2. Gene
  3. OXER1 - oxoeicosanoid receptor 1 Gene

OXER1 - oxoeicosanoid receptor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：含氧花生酸受体 1

种属: Homo sapiens

同用名: GPCR; GPR170; TG1019

基因 ID: 165140 | 基因类型: protein coding

关于 OXER1

Cytogenetic location: 2p21 Genomic coordinates (GRCh38): 2:42,762,499-42,764,135 (from NCBI)

This gene has 1 transcript (splice variant), 189 orthologues and 15 paralogues.

功能概要

启用 G 蛋白偶联受体活性和花生酸结合活性。参与腺苷酸环化酶抑制 G 蛋白偶联受体信号通路。预测位于质膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OXER1 基因产物(1)

mRNA Protein Name
NM_148962.5 NP_683765.2 oxoeicosanoid receptor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: 通过直接分析推断
12065583 GOA
enables 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: 通过直接分析推断
12065583 GOA
enables 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: 通过直接分析推断
12065583 GOA
enables G protein-coupled receptor activity IMP
IMP: 通过突变表型推断
12065583 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12065583 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

OXER1 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (109 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 423 a.a.
蛋白主名 其他名称

oxoeicosanoid receptor 1

5-oxo-ETE G-protein coupled receptor

OXER1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra OXER1 Q8TDS5 KRTAP4-2 Homo sapiens Q9BYR5
Validated Y2H
32296183
Intra OXER1 Q8TDS5 ASB13 Homo sapiens Q8WXK3-2
Validated Y2H
32296183
Intra OXER1 Q8TDS5 ANAPC11 Homo sapiens Q9NYG5-2
Validated Y2H
32296183
Intra OXER1 Q8TDS5 RNF38 Homo sapiens Q9H0F5
Validated Y2H
32296183
Intra OXER1 Q8TDS5 TFG Homo sapiens Q92734
Validated Y2H
32296183
Intra OXER1 Q8TDS5 NOC4L Homo sapiens Q9BVI4
Validated Y2H
32296183
Intra OXER1 Q8TDS5 ZC3H10 Homo sapiens Q96K80
Validated Y2H
32296183
Intra OXER1 Q8TDS5 RAMAC Homo sapiens Q9BTL3
Validated Y2H
32296183
Intra OXER1 Q8TDS5 RNF208 Homo sapiens Q9H0X6
Validated Y2H
32296183
Intra OXER1 Q8TDS5 PLSCR4 Homo sapiens Q9NRQ2
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Nephrogenic Diabetes Insipidus

Vasopressin-Resistant Diabetes Insipidus

Diabetes Insipidus, Nephrogenic

Diabetes Insipidus Nephrogenic

Congenital Nephrogenic Diabetes Insipidus

Adh Resistant Diabetes Insipidus

Diabetes Insipidus Nephrogenic X-Linked

Diabetes Insipidus Nephrogenic Type 1

Adh-Resistant Diabetes Insipidus

Diabetes Insipidus Renalis

Ndi

Renal Diabetes Insipidus

Familial Nephrogenic Diabetes

Antidiuretic-Hormone-Resistant Diabetes Insipidus

Adiuretin-Resistant Diabetes Insipidus

Ndi - [Nephrogenic Diabetes Insipidus]

Diabetes Tenuifluus

Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus

Hereditary Nephrogenic Diabetes Insipidus

Familial Nephrogenic Diabetes Insipidus

Primary Nephrogenic Diabetes Insipidus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09887 OXER1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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