2. Gene
  3. THOC7 - THO complex subunit 7 Gene

THOC7 - THO complex subunit 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：THO 复合亚基 7

种属: Homo sapiens

同用名: fSAP24; hTREX30; NIF3L1BP1

基因 ID: 80145 | 基因类型: protein coding

关于 THOC7

Cytogenetic location: 3p14.1 Genomic coordinates (GRCh38): 3:63,833,870-63,864,484 (from NCBI)

This gene has 7 transcripts (splice variants) and 238 orthologues. Ubiquitous expression in adrenal (RPKM 20.0), colon (RPKM 19.8) and 25 other tissues.

功能概要

预测启用 RNA 结合活性。参与细胞核的 mRNA 输出和宿主细胞核的病毒 mRNA 输出。位于胞质溶胶和核斑点。转录输出复合体的 THO 复合体的一部分。与染色体、端粒区域共定位。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable RNA binding activity. Involved in mRNA export from nucleus and viral mRNA export from host cell nucleus. Located in cytosol and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]

THOC7 基因产物(3)

mRNA Protein Name
NM_001285387.3 NP_001272316.1 THO complex subunit 7 homolog isoform 2
NM_001285404.2 NP_001272333.1 THO complex subunit 7 homolog isoform 2
NM_025075.4 NP_079351.2 THO complex subunit 7 homolog isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12951069 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA export from nucleus IDA
IDA: 通过直接分析推断
17190602 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of THO complex IDA
IDA: 通过直接分析推断
15998806 GOA
part of THO complex part of transcription export complex IDA
IDA: 通过直接分析推断
15998806 GOA
colocalizes with chromosome, telomeric region IDA
IDA: 通过直接分析推断
24270157 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
12951069 GOA
located in nucleus IDA
IDA: 通过直接分析推断
12951069 GOA
part of transcription export complex IDA
IDA: 通过直接分析推断
15833825 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

THOC7 蛋白结构

THOC7

THOC7: Tho complex subunit 7 (7 - 140)

  • 0
  • 100
  • 204 a.a.
蛋白主名 其他名称

THO complex subunit 7 homolog

NIF3L1-binding protein 1

THOC7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
THOC7 Q6I9Y2 CCDC146 Homo sapiens Q8IYE0
Validated Y2H
32296183
种属内
THOC7 Q6I9Y2 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
种属内
THOC7 Q6I9Y2 THOC5 Homo sapiens Q13769
Anti Tag CoIP
26496610
种属内
THOC7 Q6I9Y2 THOC5 Homo sapiens Q13769
Anti Tag CoIP
19059247
种属内
THOC7 Q6I9Y2 THOC5 Homo sapiens Q13769
Pull Down
19059247
种属内
THOC7 Q6I9Y2 MNS1 Homo sapiens Q8NEH6
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ogden Syndrome

OGDNS

N-Terminal Acetyltransferase Deficiency

NATD

N-Alpha-Acetyltransferase

X-Linked Malformation And Infantile Lethality Syndrome

Premature Aging Appearance-Developmental Delay-Cardiac Arrhythmia Syndrome
Microphthalmia, Syndromic 1

MCOPS1

Lenz Microphthalmia Syndrome

Lenz Dysplasia

Mcops4

Syndromic Microphthalmia 1

Lenz Microphthalmia

Maa

Microphthalmia Or Anophthalmos With Associated Anomalies

Syndromic Microphthalmia Type 4

Microphthalmia, Syndromic 4

Microphthalmia, Syndromic 4, Formerly

Mcops4, Formerly

Anop1, Formerly

Maa, Formerly

Lenz Type Microphthalmia

Syndromic Microphthalmia 4

Microphthalmia Lenz Type

Microphthalmia Syndromic 1

Syndromic Microphthalmia Type 1

Microphthalmia Syndromic 4

Microphthalmia With Ankyloblepharon And Intellectual Disability

Microphthalmia, Lenz Type

Microphthalmia-Ankyloblepharon-Intellectual Disability Syndrome

Microphthalmia, Syndromic, 1

Anop1

Microphthalmia, Syndromic, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14496 THOC7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta THOC7 VGNC VGNC:79824
Rattus norvegicus THOC7 RGD RGD:1305475
Bos taurus THOC7 VGNC VGNC:106977
Felis catus THOC7 VGNC VGNC:66169
Mus musculus THOC7 MGD MGI:1913481
Canis familiaris THOC7 VGNC VGNC:58337
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