CCDC146 - coiled-coil domain containing 146 Gene

中文名称：含卷曲螺旋结构域 146

种属: Homo sapiens

同用名: MBO2

基因 ID: 57639 | 基因类型: protein coding

关于 CCDC146

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,122,615-77,295,204 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in testis (RPKM 14.9), skin (RPKM 7.4) and 22 other tissues.

功能概要

位于中心粒。 [由基因组资源联盟提供，2022 年 4 月]

Located in centriole. [provided by Alliance of Genome Resources, Apr 2022]

CCDC146 基因产物(1)

mRNA	Protein	Name
NM_020879.3	NP_065930.2	coiled-coil domain-containing protein 146

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in spermatid development	IMP IMP: 通过突变表型推断	38441556	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in axoneme	IDA IDA: 通过直接分析推断	38441556	GOA
located in centriole	IDA IDA: 通过直接分析推断	25074808	GOA
located in centrosome	IDA IDA: 通过直接分析推断	30094225	GOA
located in ciliary basal body	IDA IDA: 通过直接分析推断	38441556	GOA
located in midbody	IDA IDA: 通过直接分析推断	38441556	GOA
located in sperm flagellum	IDA IDA: 通过直接分析推断	38441556	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

coiled-coil domain-containing protein 146

CCDC146 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CCDC146	Q8IYE0	CENPH	Homo sapiens	Q9H3R5	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CENPH	Homo sapiens	Q9H3R5	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	CENPH	Homo sapiens	Q9H3R5	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	NECAB2	Homo sapiens	Q7Z6G3-2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	NECAB2	Homo sapiens	Q7Z6G3-2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MAGEA6	Homo sapiens	P43360	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT34	Homo sapiens	O76011	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT38	Homo sapiens	O76015	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT38	Homo sapiens	O76015	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT38	Homo sapiens	O76015	Y2H Array	29892012
种属内	CCDC146	Q8IYE0	GAS8	Homo sapiens	O95995	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GAS8	Homo sapiens	O95995	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	GRAMD4	Homo sapiens	Q6IC98	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	GRAMD4	Homo sapiens	Q6IC98	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	TRIML2	Homo sapiens	Q8N7C3	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	TRIML2	Homo sapiens	Q8N7C3	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	TRIML2	Homo sapiens	Q8N7C3	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CDR2L	Homo sapiens	Q86X02	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CDR2L	Homo sapiens	Q86X02	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	TEPSIN	Homo sapiens	Q96N21	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	TEPSIN	Homo sapiens	Q96N21	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	TEPSIN	Homo sapiens	Q96N21	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PROSER3	Homo sapiens	Q2NL68	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	PROSER3	Homo sapiens	Q2NL68	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CBY2	Homo sapiens	Q8NA61-2	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	CBY2	Homo sapiens	Q8NA61-2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CBY2	Homo sapiens	Q8NA61-2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	AKAP9	Homo sapiens	Q6PJH3	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	AKAP9	Homo sapiens	Q6PJH3	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CDR2	Homo sapiens	Q01850	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CDR2	Homo sapiens	Q01850	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	LHX3	Homo sapiens	Q9UBR4-2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	LHX3	Homo sapiens	Q9UBR4-2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	LHX3	Homo sapiens	Q9UBR4-2	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	KRT26	Homo sapiens	Q7Z3Y9	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT26	Homo sapiens	Q7Z3Y9	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	VPS28	Homo sapiens	Q9UK41-2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	VPS28	Homo sapiens	Q9UK41-2	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	VPS28	Homo sapiens	Q9UK41-2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	TRIM54	Homo sapiens	Q9BYV2	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	N4BP3	Homo sapiens	O15049	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	N4BP3	Homo sapiens	O15049	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	MIPOL1	Homo sapiens	Q8TD10	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MIPOL1	Homo sapiens	Q8TD10	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	MIPOL1	Homo sapiens	Q8TD10	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PPP2R3C	Homo sapiens	Q969Q6	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	PPP2R3C	Homo sapiens	Q969Q6	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PPP2R3C	Homo sapiens	Q969Q6	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	VPS52	Homo sapiens	Q8N1B4	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	VPS52	Homo sapiens	Q8N1B4	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT24	Homo sapiens	Q2M2I5	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT24	Homo sapiens	Q2M2I5	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MCC	Homo sapiens	P23508	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MCC	Homo sapiens	P23508	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	SH3BP1	Homo sapiens	Q9Y3L3	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	SH3BP1	Homo sapiens	Q9Y3L3	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	SH3BP1	Homo sapiens	Q9Y3L3	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	NUP62	Homo sapiens	P37198	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT16	Homo sapiens	P08779	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT16	Homo sapiens	P08779	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	TXLNA	Homo sapiens	P40222	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	TXLNA	Homo sapiens	P40222	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GMNN	Homo sapiens	O75496	Anti Tag CoIP	33961781
种属内	CCDC146	Q8IYE0	GMNN	Homo sapiens	O75496	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	GMNN	Homo sapiens	O75496	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GMNN	Homo sapiens	O75496	Y2H Array	31515488
种属内	CCDC146	Q8IYE0	NAP1L2	Homo sapiens	Q9ULW6	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	NAP1L2	Homo sapiens	Q9ULW6	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	NAP1L2	Homo sapiens	Q9ULW6	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	INSYN1	Homo sapiens	Q2T9L4	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	INSYN1	Homo sapiens	Q2T9L4	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	BLOC1S2	Homo sapiens	Q6QNY1	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	BLOC1S2	Homo sapiens	Q6QNY1	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GPRASP2	Homo sapiens	Q96D09	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GPRASP2	Homo sapiens	Q96D09	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	GPRASP2	Homo sapiens	Q96D09	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	FSD2	Homo sapiens	A1L4K1	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	FSD2	Homo sapiens	A1L4K1	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	THOC7	Homo sapiens	Q6I9Y2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	THOC7	Homo sapiens	Q6I9Y2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	MAGEA11	Homo sapiens	P43364	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MAGEA11	Homo sapiens	P43364	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	USHBP1	Homo sapiens	Q8N6Y0	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	PLEKHF2	Homo sapiens	Q9H8W4	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CEP44	Homo sapiens	Q9C0F1	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CEP44	Homo sapiens	Q9C0F1	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	CEP44	Homo sapiens	Q9C0F1	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CCNDBP1	Homo sapiens	O95273	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CCDC197	Homo sapiens	Q8NCU1	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	CCDC197	Homo sapiens	Q8NCU1	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	CCDC197	Homo sapiens	Q8NCU1	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PDE4DIP	Homo sapiens	Q5VU43-2	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	PDE4DIP	Homo sapiens	Q5VU43-2	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	MRFAP1	Homo sapiens	Q9Y605	Validated Y2H	32296183
种属内	CCDC146	Q8IYE0	MRFAP1	Homo sapiens	Q9Y605	Y2H Array	32296183
种属内	CCDC146	Q8IYE0	MRFAP1	Homo sapiens	Q9Y605	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT86	Homo sapiens	O43790	Y2H Prey Pooling	32296183
种属内	CCDC146	Q8IYE0	KRT86	Homo sapiens	O43790	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Lymphogranuloma Venereum

Climatic Or Tropical Bubo	Durand-Nicolas-Favre Disease
Lymphogranuloma Inguinale	Poradenitis Inguinale
Strumous Bubo	Lgv

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02033	CCDC146 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	CCDC146	VGNC	VGNC:60464
Rattus norvegicus	CCDC146	RGD	RGD:1559535
Canis familiaris	CCDC146	VGNC	VGNC:38798
Bos taurus	CCDC146	VGNC	VGNC:26854
Macaca mulatta	CCDC146	VGNC	VGNC:70902
Mus musculus	CCDC146	MGD	MGI:1922422

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