2. Gene
  3. MIPOL1 - mirror-image polydactyly 1 Gene

MIPOL1 - mirror-image polydactyly 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：镜样多指畸形 1

种属: Homo sapiens

同用名: CCDC193

基因 ID: 145282 | 基因类型: protein coding

关于 MIPOL1

Cytogenetic location: 14q13.3-q21.1 Genomic coordinates (GRCh38): 14:37,197,937-37,585,618 (from NCBI)

This gene has 30 transcripts (splice variants) and 177 orthologues. Broad expression in prostate (RPKM 1.7), testis (RPKM 0.6) and 20 other tissues.

功能概要

该基因编码含有卷曲螺旋结构域的蛋白质。所编码的蛋白质可能起到肿瘤抑制因子的作用。导致由该位点编码的蛋白质截断的易位与镜像多指畸形有关，也称为 Laurin-Sandrow 综合症。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2010 年 9 月]

This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]

MIPOL1 基因产物(14)

mRNA Protein Name
NM_001195296.2 NP_001182225.1 mirror-image polydactyly gene 1 protein isoform 1
NM_001195297.2 NP_001182226.1 mirror-image polydactyly gene 1 protein isoform 1
NM_001388067.1 NP_001374996.1 mirror-image polydactyly gene 1 protein isoform 1
NM_001388068.1 NP_001374997.1 mirror-image polydactyly gene 1 protein isoform 1
NM_001388069.1 NP_001374998.1 mirror-image polydactyly gene 1 protein isoform 2
NM_001388070.1 NP_001374999.1 mirror-image polydactyly gene 1 protein isoform 3
NM_001388071.1 NP_001375000.1 mirror-image polydactyly gene 1 protein isoform 3
NM_001388072.1 NP_001375001.1 mirror-image polydactyly gene 1 protein isoform 3
NM_001388073.1 NP_001375002.1 mirror-image polydactyly gene 1 protein isoform 4
NM_001388074.1 NP_001375003.1 mirror-image polydactyly gene 1 protein isoform 5
NM_001388075.1 NP_001375004.1 mirror-image polydactyly gene 1 protein isoform 5
NM_001388077.1 NP_001375006.1 mirror-image polydactyly gene 1 protein isoform 6
NM_001412440.1 NP_001399369.1 mirror-image polydactyly gene 1 protein isoform 7
NM_138731.7 NP_620059.1 mirror-image polydactyly gene 1 protein isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19667180 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mirror-image polydactyly gene 1 protein

MIPOL1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MIPOL1 Q8TD10 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra MIPOL1 Q8TD10 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 ZGPAT Homo sapiens Q8N5A5-2
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 ZGPAT Homo sapiens Q8N5A5-2
Y2H Array
25416956
Intra MIPOL1 Q8TD10 RTP5 Homo sapiens Q14D33
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 FBF1 Homo sapiens Q8TES7-6
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 FBF1 Homo sapiens Q8TES7-6
Y2H Array
25416956
Intra MIPOL1 Q8TD10 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 TTC12 Homo sapiens Q9H892-2
Y2H Prey Pooling
26871637
Intra MIPOL1 Q8TD10 TTC12 Homo sapiens Q9H892-2
Validated Y2H
26871637
Intra MIPOL1 Q8TD10 TTC12 Homo sapiens Q9H892-2
Y2H Array
25416956
Intra MIPOL1 Q8TD10 TTC12 Homo sapiens Q9H892-2
Y2H Array
26871637
Intra MIPOL1 Q8TD10 SSX3 Homo sapiens Q99909
Y2H Array
31515488
Intra MIPOL1 Q8TD10 SSX3 Homo sapiens Q99909
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 SSX3 Homo sapiens Q99909
Y2H Array
25416956
Intra MIPOL1 Q8TD10 PBX4 Homo sapiens Q9BYU1
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 PBX4 Homo sapiens Q9BYU1
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 PBX4 Homo sapiens Q9BYU1
Y2H Array
32296183
Intra MIPOL1 Q8TD10 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 MAGEA6 Homo sapiens P43360
Y2H Array
32296183
Intra MIPOL1 Q8TD10 MAGEA6 Homo sapiens P43360
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra MIPOL1 Q8TD10 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 PPP1R13B Homo sapiens Q96KQ4
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
25416956
Intra MIPOL1 Q8TD10 FAM124B Homo sapiens Q9H5Z6-2
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 SNAP91 Homo sapiens O60641-3
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 SNAP91 Homo sapiens O60641-3
Y2H Array
32296183
Intra MIPOL1 Q8TD10 PRPF31 Homo sapiens Q8WWY3
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 SNTG2 Homo sapiens Q9NY99-2
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 SNTG2 Homo sapiens Q9NY99-2
Y2H Array
32296183
Intra MIPOL1 Q8TD10 SNTG2 Homo sapiens Q9NY99-2
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 HAUS1 Homo sapiens Q96CS2
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 HAUS1 Homo sapiens Q96CS2
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 NEBL Homo sapiens O76041
Y2H Array
25416956
Intra MIPOL1 Q8TD10 TXN2 Homo sapiens Q99757
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 KIAA1328 Homo sapiens Q86T90
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 KIAA1328 Homo sapiens Q86T90
Y2H Array
32296183
Intra MIPOL1 Q8TD10 ZGPAT Homo sapiens Q8N5A5
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 ATP5PO Homo sapiens P48047
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 ATP5PO Homo sapiens P48047
Y2H Array
25416956
Intra MIPOL1 Q8TD10 MCM7 Homo sapiens P33993
Y2H Array
25416956
Intra MIPOL1 Q8TD10 MCM7 Homo sapiens P33993
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 CCT3 Homo sapiens P49368
Y2H Array
25416956
Intra MIPOL1 Q8TD10 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 BYSL Homo sapiens Q13895
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 TSEN15 Homo sapiens Q8WW01
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 GADD45GIP1 Homo sapiens Q8TAE8
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 EIF4E2 Homo sapiens O60573
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 EIF4E2 Homo sapiens O60573
Y2H Array
25416956
Intra MIPOL1 Q8TD10 SMARCE1 Homo sapiens Q969G3
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 SMARCE1 Homo sapiens Q969G3
Y2H Array
25416956
Intra MIPOL1 Q8TD10 UBE2K Homo sapiens P61086
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 UBE2K Homo sapiens P61086
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 ANKRD23 Homo sapiens Q86SG2
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 ANKRD23 Homo sapiens Q86SG2
Y2H Array
32296183
Intra MIPOL1 Q8TD10 MYLIP Homo sapiens Q8WY64
Y2H Array
25416956
Intra MIPOL1 Q8TD10 MYLIP Homo sapiens Q8WY64
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 FAM161A Homo sapiens Q3B820
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 FAM161B Homo sapiens Q96MY7
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 STMN3 Homo sapiens Q9NZ72
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 STMN3 Homo sapiens Q9NZ72
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 STMN3 Homo sapiens Q9NZ72
Y2H Array
32296183
Intra MIPOL1 Q8TD10 LENG1 Homo sapiens Q96BZ8
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 RBM41 Homo sapiens Q96IZ5
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 RBM41 Homo sapiens Q96IZ5
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 RBM41 Homo sapiens Q96IZ5
Y2H Array
25416956
Intra MIPOL1 Q8TD10 TCHP Homo sapiens Q9BT92
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 TCHP Homo sapiens Q9BT92
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 MMTAG2 Homo sapiens Q9BU76
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 RCOR3 Homo sapiens Q9P2K3
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 CCDC120 Homo sapiens Q96HB5
Y2H Array
32296183
Intra MIPOL1 Q8TD10 CCDC120 Homo sapiens Q96HB5
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 CCDC120 Homo sapiens Q96HB5
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 BEX2 Homo sapiens Q9BXY8
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 BEX2 Homo sapiens Q9BXY8
Y2H Array
25416956
Intra MIPOL1 Q8TD10 CDK18 Homo sapiens Q07002
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 CDK18 Homo sapiens Q07002
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 CDK18 Homo sapiens Q07002
Y2H Array
25416956
Intra MIPOL1 Q8TD10 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra MIPOL1 Q8TD10 PAX6 Homo sapiens P26367
Y2H Array
32296183
Intra MIPOL1 Q8TD10 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 UTP25 Homo sapiens Q68CQ4
Validated Y2H
25416956
Intra MIPOL1 Q8TD10 UTP25 Homo sapiens Q68CQ4
Y2H Array
29892012
Intra MIPOL1 Q8TD10 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 EAF1 Homo sapiens Q96JC9
Y2H Prey Pooling
25416956
Intra MIPOL1 Q8TD10 DAXX Homo sapiens Q9UER7
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 KIF9 Homo sapiens Q9HAQ2
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Intra MIPOL1 Q8TD10 TTC23 Homo sapiens Q5W5X9-3
Y2H Array
32296183
Intra MIPOL1 Q8TD10 TTC23 Homo sapiens Q5W5X9-3
Y2H Prey Pooling
32296183
Intra MIPOL1 Q8TD10 USH1C Homo sapiens Q9Y6N9
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Polydactyly

Non-Syndromic Polydactyly

Polydactyly, Postaxial

Postaxial Polydactyly

Supernumerary Digit

Extra Digits

Hyperdactyly

Polydactylia

Polydactylism

Supernumerary Digits
Laurin-Sandrow Syndrome

Sandrow Syndrome

Tetramelic Mirror-Image Polydactyly

Mirror-Image Polydactyly

Mirror Hands And Feet With Nasal Defects

Tmip

LSS

Mip

Mirror Hands And Feets-Nasal Defects Syndrome

Fibula And Ulna, Duplication Of, With Absence Of Tibia And Radius

Miccor Hands And Feet With Nasal Defects

Mipduplication Of Fibuland Ulna With Absence Of Tibia And Radius

Fibula Ulna Duplication Tibia Radius Absence

Laurin Sandrow Syndrome

Duplication Of Fibula And Ulna With Absence Of Tibia And Radius

Segmental Laurin-Sandrow Syndrome

Laurin-Sandrow Syndrome, Segmental
Bronchus Adenoma

Bronchial Adenoma

Adenoma Of The Bronchus
Acute Laryngitis

Acute Laryngitis Nos

Laryngeal Inflammation

Laryngitis Nos

Larynx Inflammation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08462 MIPOL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MIPOL1 VGNC VGNC:106823
Canis familiaris MIPOL1 VGNC VGNC:43243
Felis catus MIPOL1 VGNC VGNC:80911
Rattus norvegicus MIPOL1 RGD RGD:6504372
Mus musculus MIPOL1 MGD MGI:1920740
Macaca mulatta MIPOL1 VGNC VGNC:74801
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