2. Gene
  3. PARD6B - par-6 family cell polarity regulator beta Gene

PARD6B - par-6 family cell polarity regulator beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：par-6 系列细胞极性调节因子 beta

种属: Homo sapiens

同用名: PAR6B

基因 ID: 84612 | 基因类型: protein coding

关于 PARD6B

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:50,731,580-50,753,741 (from NCBI)

This gene has 2 transcripts (splice variants), 208 orthologues and 2 paralogues. Broad expression in kidney (RPKM 9.5), lung (RPKM 3.4) and 17 other tissues.

功能概要

该基因是 PAR6 家族的成员，编码的蛋白质具有 PSD95/Discs-large/ZO1 (PDZ) 结构域、OPR 结构域和半 Cdc42/Rac 交互结合 (CRIB) 结构域。这种细胞质蛋白作为多蛋白复合物的成员参与不对称细胞分裂和细胞极化过程。[RefSeq 提供，2008 年 7 月]

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]

PARD6B 基因产物(1)

mRNA Protein Name
NM_032521.3 NP_115910.1 partitioning defective 6 homolog beta

PARD6B 蛋白结构

PB1

PB1: PB1 domain (16 - 95)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (158 - 238)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

partitioning defective 6 homolog beta

PAR-6 beta

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10039 PARD6B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PARD6B VGNC VGNC:107850
Rattus norvegicus PARD6B RGD RGD:1308205
Canis familiaris PARD6B VGNC VGNC:54725
Bos taurus PARD6B VGNC VGNC:32584
Mus musculus PARD6B MGD MGI:2135605
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