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  2. RANBP3L - RAN binding protein 3 like Gene

RANBP3L - RAN binding protein 3 like Gene

中文名称:RAN 结合蛋白 3 样

种属: Homo sapiens

基因 ID: 202151 | 基因类型: protein coding

关于 RANBP3L

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:36,246,913-36,301,902 (from NCBI)

This gene has 4 transcripts (splice variants), 141 orthologues and 10 paralogues. Biased expression in brain (RPKM 8.6), kidney (RPKM 8.4) and 11 other tissues.

功能概要

启用 SMAD 绑定活动。预计参与多个过程,包括参与骨骼发育的间充质细胞分化;成骨细胞分化的负调节;和成肌细胞分化的正调节。预测为核孔的一部分。预计在细胞质中有活性。 [由基因组资源联盟提供,2022 年 4 月]

Enables SMAD binding activity. Predicted to be involved in several processes, including mesenchymal cell differentiation involved in bone development; negative regulation of osteoblast differentiation; and positive regulation of myoblast differentiation. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RANBP3L 基因产物(10)

mRNA Protein Name
NM_001161429.3 NP_001154901.1 ran-binding protein 3-like isoform 1
NM_001323273.2 NP_001310202.1 ran-binding protein 3-like isoform 3
NM_001323274.2 NP_001310203.1 ran-binding protein 3-like isoform 4
NM_001323275.2 NP_001310204.1 ran-binding protein 3-like isoform 5
NM_001323276.2 NP_001310205.1 ran-binding protein 3-like isoform 6
NM_001323277.2 NP_001310206.1 ran-binding protein 3-like isoform 7
NM_001323278.2 NP_001310207.1 ran-binding protein 3-like isoform 8
NM_001323279.2 NP_001310208.1 ran-binding protein 3-like isoform 9
NM_001323280.2 NP_001310209.1 ran-binding protein 3-like isoform 10
NM_145000.5 NP_659437.3 ran-binding protein 3-like isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SMAD binding IPI
IPI: 通过物理相互作用推断
25755279 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RANBP3L 蛋白结构

Ran_BP1

Ran_BP1: RanBP1 domain (288 - 378)

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  • 400
  • 465 a.a.
蛋白主名 其他名称

ran-binding protein 3-like

RANBP3L 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra RANBP3L Q86VV4 KIF24 Homo sapiens Q5T7B8-2
Y2H Prey Pooling
32296183
Intra RANBP3L Q86VV4 KIF24 Homo sapiens Q5T7B8-2
Y2H Array
32296183
Intra RANBP3L Q86VV4 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra RANBP3L Q86VV4 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra RANBP3L Q86VV4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra RANBP3L Q86VV4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra RANBP3L Q86VV4 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra RANBP3L Q86VV4 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra RANBP3L Q86VV4 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra RANBP3L Q86VV4 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Mus musculus RANBP3L MGD MGI:2444654
Felis catus RANBP3L VGNC VGNC:64489
Macaca mulatta RANBP3L VGNC VGNC:110438
Rattus norvegicus RANBP3L RGD RGD:1307559
Bos taurus RANBP3L VGNC VGNC:33711