RAMAC - RNA guanine-7 methyltransferase activating subunit Gene

中文名称：RNA 鸟嘌呤 7 甲基转移酶激活亚基

种属: Homo sapiens

同用名: RAM; RAMMET; C15orf18; FAM103A1; HsT19360

基因 ID: 83640 | 基因类型: protein coding

关于 RAMAC

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:82,986,210-82,991,057 (from NCBI)

This gene has 1 transcript (splice variant), 187 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 19.2), colon (RPKM 16.4) and 25 other tissues.

功能概要

启用 RNA 结合活性和酶激活剂活性。参与甲基化和 mRNA 加帽酶向 RNA 聚合酶 II 全酶复合物的募集。位于核质中。部分 mRNA 帽结合活性复合物和 mRNA 帽甲基转移酶复合物。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity and Enzyme activator activity. Involved in methylation and recruitment of mRNA capping Enzyme to RNA polymerase II holoenzyme complex. Located in nucleoplasm. Part of mRNA cap binding activity complex and mRNA cap methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

RAMAC 基因产物(1)

mRNA	Protein	Name
NM_031452.4	NP_113640.1	RNA guanine-N7 methyltransferase activating subunit

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA binding	IDA IDA: 通过直接分析推断	22099306	GOA
enables enzyme activator activity	IDA IDA: 通过直接分析推断	27422871	GOA
enables molecular function activator activity	EXP EXP: 通过实验结果推断	27422871	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	22099306	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in 7-methylguanosine mRNA capping	IDA IDA: 通过直接分析推断	22099306	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of mRNA cap methyltransferase RNMT:RAMAC complex	IDA IDA: 通过直接分析推断	22099306	GOA
part of mRNA capping enzyme complex	IDA IDA: 通过直接分析推断	27422871	GOA
located in nucleus	IDA IDA: 通过直接分析推断	22099306	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RAMAC 蛋白结构

RAM

0
100
118 a.a.

蛋白主名

其他名称

RNA guanine-N7 methyltransferase activating subunit

RNMT activating mRNA cap methyltransferase subunit

RAMAC 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	RAMAC	Q9BTL3	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	USP54	Homo sapiens	Q70EL1-9	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	USP54	Homo sapiens	Q70EL1-9	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	FOXI1	Homo sapiens	Q12951-2	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	FOXI1	Homo sapiens	Q12951-2	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	WWOX	Homo sapiens	Q9NZC7-5	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	WWOX	Homo sapiens	Q9NZC7-5	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	FAM168B	Homo sapiens	A1KXE4-2	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	FAM168B	Homo sapiens	A1KXE4-2	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	C10orf55	Homo sapiens	Q5SWW7	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	C10orf55	Homo sapiens	Q5SWW7	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	OXER1	Homo sapiens	Q8TDS5	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	OXER1	Homo sapiens	Q8TDS5	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	NAF1	Homo sapiens	Q96HR8	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	NAF1	Homo sapiens	Q96HR8	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	VPS37C	Homo sapiens	A5D8V6	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	VPS37C	Homo sapiens	A5D8V6	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	PRR3	Homo sapiens	P79522	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	PRR3	Homo sapiens	P79522	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	BAG4	Homo sapiens	O95429	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	BAG4	Homo sapiens	O95429	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	PSMA3	Homo sapiens	P25788	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	PSMA3	Homo sapiens	P25788	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	SF3B4	Homo sapiens	Q15427	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	SF3B4	Homo sapiens	Q15427	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	HNRNPH1	Homo sapiens	P31943	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	HNRNPH1	Homo sapiens	P31943	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	AKAP8L	Homo sapiens	Q9ULX6	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	AKAP8L	Homo sapiens	Q9ULX6	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	AKAP8L	Homo sapiens	Q9ULX6	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	TRIM42	Homo sapiens	Q8IWZ5	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	INCA1	Homo sapiens	Q0VD86	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	HNRNPK	Homo sapiens	P61978-2	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	HNRNPK	Homo sapiens	P61978-2	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	MAGED1	Homo sapiens	Q9Y5V3	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	MAGED1	Homo sapiens	Q9Y5V3	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	MAGED1	Homo sapiens	Q9Y5V3	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	25416956
Intra	RAMAC	Q9BTL3	TRIM27	Homo sapiens	P14373	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	DAZAP2	Homo sapiens	Q15038	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	DAZAP2	Homo sapiens	Q15038	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	RINT1	Homo sapiens	Q6NUQ1	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	RINT1	Homo sapiens	Q6NUQ1	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	KRT15	Homo sapiens	P19012	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	RAMAC	Q9BTL3	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	TRIM23	Homo sapiens	P36406	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	LZTS2	Homo sapiens	Q9BRK4	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	MAPK1IP1L	Homo sapiens	Q8NDC0	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	MAPK1IP1L	Homo sapiens	Q8NDC0	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	TEKT4	Homo sapiens	Q8WW24	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	TEKT4	Homo sapiens	Q8WW24	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	PLSCR4	Homo sapiens	Q9NRQ2	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	DAB1	Homo sapiens	O75553	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	DAB1	Homo sapiens	O75553	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	RBMY1F	Homo sapiens	Q15415	Y2H Prey Pooling	25416956
Intra	RAMAC	Q9BTL3	RBMY1F	Homo sapiens	Q15415	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	RBMY1F	Homo sapiens	Q15415	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	TEKT3	Homo sapiens	Q9BXF9	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	TEKT3	Homo sapiens	Q9BXF9	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	TEKT3	Homo sapiens	Q9BXF9	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	RNMT	Homo sapiens	O43148	Anti Tag CoIP	33961781
Intra	RAMAC	Q9BTL3	RNMT	Homo sapiens	O43148	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	RNMT	Homo sapiens	O43148	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	POU2AF1	Homo sapiens	Q16633	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	POU2AF1	Homo sapiens	Q16633	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	KRT31	Homo sapiens	Q15323	Validated Y2H	25416956
Intra	RAMAC	Q9BTL3	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	KRT31	Homo sapiens	Q15323	Y2H Array	25416956
Intra	RAMAC	Q9BTL3	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956
Intra	RAMAC	Q9BTL3	TNS2	Homo sapiens	Q63HR2	Y2H Prey Pooling	32296183
Intra	RAMAC	Q9BTL3	TNS2	Homo sapiens	Q63HR2	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	BPIFA1	Homo sapiens	Q9NP55	Y2H Array	32296183
Intra	RAMAC	Q9BTL3	BPIFA1	Homo sapiens	Q9NP55	Validated Y2H	32296183
Intra	RAMAC	Q9BTL3	BPIFA1	Homo sapiens	Q9NP55	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Murray Valley Encephalitis

Australian Encephalitis	Australian X Disease
Encephalitis Australia	Murray River Encephalitis
Australian Arboencephalitis	Australian X Disorder
Mve - [Murray Valley Encephalitis]

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11637	RAMAC Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	RAMAC	MGD	MGI:1914398
Rattus norvegicus	RAMAC	RGD	RGD:1310022
Bos taurus	RAMAC	VGNC	VGNC:55894
Canis familiaris	RAMAC	VGNC	VGNC:53171

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RAMAC - RNA guanine-7 methyltransferase activating subunit Gene

关于 RAMAC

功能概要

RAMAC 基因产物(1)

RAMAC 蛋白结构

RAMAC 蛋白互作信息

关联疾病

直系同源

热门区域

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RAMAC - RNA guanine-7 methyltransferase activating subunit Gene

关于 RAMAC

功能概要

RAMAC 基因产物(1)

RAMAC 蛋白结构

RAMAC 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

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X

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