MAGEA12 - MAGE family member A12 Gene

中文名称：MAGE 家族成员 A12

种属: Homo sapiens

同用名: CT1.12; MAGE12

基因 ID: 4111 | 基因类型: protein coding

关于 MAGEA12

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:152,733,757-152,737,669 (from NCBI)

This gene has 3 transcripts (splice variants), 459 orthologues and 37 paralogues. Restricted expression toward testis (RPKM 1.8).

功能概要

该基因与聚集在 X 染色体上的其他几个基因密切相关。这些基因可能在肿瘤中过度表达。已经鉴定出编码相同蛋白质的多个可变剪接变体。[RefSeq 提供，2014 年 6 月]

This gene is closely related to several other genes clustered on chromosome X. These genes may be overexpressed in tumors. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq, Jun 2014]

MAGEA12 基因产物(3)

mRNA	Protein	Name
NM_001166386.3	NP_001159858.1	melanoma-associated antigen 12
NM_001166387.4	NP_001159859.1	melanoma-associated antigen 12
NM_005367.7	NP_005358.2	melanoma-associated antigen 12

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MAGEA12 蛋白结构

MAGE_N

MAGE

0
100
200
314 a.a.

蛋白主名

其他名称

melanoma-associated antigen 12

MAGE12F antigen

MAGEA12 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	MAGEA12	P43365	NANOS2	Homo sapiens	P60321	Validated Y2H	32296183
Intra	MAGEA12	P43365	NANOS2	Homo sapiens	P60321	Y2H Array	25416956
Intra	MAGEA12	P43365	NANOS2	Homo sapiens	P60321	Y2H Array	31515488
Intra	MAGEA12	P43365	FASTKD3	Homo sapiens	Q14CZ7	Validated Y2H	25416956
Intra	MAGEA12	P43365	MTFR2	Homo sapiens	Q6P444	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	MTFR2	Homo sapiens	Q6P444	Y2H Array	25416956
Intra	MAGEA12	P43365	POLL	Homo sapiens	Q9UGP5-2	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	POLL	Homo sapiens	Q9UGP5-2	Validated Y2H	32296183
Intra	MAGEA12	P43365	POLL	Homo sapiens	Q9UGP5-2	Validated Y2H	25416956
Intra	MAGEA12	P43365	POLL	Homo sapiens	Q9UGP5-2	Y2H Array	25416956
Intra	MAGEA12	P43365	POU6F2	Homo sapiens	P78424	Validated Y2H	32296183
Intra	MAGEA12	P43365	TBC1D19	Homo sapiens	Q8N5T2	Y2H Array	25416956
Intra	MAGEA12	P43365	TBC1D19	Homo sapiens	Q8N5T2	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	TCP11L1	Homo sapiens	Q9NUJ3	Validated Y2H	32296183
Intra	MAGEA12	P43365	MTFR1L	Homo sapiens	Q9H019	Validated Y2H	25416956
Intra	MAGEA12	P43365	ZNF33B	Homo sapiens	Q06732	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	CLIP4	Homo sapiens	Q8N3C7	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	CLIP4	Homo sapiens	Q8N3C7	Validated Y2H	25416956
Intra	MAGEA12	P43365	CLIP4	Homo sapiens	Q8N3C7	Validated Y2H	32296183
Intra	MAGEA12	P43365	CLIP4	Homo sapiens	Q8N3C7	Y2H Array	25416956
Intra	MAGEA12	P43365	C16orf87	Homo sapiens	Q6PH81	Validated Y2H	32296183
Intra	MAGEA12	P43365	C16orf87	Homo sapiens	Q6PH81	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	C16orf87	Homo sapiens	Q6PH81	Validated Y2H	25416956
Intra	MAGEA12	P43365	KANSL1	Homo sapiens	Q7Z3B3	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	KANSL1	Homo sapiens	Q7Z3B3	Validated Y2H	25416956
Intra	MAGEA12	P43365	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	MAGEA12	P43365	HK2	Homo sapiens	P52789	Validated Y2H	25416956
Intra	MAGEA12	P43365	HK2	Homo sapiens	P52789	Y2H Array	25416956
Intra	MAGEA12	P43365	ABI3	Homo sapiens	Q9P2A4	Y2H Array	25416956
Intra	MAGEA12	P43365	FNDC11	Homo sapiens	Q9BVV2	Y2H Prey Pooling	25416956
Intra	MAGEA12	P43365	FNDC11	Homo sapiens	Q9BVV2	Validated Y2H	25416956
Intra	MAGEA12	P43365	FNDC11	Homo sapiens	Q9BVV2	Validated Y2H	32296183
Intra	MAGEA12	P43365	NPPA	Homo sapiens	P01160	Y2H Array	25416956
Intra	MAGEA12	P43365	NPPA	Homo sapiens	P01160	Y2H Prey Pooling	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

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