1. Gene
  2. RCOR3 - REST corepressor 3 Gene

RCOR3 - REST corepressor 3 Gene

中文名称:REST 核心阻遏物 3

种属: Homo sapiens

基因 ID: 55758 | 基因类型: protein coding

关于 RCOR3

This gene has 16 transcripts (splice variants), 191 orthologues and 5 paralogues. Ubiquitous expression in testis (RPKM 13.7), thyroid (RPKM 11.6) and 25 other tissues.

功能概要

预测启用酶结合活性和转录辅阻遏物活性。预计参与组蛋白去乙酰化;转录的负调控,DNA 模板化; RNA 聚合酶 II 对转录的调控。位于细胞质和核质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable Enzyme binding activity and transcription corepressor activity. Predicted to be involved in histone deacetylation; negative regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RCOR3 基因产物(6)

mRNA Protein Name
NM_001136223.3 NP_001129695.1 REST corepressor 3 isoform a
NM_001136224.4 NP_001129696.2 REST corepressor 3 isoform b
NM_001136225.3 NP_001129697.1 REST corepressor 3 isoform c
NM_001350069.2 NP_001336998.1 REST corepressor 3 isoform e
NM_001350070.2 NP_001336999.1 REST corepressor 3 isoform f
NM_018254.5 NP_060724.1 REST corepressor 3 isoform d
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RCOR3 蛋白结构

ELM2

ELM2: ELM2 domain (1 - 53)

Myb_DNA-binding

Myb_DNA-binding: Myb-like DNA-binding domain (289 - 332)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 495 a.a.
蛋白主名 其他名称

REST corepressor 3

RCOR3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RCOR3 Q9P2K3 CCDC102B Homo sapiens Q68D86
Y2H Array
25416956
Intra RCOR3 Q9P2K3 CCDC102B Homo sapiens Q68D86
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 CCDC102B Homo sapiens Q68D86
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
25416956
Intra RCOR3 Q9P2K3 NECAB2 Homo sapiens Q7Z6G3-2
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 LUZP4 Homo sapiens Q9P127
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 MAGEA6 Homo sapiens P43360
Y2H Array
25416956
Intra RCOR3 Q9P2K3 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 MAGEA6 Homo sapiens P43360
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 CDR2 Homo sapiens Q01850
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 CDR2 Homo sapiens Q01850
Y2H Array
25416956
Intra RCOR3 Q9P2K3 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 TRIM54 Homo sapiens Q9BYV2
Y2H Array
25416956
Intra RCOR3 Q9P2K3 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 MIPOL1 Homo sapiens Q8TD10
Y2H Array
25416956
Intra RCOR3 Q9P2K3 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 TRAF2 Homo sapiens Q12933
Y2H Array
25416956
Intra RCOR3 Q9P2K3 TRAF2 Homo sapiens Q12933
Y2H
21516116
Intra RCOR3 Q9P2K3 TXLNA Homo sapiens P40222
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Y2H Array
29892012
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Y2H Array
19060904
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Lumier
32814053
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Y2H Array
25416956
Intra RCOR3 Q9P2K3 GSE1 Homo sapiens Q14687
Y2H Pooling
19060904
Intra RCOR3 Q9P2K3 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 PRDM14 Homo sapiens Q9GZV8
Y2H Array
25416956
Intra RCOR3 Q9P2K3 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra RCOR3 Q9P2K3 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 LCA5 Homo sapiens Q86VQ0
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 LCA5 Homo sapiens Q86VQ0
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 NINL Homo sapiens Q9Y2I6
Y2H Array
25416956
Intra RCOR3 Q9P2K3 NINL Homo sapiens Q9Y2I6
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 KRT15 Homo sapiens P19012
Pull Down
16189514
Intra RCOR3 Q9P2K3 KRT15 Homo sapiens P19012
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 TSGA10 Homo sapiens Q9BZW7
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
25416956
Intra RCOR3 Q9P2K3 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
25416956
Intra RCOR3 Q9P2K3 IKZF3 Homo sapiens Q9UKT9
Y2H Array
25416956
Intra RCOR3 Q9P2K3 CEP55 Homo sapiens Q53EZ4
Y2H Array
25416956
Intra RCOR3 Q9P2K3 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra RCOR3 Q9P2K3 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa 29

RP29

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RCOR3 RGD RGD:1593864
Bos taurus RCOR3 VGNC VGNC:33836
Mus musculus RCOR3 MGD MGI:2441920
Macaca mulatta RCOR3 VGNC VGNC:76824
Felis catus RCOR3 VGNC VGNC:64553
Canis familiaris RCOR3 VGNC VGNC:45448