SHC3 - SHC adaptor protein 3 Gene

中文名称：SHC 衔接蛋白 3

种属: Homo sapiens

同用名: RAI; NSHC; SHCC; N-Shc

基因 ID: 53358 | 基因类型: protein coding

关于 SHC3

Cytogenetic location: 9q22.1 Genomic coordinates (GRCh38): 9:89,005,771-89,178,818 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 3 paralogues. Biased expression in brain (RPKM 9.5), adrenal (RPKM 2.7) and 2 other tissues.

功能概要

启用磷酸酪氨酸残基结合活性。预测参与跨膜受体蛋白酪氨酸激酶信号通路。预测作用于谷氨酸能突触传递和学习或记忆的上游或内部。预测位于胞质溶胶中。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Enables phosphotyrosine residue binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within glutamatergic synaptic transmission and learning or memory. Predicted to be located in cytosol. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SHC3 基因产物(1)

mRNA	Protein	Name
NM_016848.6	NP_058544.3	SHC-transforming protein 3

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables phosphotyrosine residue binding	IPI IPI: 通过物理相互作用推断	20624904	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	11877420	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SHC3 蛋白结构

PID

SH2

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100
200
300
400
500
594 a.a.

蛋白主名

其他名称

SHC-transforming protein 3

SH2 domain protein C3

SHC3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	SHC3	Q92529	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT40	Homo sapiens	Q6A162	Y2H Array	32296183
Intra	SHC3	Q92529	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	SHC3	Q92529	PPP1R16B	Homo sapiens	Q96T49	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PPP1R16B	Homo sapiens	Q96T49	Validated Y2H	32296183
Intra	SHC3	Q92529	PPP1R16B	Homo sapiens	Q96T49	Y2H Array	32296183
Intra	SHC3	Q92529	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	SHC3	Q92529	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	SHC3	Q92529	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT35	Homo sapiens	Q92764	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT35	Homo sapiens	Q92764	Y2H Array	32296183
Intra	SHC3	Q92529	KRT35	Homo sapiens	Q92764	Validated Y2H	32296183
Intra	SHC3	Q92529	DOK3	Homo sapiens	Q7L591-3	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	DOK3	Homo sapiens	Q7L591-3	Y2H Array	32296183
Intra	SHC3	Q92529	REL	Homo sapiens	Q04864-2	Y2H Array	32296183
Intra	SHC3	Q92529	REL	Homo sapiens	Q04864-2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	YPEL5	Homo sapiens	P62699	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	YPEL5	Homo sapiens	P62699	Y2H Array	32296183
Intra	SHC3	Q92529	KRT39	Homo sapiens	Q6A163	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT39	Homo sapiens	Q6A163	Y2H Array	32296183
Intra	SHC3	Q92529	USP54	Homo sapiens	Q70EL1-9	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	USP54	Homo sapiens	Q70EL1-9	Y2H Array	32296183
Intra	SHC3	Q92529	ZMYND12	Homo sapiens	Q9H0C1	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	ZMYND12	Homo sapiens	Q9H0C1	Y2H Array	32296183
Intra	SHC3	Q92529	ZMYND12	Homo sapiens	Q9H0C1	Validated Y2H	32296183
Intra	SHC3	Q92529	WWOX	Homo sapiens	Q9NZC7-5	Y2H Array	32296183
Intra	SHC3	Q92529	WWOX	Homo sapiens	Q9NZC7-5	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32296183
Intra	SHC3	Q92529	ANKRD10	Homo sapiens	Q9NXR5-2	Validated Y2H	32296183
Intra	SHC3	Q92529	ANKRD10	Homo sapiens	Q9NXR5-2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	ANKRD10	Homo sapiens	Q9NXR5-2	Y2H Array	32296183
Intra	SHC3	Q92529	VPS28	Homo sapiens	Q9UK41-2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	VPS28	Homo sapiens	Q9UK41-2	Validated Y2H	32296183
Intra	SHC3	Q92529	VPS28	Homo sapiens	Q9UK41-2	Y2H Array	32296183
Intra	SHC3	Q92529	TSC1	Homo sapiens	Q86WV8	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	TSC1	Homo sapiens	Q86WV8	Y2H Array	32296183
Intra	SHC3	Q92529	KIT	Homo sapiens	P10721	FPS	24728074
Intra	SHC3	Q92529	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	TRIM35	Homo sapiens	Q9UPQ4-2	Validated Y2H	32296183
Intra	SHC3	Q92529	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Array	32296183
Intra	SHC3	Q92529	CDCA4	Homo sapiens	Q9BXL8	Validated Y2H	32296183
Intra	SHC3	Q92529	CDCA4	Homo sapiens	Q9BXL8	Y2H Array	32296183
Intra	SHC3	Q92529	CDCA4	Homo sapiens	Q9BXL8	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	FTO	Homo sapiens	Q9C0B1-2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	FTO	Homo sapiens	Q9C0B1-2	Validated Y2H	32296183
Intra	SHC3	Q92529	FTO	Homo sapiens	Q9C0B1-2	Y2H Array	32296183
Intra	SHC3	Q92529	ASPG	Homo sapiens	Q86U10	Y2H Array	32296183
Intra	SHC3	Q92529	ASPG	Homo sapiens	Q86U10	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
Intra	SHC3	Q92529	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	UBAP2	Homo sapiens	Q5T6F2	Y2H Array	32296183
Intra	SHC3	Q92529	UBAP2	Homo sapiens	Q5T6F2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PRKAR1B	Homo sapiens	P31321	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PRKAR1B	Homo sapiens	P31321	Y2H Array	32296183
Intra	SHC3	Q92529	PNMA1	Homo sapiens	Q8ND90	Y2H Array	32296183
Intra	SHC3	Q92529	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	SMYD3	Homo sapiens	Q9H7B4	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	SMYD3	Homo sapiens	Q9H7B4	Y2H Array	32296183
Intra	SHC3	Q92529	SMYD3	Homo sapiens	Q9H7B4	Validated Y2H	32296183
Intra	SHC3	Q92529	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	SHC3	Q92529	TRAF1	Homo sapiens	Q13077	Y2H Array	32296183
Intra	SHC3	Q92529	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PSMD8	Homo sapiens	P48556	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PSMD8	Homo sapiens	P48556	Y2H Array	32296183
Intra	SHC3	Q92529	BMF	Homo sapiens	Q96LC9	Validated Y2H	32296183
Intra	SHC3	Q92529	BMF	Homo sapiens	Q96LC9	Y2H Array	32296183
Intra	SHC3	Q92529	BMF	Homo sapiens	Q96LC9	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	CCNC	Homo sapiens	P24863	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	CCNC	Homo sapiens	P24863	Y2H Array	32296183
Intra	SHC3	Q92529	CEACAM6	Homo sapiens	P40199	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	CEACAM6	Homo sapiens	P40199	Y2H Array	32296183
Intra	SHC3	Q92529	COPS6	Homo sapiens	Q7L5N1	Y2H Array	32296183
Intra	SHC3	Q92529	COPS6	Homo sapiens	Q7L5N1	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	SHC3	Q92529	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	SHC3	Q92529	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	SHC3	Q92529	ERBB2	Homo sapiens	P04626	Protein Array	16273093
Intra	SHC3	Q92529	CT55	Homo sapiens	Q8WUE5	Y2H Array	32296183
Intra	SHC3	Q92529	CT55	Homo sapiens	Q8WUE5	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	PMF1	Homo sapiens	Q6P1K2	Y2H Array	32296183
Intra	SHC3	Q92529	PMF1	Homo sapiens	Q6P1K2	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	STX11	Homo sapiens	O75558	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	STX11	Homo sapiens	O75558	Y2H Array	32296183
Intra	SHC3	Q92529	ERBB3	Homo sapiens	P21860	Protein Array	16273093
Intra	SHC3	Q92529	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	32296183
Intra	SHC3	Q92529	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	APP	Homo sapiens	P05067	Pull Down	11877420
Intra	SHC3	Q92529	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956
Intra	SHC3	Q92529	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	SHC3	Q92529	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	SHC3	Q92529	KRT86	Homo sapiens	O43790	Y2H Array	32296183
Intra	SHC3	Q92529	KRT86	Homo sapiens	O43790	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Spinal Cord Ependymoma

Ependymal Neoplasm Of The Spinal Cord	Spinal Ependymoma
Ependymoma Of Spinal Cord

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12858	SHC3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	SHC3	VGNC	VGNC:46141
Mus musculus	SHC3	MGD	MGI:106179
Felis catus	SHC3	VGNC	VGNC:97626
Bos taurus	SHC3	VGNC	VGNC:34591
Rattus norvegicus	SHC3	RGD	RGD:69348

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SHC3 - SHC adaptor protein 3 Gene

关于 SHC3

功能概要

SHC3 基因产物(1)

SHC3 蛋白结构

SHC3 蛋白互作信息

关联疾病

直系同源

热门区域

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SHC3 - SHC adaptor protein 3 Gene

关于 SHC3

功能概要

SHC3 基因产物(1)

SHC3 蛋白结构

SHC3 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

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