2. Gene
  3. CCDC146 - coiled-coil domain containing 146 Gene

CCDC146 - coiled-coil domain containing 146 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含卷曲螺旋结构域 146

种属: Homo sapiens

同用名: MBO2

基因 ID: 57639 | 基因类型: protein coding

关于 CCDC146

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,122,615-77,295,204 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in testis (RPKM 14.9), skin (RPKM 7.4) and 22 other tissues.

功能概要

位于中心粒。 [由基因组资源联盟提供，2022 年 4 月]

Located in centriole. [provided by Alliance of Genome Resources, Apr 2022]

CCDC146 基因产物(1)

mRNA Protein Name
NM_020879.3 NP_065930.2 coiled-coil domain-containing protein 146
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in spermatid development IMP
IMP: 通过突变表型推断
38441556 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axoneme IDA
IDA: 通过直接分析推断
38441556 GOA
located in centriole IDA
IDA: 通过直接分析推断
25074808 GOA
located in centrosome IDA
IDA: 通过直接分析推断
30094225 GOA
located in ciliary basal body IDA
IDA: 通过直接分析推断
38441556 GOA
located in midbody IDA
IDA: 通过直接分析推断
38441556 GOA
located in sperm flagellum IDA
IDA: 通过直接分析推断
38441556 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

coiled-coil domain-containing protein 146

CCDC146 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Y2H Array
32296183
Intra CCDC146 Q8IYE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MAGEA6 Homo sapiens P43360
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Array
29892012
Intra CCDC146 Q8IYE0 GAS8 Homo sapiens O95995
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GAS8 Homo sapiens O95995
Y2H Array
32296183
Intra CCDC146 Q8IYE0 GRAMD4 Homo sapiens Q6IC98
Y2H Array
32296183
Intra CCDC146 Q8IYE0 GRAMD4 Homo sapiens Q6IC98
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CDR2L Homo sapiens Q86X02
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CDR2L Homo sapiens Q86X02
Y2H Array
32296183
Intra CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PROSER3 Homo sapiens Q2NL68
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 PROSER3 Homo sapiens Q2NL68
Y2H Array
32296183
Intra CCDC146 Q8IYE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 AKAP9 Homo sapiens Q6PJH3
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 AKAP9 Homo sapiens Q6PJH3
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CDR2 Homo sapiens Q01850
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CDR2 Homo sapiens Q01850
Y2H Array
32296183
Intra CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 KRT26 Homo sapiens Q7Z3Y9
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT26 Homo sapiens Q7Z3Y9
Y2H Array
32296183
Intra CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 N4BP3 Homo sapiens O15049
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 N4BP3 Homo sapiens O15049
Y2H Array
32296183
Intra CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MCC Homo sapiens P23508
Y2H Array
32296183
Intra CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Y2H Array
32296183
Intra CCDC146 Q8IYE0 NUP62 Homo sapiens P37198
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 NUP62 Homo sapiens P37198
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra CCDC146 Q8IYE0 TXLNA Homo sapiens P40222
Y2H Array
32296183
Intra CCDC146 Q8IYE0 TXLNA Homo sapiens P40222
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Anti Tag CoIP
33961781
Intra CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Array
32296183
Intra CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Array
31515488
Intra CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Y2H Array
32296183
Intra CCDC146 Q8IYE0 INSYN1 Homo sapiens Q2T9L4
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 INSYN1 Homo sapiens Q2T9L4
Y2H Array
32296183
Intra CCDC146 Q8IYE0 BLOC1S2 Homo sapiens Q6QNY1
Y2H Array
32296183
Intra CCDC146 Q8IYE0 BLOC1S2 Homo sapiens Q6QNY1
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Y2H Array
32296183
Intra CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra CCDC146 Q8IYE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra CCDC146 Q8IYE0 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra CCDC146 Q8IYE0 THOC7 Homo sapiens Q6I9Y2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 THOC7 Homo sapiens Q6I9Y2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CCNDBP1 Homo sapiens O95273
Y2H Array
32296183
Intra CCDC146 Q8IYE0 CCNDBP1 Homo sapiens O95273
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Y2H Array
32296183
Intra CCDC146 Q8IYE0 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PDE4DIP Homo sapiens Q5VU43-2
Y2H Array
32296183
Intra CCDC146 Q8IYE0 PDE4DIP Homo sapiens Q5VU43-2
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Validated Y2H
32296183
Intra CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Y2H Array
32296183
Intra CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Intra CCDC146 Q8IYE0 KRT86 Homo sapiens O43790
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lymphogranuloma Venereum

Climatic Or Tropical Bubo

Durand-Nicolas-Favre Disease

Lymphogranuloma Inguinale

Poradenitis Inguinale

Strumous Bubo

Lgv
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02033 CCDC146 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CCDC146 VGNC VGNC:60464
Rattus norvegicus CCDC146 RGD RGD:1559535
Canis familiaris CCDC146 VGNC VGNC:38798
Bos taurus CCDC146 VGNC VGNC:26854
Macaca mulatta CCDC146 VGNC VGNC:70902
Mus musculus CCDC146 MGD MGI:1922422
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