2. Gene
  3. GATAD2A - GATA zinc finger domain containing 2A Gene

GATAD2A - GATA zinc finger domain containing 2A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 GATA 锌指结构域 2A

种属: Homo sapiens

同用名: p66alpha

基因 ID: 54815 | 基因类型: protein coding

关于 GATAD2A

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,385,843-19,508,932 (from NCBI)

This gene has 13 transcripts (splice variants), 282 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 18.1), spleen (RPKM 10.8) and 25 other tissues.

功能概要

启用蛋白质-大分子适配器活动。参与转录的负调控，以 DNA 为模板。位于核质中。 NuRD 复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein-macromolecule adaptor activity. Involved in negative regulation of transcription, DNA-templated. Located in nucleoplasm. Part of NuRD complex. [provided by Alliance of Genome Resources, Apr 2022]

GATAD2A 基因产物(33)

mRNA Protein Name
NM_001300946.3 NP_001287875.1 transcriptional repressor p66-alpha isoform 1
NM_001359631.2 NP_001346560.1 transcriptional repressor p66-alpha isoform 3
NM_001384511.1 NP_001371440.1 transcriptional repressor p66-alpha isoform 1
NM_001384512.1 NP_001371441.1 transcriptional repressor p66-alpha isoform 1
NM_001384513.1 NP_001371442.1 transcriptional repressor p66-alpha isoform 1
NM_001384514.1 NP_001371443.1 transcriptional repressor p66-alpha isoform 1
NM_001384515.1 NP_001371444.1 transcriptional repressor p66-alpha isoform 1
NM_001384516.1 NP_001371445.1 transcriptional repressor p66-alpha isoform 1
NM_001384517.1 NP_001371446.1 transcriptional repressor p66-alpha isoform 1
NM_001384518.1 NP_001371447.1 transcriptional repressor p66-alpha isoform 1
NM_001384519.1 NP_001371448.1 transcriptional repressor p66-alpha isoform 1
NM_001384521.1 NP_001371450.1 transcriptional repressor p66-alpha isoform 1
NM_001384522.1 NP_001371451.1 transcriptional repressor p66-alpha isoform 1
NM_001384523.1 NP_001371452.1 transcriptional repressor p66-alpha isoform 1
NM_001384524.1 NP_001371453.1 transcriptional repressor p66-alpha isoform 1
NM_001384525.1 NP_001371454.1 transcriptional repressor p66-alpha isoform 1
NM_001384526.1 NP_001371455.1 transcriptional repressor p66-alpha isoform 1
NM_001384527.1 NP_001371456.1 transcriptional repressor p66-alpha isoform 1
NM_001384528.1 NP_001371457.1 transcriptional repressor p66-alpha isoform 1
NM_001384529.1 NP_001371458.1 transcriptional repressor p66-alpha isoform 2
NM_001384530.1 NP_001371459.1 transcriptional repressor p66-alpha isoform 2
NM_001384531.1 NP_001371460.1 transcriptional repressor p66-alpha isoform 2
NM_001384532.1 NP_001371461.1 transcriptional repressor p66-alpha isoform 2
NM_001384533.1 NP_001371462.1 transcriptional repressor p66-alpha isoform 2
NM_001384534.1 NP_001371463.1 transcriptional repressor p66-alpha isoform 3
NM_001384535.1 NP_001371464.1 transcriptional repressor p66-alpha isoform 3
NM_001384536.1 NP_001371465.1 transcriptional repressor p66-alpha isoform 3
NM_001384537.1 NP_001371466.1 transcriptional repressor p66-alpha isoform 4
NM_001384538.1 NP_001371467.1 transcriptional repressor p66-alpha isoform 5
NM_001384539.1 NP_001371468.1 transcriptional repressor p66-alpha isoform 6
NM_001384540.1 NP_001371469.1 transcriptional repressor p66-alpha isoform 7
NM_001384541.1 NP_001371470.1 transcriptional repressor p66-alpha isoform 7
NM_017660.5 NP_060130.3 transcriptional repressor p66-alpha isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12183469 GOA
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
12183469 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromatin remodeling IDA
IDA: 通过直接分析推断
9790534 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12183469 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NuRD complex IDA
IDA: 通过直接分析推断
12183469 GOA
located in nucleus IDA
IDA: 通过直接分析推断
12183469 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcriptional repressor p66-alpha

GATA zinc finger domain-containing protein 2A

GATAD2A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GATAD2A Q86YP4 KRT32 Homo sapiens Q14532
Y2H Prey Pooling
32296183
Intra GATAD2A Q86YP4 KRT32 Homo sapiens Q14532
Y2H Array
32296183
Intra GATAD2A Q86YP4 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra GATAD2A Q86YP4 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra GATAD2A Q86YP4 MBD3L1 Homo sapiens Q8WWY6
Y2H Prey Pooling
32296183
Intra GATAD2A Q86YP4 MBD3L1 Homo sapiens Q8WWY6
Validated Y2H
32296183
Intra GATAD2A Q86YP4 MBD3L1 Homo sapiens Q8WWY6
Y2H Array
32296183
Intra GATAD2A Q86YP4 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra GATAD2A Q86YP4 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra GATAD2A Q86YP4 MBD2 Homo sapiens Q9UBB5
Anti Tag CoIP
33961781
Intra GATAD2A Q86YP4 MBD2 Homo sapiens Q9UBB5
Validated Y2H
32296183
Intra GATAD2A Q86YP4 MBD2 Homo sapiens Q9UBB5
Lumier
32814053
Intra GATAD2A Q86YP4 MBD2 Homo sapiens Q9UBB5
Y2H Array
32296183
Intra GATAD2A Q86YP4 MBD2 Homo sapiens Q9UBB5
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10326 Z-ATAD-FMK Inhibitor / 否
HY-RS05296 GATAD2A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GATAD2A RGD RGD:1310596
Felis catus GATAD2A VGNC VGNC:62477
Mus musculus GATAD2A MGD MGI:2384585
Bos taurus GATAD2A VGNC VGNC:29271
Canis familiaris GATAD2A VGNC VGNC:41126
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