2. Gene
  3. PID1 - phosphotyrosine interaction domain containing 1 Gene

PID1 - phosphotyrosine interaction domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含磷酸酪氨酸相互作用域 1

种属: Homo sapiens

同用名: PCLI1; NYGGF4; P-CLI1; HMFN2073

基因 ID: 55022 | 基因类型: protein coding

关于 PID1

Cytogenetic location: 2q36.3 Genomic coordinates (GRCh38): 2:229,023,973-229,271,287 (from NCBI)

This gene has 6 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in brain (RPKM 7.9), liver (RPKM 5.4) and 24 other tissues.

功能概要

参与多个过程，包括线粒体形态发生；磷酸盐代谢过程的负调节；和大分子代谢过程的正向调控。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in several processes, including mitochondrion morphogenesis; negative regulation of phosphate metabolic process; and positive regulation of macromolecule metabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PID1 基因产物(5)

mRNA Protein Name
NM_001100818.2 NP_001094288.1 PTB-containing, cubilin and LRP1-interacting protein isoform 2
NM_001330156.1 NP_001317085.1 PTB-containing, cubilin and LRP1-interacting protein isoform 3
NM_001330157.2 NP_001317086.1 PTB-containing, cubilin and LRP1-interacting protein isoform 4
NM_001330158.2 NP_001317087.1 PTB-containing, cubilin and LRP1-interacting protein isoform 5
NM_017933.5 NP_060403.3 PTB-containing, cubilin and LRP1-interacting protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
NOT involved in fat cell differentiation IDA
IDA: 通过直接分析推断
16815647 GOA
involved in mitochondrion organization IMP
IMP: 通过突变表型推断
20165904 GOA
involved in negative regulation of ATP biosynthetic process IMP
IMP: 通过突变表型推断
20165904 GOA
involved in negative regulation of D-glucose import IDA
IDA: 通过直接分析推断
19079291 GOA
involved in negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
19079291 GOA
involved in negative regulation of protein localization to plasma membrane IDA
IDA: 通过直接分析推断
19079291 GOA
involved in negative regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
19079291 GOA
involved in positive regulation of fat cell proliferation IDA
IDA: 通过直接分析推断
16815647 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
20165904 GOA
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
20165904 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20165904 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16815647 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PID1 蛋白结构

PID_2

PID_2: Phosphotyrosine interaction domain (PTB/PID) (92 - 233)

  • 0
  • 100
  • 200
  • 250 a.a.
蛋白主名 其他名称

PTB-containing, cubilin and LRP1-interacting protein

phosphotyrosine interaction domain-containing protein 1

PID1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PID1 Q7Z2X4 ADAMTSL4 Homo sapiens Q6UY14-3
Validated Y2H
25416956
Intra PID1 Q7Z2X4 GOPC Homo sapiens Q9HD26
Validated Y2H
25416956
Intra PID1 Q7Z2X4 GOPC Homo sapiens Q9HD26
Y2H Array
25416956
Intra PID1 Q7Z2X4 q96t11_human Homo sapiens Q96T11
Anti Tag CoIP
33961781
Intra PID1 Q7Z2X4 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 MDFI Homo sapiens Q99750
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 NME1 Homo sapiens P15531
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 NME1 Homo sapiens P15531
Y2H Array
25416956
Intra PID1 Q7Z2X4 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 THAP1 Homo sapiens Q9NVV9
Y2H Array
25416956
Intra PID1 Q7Z2X4 CBY2 Homo sapiens Q8NA61
Validated Y2H
25416956
Intra PID1 Q7Z2X4 CBY2 Homo sapiens Q8NA61
Y2H Array
25416956
Intra PID1 Q7Z2X4 BANP Homo sapiens Q8N9N5
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 CRX Homo sapiens O43186
Y2H Prey Pooling
25416956
Intra PID1 Q7Z2X4 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
Intra PID1 Q7Z2X4 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10480 PID1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PID1 VGNC VGNC:32862
Canis familiaris PID1 VGNC VGNC:44526
Rattus norvegicus PID1 RGD RGD:1560766
Felis catus PID1 VGNC VGNC:80302
Macaca mulatta PID1 VGNC VGNC:75869
Mus musculus PID1 MGD MGI:2138391
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