2. Gene
  3. ZZZ3 - zinc finger ZZ-type containing 3 Gene

ZZZ3 - zinc finger ZZ-type containing 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锌指 ZZ 型 3

种属: Homo sapiens

同用名: ATAC1

基因 ID: 26009 | 基因类型: protein coding

关于 ZZZ3

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:77,562,416-77,683,398 (from NCBI)

This gene has 11 transcripts (splice variants) and 216 orthologues. Ubiquitous expression in thyroid (RPKM 9.6), ovary (RPKM 6.7) and 25 other tissues.

功能概要

预测启用 DNA 结合活性和锌离子结合活性。预测参与组蛋白 H4 乙酰化。位于核仁和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in histone H4 acetylation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZZZ3 基因产物(11)

mRNA Protein Name
NM_001308237.2 NP_001295166.1 ZZ-type zinc finger-containing protein 3 isoform 2
NM_001376146.1 NP_001363075.1 ZZ-type zinc finger-containing protein 3 isoform 1
NM_001376147.1 NP_001363076.1 ZZ-type zinc finger-containing protein 3 isoform 1
NM_001376148.1 NP_001363077.1 ZZ-type zinc finger-containing protein 3 isoform 3
NM_001376149.1 NP_001363078.1 ZZ-type zinc finger-containing protein 3 isoform 3
NM_001376151.1 NP_001363080.1 ZZ-type zinc finger-containing protein 3 isoform 3
NM_001376153.1 NP_001363082.1 ZZ-type zinc finger-containing protein 3 isoform 3
NM_001376154.1 NP_001363083.1 ZZ-type zinc finger-containing protein 3 isoform 3
NM_001376155.1 NP_001363084.1 ZZ-type zinc finger-containing protein 3 isoform 2
NM_001376156.1 NP_001363085.1 ZZ-type zinc finger-containing protein 3 isoform 4
NM_015534.6 NP_056349.1 ZZ-type zinc finger-containing protein 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone reader activity IDA
IDA: 通过直接分析推断
30217978 GOA
enables lysine-acetylated histone binding IDA
IDA: 通过直接分析推断
30217978 GOA
enables methylated histone binding IDA
IDA: 通过直接分析推断
30217978 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
20562830 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromatin organization IMP
IMP: 通过突变表型推断
30217978 GOA
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
19936620 GOA
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
19103755 GOA
involved in regulation of cell division IDA
IDA: 通过直接分析推断
20562830 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22055187 GOA
involved in regulation of tubulin deacetylation IMP
IMP: 通过突变表型推断
20562830 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ATAC complex IDA
IDA: 通过直接分析推断
19936620 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZZZ3 蛋白结构

Myb_DNA-binding

Myb_DNA-binding: Myb-like DNA-binding domain (654 - 702)

ZZ

ZZ: Zinc finger, ZZ type (818 - 855)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 903 a.a.
蛋白主名 其他名称

ZZ-type zinc finger-containing protein 3

ATAC component 1 homolog

ZZZ3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZZZ3 Q8IYH5 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra ZZZ3 Q8IYH5 PPP1R13B Homo sapiens Q96KQ4
Validated Y2H
32296183
Intra ZZZ3 Q8IYH5 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 CARD9 Homo sapiens Q9H257-2
Validated Y2H
32296183
Intra ZZZ3 Q8IYH5 CARD9 Homo sapiens Q9H257-2
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 CARD9 Homo sapiens Q9H257-2
Y2H Prey Pooling
32296183
Intra ZZZ3 Q8IYH5 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra ZZZ3 Q8IYH5 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Cross ZZZ3 Q8IYH5 Hoxa1 Mus musculus P09022
Pull Down
23088713
Intra ZZZ3 Q8IYH5 KAT2A Homo sapiens Q92830
Anti Bait CoIP
20562830
Intra ZZZ3 Q8IYH5 WDR5 Homo sapiens P61964
Anti Bait CoIP
24981860
Intra ZZZ3 Q8IYH5 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra ZZZ3 Q8IYH5 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 FAM124A Homo sapiens Q86V42
Y2H Array
25416956
Intra ZZZ3 Q8IYH5 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra ZZZ3 Q8IYH5 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra ZZZ3 Q8IYH5 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency 24

COXPD24

Combined Oxidative Phosphorylation Defect Type 24

Oxidative Phosphorylation Deficiency, Combined, Type 24
Combined Oxidative Phosphorylation Deficiency 20

COXPD20

Combined Oxidative Phosphorylation Defect Type 20

Oxidative Phosphorylation Deficiency, Combined, Type 20
Buruli Ulcer

Buruli Ulcer, Susceptibility To

Buruli Ulcer Disease

Mycobacterium Ulcerans

Mycobacterium Ulcerans, Susceptibility To

Bairnsdale Ulcer

Daintree Ulcer

Mossman Ulcer

Searl Ulcer

Searle'S Ulcer

Bud
Histiocytoid Hemangioma

Angiolymphoid Hyperplasia With Eosinophilia

Epithelioid Haemangioma

Epithelioid Hemangioma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16217 ZZZ3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ZZZ3 VGNC VGNC:67396
Mus musculus ZZZ3 MGD MGI:1920453
Bos taurus ZZZ3 VGNC VGNC:37397
Rattus norvegicus ZZZ3 RGD RGD:1565468
Macaca mulatta ZZZ3 VGNC VGNC:106535
Canis familiaris ZZZ3 VGNC VGNC:48871
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