2. Gene
  3. N4BP3 - NEDD4 binding protein 3 Gene

N4BP3 - NEDD4 binding protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NEDD4 结合蛋白 3

种属: Homo sapiens

同用名: LZTS4

基因 ID: 23138 | 基因类型: protein coding

关于 N4BP3

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:178,113,532-178,127,034 (from NCBI)

This gene has 1 transcript (splice variant) and 197 orthologues. Broad expression in placenta (RPKM 5.5), esophagus (RPKM 3.2) and 20 other tissues.

功能概要

预计参与神经系统发育。预测位于轴突和树突中。预测在细胞质囊泡中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in nervous system development. Predicted to be located in axon and dendrite. Predicted to be active in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

N4BP3 基因产物(1)

mRNA Protein Name
NM_015111.2 NP_055926.1 NEDD4-binding protein 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IDA
IDA: 通过直接分析推断
34880843 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26496610 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of positive effect innate immune response IDA
IDA: 通过直接分析推断
23951545 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

N4BP3 蛋白结构

Fez1

Fez1: Fez1 (366 - 428)

Fez1

Fez1: Fez1 (441 - 526)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 544 a.a.
蛋白主名 其他名称

NEDD4-binding protein 3

N4BP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
N4BP3 O15049 CNKSR3 Homo sapiens Q6P9H4
Validated Y2H
32296183
种属内
N4BP3 O15049 CCDC146 Homo sapiens Q8IYE0
Validated Y2H
32296183
种属内
N4BP3 O15049 PRR35 Homo sapiens P0CG20
Validated Y2H
32296183
种属内
N4BP3 O15049 CCDC17 Homo sapiens Q96LX7-5
Validated Y2H
32296183
种属内
N4BP3 O15049 RNF41 Homo sapiens Q9H4P4
Validated Y2H
32296183
种属内
N4BP3 O15049 LMO4 Homo sapiens P61968
Validated Y2H
32296183
种属内
N4BP3 O15049 RUSC1 Homo sapiens Q9BVN2
Validated Y2H
32296183
种属内
N4BP3 O15049 RFC5 Homo sapiens P40937
Validated Y2H
32296183
种属内
N4BP3 O15049 UBASH3A Homo sapiens P57075-2
Validated Y2H
32296183
种属内
N4BP3 O15049 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
种属内
N4BP3 O15049 SPG21 Homo sapiens Q9NZD8
Validated Y2H
32296183
种属内
N4BP3 O15049 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Developmental And Epileptic Encephalopathy 5

Epileptic Encephalopathy, Early Infantile, 5

DEE5

Eiee5

Developmental And Epileptic Encephalopathy, 5

Early Infantile Epileptic Encephalopathy 5

Encephalopathy, Epileptic, Early Infantile, Type 5
Developmental And Epileptic Encephalopathy 4

DEE4

Epileptic Encephalopathy, Early Infantile, 4

Eiee4

Early Infantile Epileptic Encephalopathy 4

Stxbp1-Related Early-Onset Encephalopathy

Early Myoclonic Encephalopathy

Developmental And Epileptic Encephalopathy, 4

Stxbp1 Disorders

Stxbp1 Encephalopathy

Developmental And Epileptic Encephalopathy, Type 4

Early-Infantile Epileptic Encephalopathy 4

Stxbp1 Encephalopathy With Epilepsy

Stxbp1 Epileptic Encephalopathy

Stxbp1-Related Developmental And Epileptic Encephalopathy

Stxbp1-Related Epileptic Encephalopathy

Eme

Neonatal Epilepsy With Suppression-Burst Pattern

Encephalopathy, Epileptic, Early Infantile, Type 4
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08983 N4BP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus N4BP3 RGD RGD:1308356
Macaca mulatta N4BP3 VGNC VGNC:75053
Bos taurus N4BP3 VGNC VGNC:31853
Canis familiaris N4BP3 VGNC VGNC:43598
Felis catus N4BP3 VGNC VGNC:102262
Mus musculus N4BP3 MGD MGI:2442218
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