2. Gene
  3. HSF2BP - heat shock transcription factor 2 binding protein Gene

HSF2BP - heat shock transcription factor 2 binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：热休克转录因子 2 结合蛋白

种属: Homo sapiens

同用名: POF19; MEILB2

基因 ID: 11077 | 基因类型: protein coding

关于 HSF2BP

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,444,972-43,659,488 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and is associated with 1 phenotype. Biased expression in testis (RPKM 2.8), brain (RPKM 0.5) and 6 other tissues.

功能概要

HSF2 结合蛋白 (HSF2BP) 与 HSF2 结合。相互作用发生在 HSF2 的三聚化结构域和包含两个亮氨酸拉链基序的 HSF2BP 的氨基末端亲水区域之间。因此，HSF2BP 可能参与调节 HSF2 激活。[RefSeq 提供，2008 年 7 月]

HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008]

HSF2BP 基因产物(1)

mRNA Protein Name
NM_007031.2 NP_008962.1 heat shock factor 2-binding protein
蛋白主名 其他名称

heat shock factor 2-binding protein

meiotic localizer of BRCA2

关联疾病

疾病名称 别名
Premature Ovarian Failure 19

POF19

Primary Ovarian Insufficiency 19

Poi19

Ovarian Failure, Premature, Type 19
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06410 HSF2BP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus HSF2BP MGD MGI:1921627
Canis familiaris HSF2BP VGNC VGNC:41816
Macaca mulatta HSF2BP VGNC VGNC:73532
Rattus norvegicus HSF2BP RGD RGD:1565879
Bos taurus HSF2BP VGNC VGNC:29983
Felis catus HSF2BP VGNC VGNC:102757
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