2 isoform a
NM_001318738.2 NP_001305667.1 mitochondrial fission regulator 2 isoform b
NM_138419.5 NP_612428.2 mitochondrial fission regulator 2 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MTFR2 蛋白结构

Mito_fiss_reg

Mito_fiss_reg: Mitochondrial fission regulator (23 - 286)

  • 0
  • 100
  • 200
  • 300
  • 385 a.a.
蛋白主名 其他名称

mitochondrial fission regulator 2

DUF729 domain-containing protein 1

MTFR2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MTFR2 Q6P444 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra MTFR2 Q6P444 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
25416956
Intra MTFR2 Q6P444 ALAS1 Homo sapiens P13196
Validated Y2H
25416956
Intra MTFR2 Q6P444 ALAS1 Homo sapiens P13196
Y2H Array
25416956
Intra MTFR2 Q6P444 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra MTFR2 Q6P444 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
25416956
Intra MTFR2 Q6P444 TRIM23 Homo sapiens P36406
Validated Y2H
25416956
Intra MTFR2 Q6P444 MAGEA12 Homo sapiens P43365
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Suppurative Periapical Periodontitis

Periapical Abscess

Apical Abscess

Suppurative Apical Periodontitis

Dentoalveolar Abscess

Dental Abscess With Sinus

Dentoalveolar Abscess With Sinus

Dental Sinus

Periapical Abscess Fistula

Apical Tooth Abscess

Apex Abscess

Dental Abscess Nos

Infection Of Tooth Nos

Abscess Of Tooth

Dental Infection Nos

Lung Acinar Adenocarcinoma

Acinar Adenocarcinoma Of The Lung

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus MTFR2 VGNC VGNC:82491
Macaca mulatta MTFR2 VGNC VGNC:74999
Mus musculus MTFR2 MGD MGI:1919054
Bos taurus MTFR2 VGNC VGNC:31728
Rattus norvegicus MTFR2 RGD RGD:6494892
Canis familiaris MTFR2 VGNC VGNC:43470