2. Gene
  3. IKZF3 - IKAROS family zinc finger 3 Gene

IKZF3 - IKAROS family zinc finger 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：IKAROS 家族锌指 3

种属: Homo sapiens

同用名: AIO; IMD84; AIOLOS; ZNFN1A3

基因 ID: 22806 | 基因类型: protein coding

关于 IKZF3

Cytogenetic location: 17q12-q21.1 Genomic coordinates (GRCh38): 17:39,757,715-39,864,312 (from NCBI)

This gene has 17 transcripts (splice variants), 133 orthologues, 11 paralogues and is associated with 71 phenotypes. Biased expression in lymph node (RPKM 17.4), spleen (RPKM 11.5) and 10 other tissues.

功能概要

该基因编码锌指蛋白 Ikaros 家族的一个成员。该蛋白家族的三个成员 (Ikaros、Aiolos 和 Helios) 是参与淋巴细胞发育调节的造血特异性转录因子。该基因产物是一种转录因子，在调节 B 淋巴细胞增殖和分化中起重要作用。 Ikaros 和 Aiolos 都可以参与染色质重塑。 Aiolos 对 B 淋巴细胞基因表达的调节很复杂，因为它似乎需要依次形成 Ikaros 同二聚体、Ikaros/Aiolos 异二聚体和 Aiolos 同二聚体。已经描述了几种编码不同亚型的替代转录物，以及一些非蛋白质编码变体。[RefSeq 提供，2012 年 4 月]

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

IKZF3 基因产物(16)

mRNA Protein Name
NM_001257408.2 NP_001244337.1 zinc finger protein Aiolos isoform 7
NM_001257409.2 NP_001244338.1 zinc finger protein Aiolos isoform 8
NM_001257410.2 NP_001244339.1 zinc finger protein Aiolos isoform 9
NM_001257411.2 NP_001244340.1 zinc finger protein Aiolos isoform 10
NM_001257412.2 NP_001244341.1 zinc finger protein Aiolos isoform 11
NM_001257413.2 NP_001244342.1 zinc finger protein Aiolos isoform 12
NM_001257414.2 NP_001244343.1 zinc finger protein Aiolos isoform 13
NM_001284514.2 NP_001271443.1 zinc finger protein Aiolos isoform 14
NM_001284515.2 NP_001271444.1 zinc finger protein Aiolos isoform 14
NM_001284516.1 NP_001271445.1 zinc finger protein Aiolos isoform 14
NM_012481.5 NP_036613.2 zinc finger protein Aiolos isoform 1
NM_183228.3 NP_899051.1 zinc finger protein Aiolos isoform 2
NM_183229.3 NP_899052.1 zinc finger protein Aiolos isoform 3
NM_183230.3 NP_899053.1 zinc finger protein Aiolos isoform 4
NM_183231.3 NP_899054.1 zinc finger protein Aiolos isoform 5
NM_183232.3 NP_899055.1 zinc finger protein Aiolos isoform 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
34155405 GOA
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
17646674 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
17646674 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10369681 GOA
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
34155405 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
17646674 GOA
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
34155405 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
10369681 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10369681 GOA
located in nucleus IDA
IDA: 通过直接分析推断
10369681 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IKZF3 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (133 - 156)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (160 - 182)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (189 - 212)

  • 0
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  • 400
  • 509 a.a.
蛋白主名 其他名称

zinc finger protein Aiolos

zinc finger DNA binding protein Aiolos

IKZF3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
IKZF3 Q9UKT9 FBF1 Homo sapiens Q8TES7-6
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 POLM Homo sapiens Q6PIY2
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 POLM Homo sapiens Q6PIY2
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 OAZ3 Homo sapiens Q9UMX2
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Validated Y2H
27107012
种属内
IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 CABP5 Homo sapiens Q9NP86
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 PCID2 Homo sapiens Q5JVF3
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 PCID2 Homo sapiens Q5JVF3
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Validated Y2H
27107012
种属内
IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Validated Y2H
27107012
种属内
IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 GOLGA6A Homo sapiens Q9NYA3
Y2H Array
32296183
种属内
IKZF3 Q9UKT9 GOLGA6A Homo sapiens Q9NYA3
Y2H Prey Pooling
32296183
种属内
IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H
21516116
种属内
IKZF3 Q9UKT9 PRKAA1 Homo sapiens Q13131
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PRKAA1 Homo sapiens Q13131
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2-2
Validated Y2H
32296183
种属内
IKZF3 Q9UKT9 IKZF4 Homo sapiens Q9H2S9
Anti Tag CoIP
33961781
种属内
IKZF3 Q9UKT9 CHCHD2 Homo sapiens Q9Y6H1
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 CHCHD2 Homo sapiens Q9Y6H1
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
种属内
IKZF3 Q9UKT9 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
种属内
IKZF3 Q9UKT9 ZMYM2 Homo sapiens Q9UBW7
Y2H Prey Pooling
32296183
种属内
IKZF3 Q9UKT9 ZMYM2 Homo sapiens Q9UBW7
Y2H Array
32296183
种属内
IKZF3 Q9UKT9 CDK4 Homo sapiens P11802
Y2H Prey Pooling
32296183
种属内
IKZF3 Q9UKT9 CDK4 Homo sapiens P11802
Y2H Array
32296183
种属内
IKZF3 Q9UKT9 ZGPAT Homo sapiens Q8N5A5
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 PIK3R2 Homo sapiens O00459
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 PIK3R2 Homo sapiens O00459
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 ABLIM3 Homo sapiens O94929
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
种属内
IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
种属内
IKZF3 Q9UKT9 EMC2 Homo sapiens Q15006
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 EMC2 Homo sapiens Q15006
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 EXOSC5 Homo sapiens Q9NQT4
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 EXOSC5 Homo sapiens Q9NQT4
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 CDKN1A Homo sapiens P38936
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 CDKN1A Homo sapiens P38936
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Validated Y2H
27107012
种属内
IKZF3 Q9UKT9 RHOA Homo sapiens P61586
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 ING5 Homo sapiens Q8WYH8
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 ING5 Homo sapiens Q8WYH8
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 PIN1 Homo sapiens Q13526
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TLE5 Homo sapiens Q08117
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 NEK6 Homo sapiens Q9HC98
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 NEK6 Homo sapiens Q9HC98
Y2H Array
29892012
种属内
IKZF3 Q9UKT9 EXOC8 Homo sapiens Q8IYI6
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 EXOC8 Homo sapiens Q8IYI6
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 KRT19 Homo sapiens P08727
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
种属内
IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
27107012
种属内
IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 RCOR3 Homo sapiens Q9P2K3
Y2H
21516116
种属内
IKZF3 Q9UKT9 TRAPPC6A Homo sapiens O75865
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TRAPPC6A Homo sapiens O75865
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 GEM Homo sapiens P55040
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 GEM Homo sapiens P55040
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 NME7 Homo sapiens Q9Y5B8
Validated Y2H
32296183
种属内
IKZF3 Q9UKT9 STAMBPL1 Homo sapiens Q96FJ0
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 AQP1 Homo sapiens P29972
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 AQP1 Homo sapiens P29972
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H
21516116
种属内
IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 MAGOHB Homo sapiens Q96A72
Y2H
21516116
种属内
IKZF3 Q9UKT9 MAGOHB Homo sapiens Q96A72
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 STK16 Homo sapiens O75716
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2
Y2H
21516116
种属内
IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Y2H
21516116
种属内
IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 AIRIM Homo sapiens Q9NX04
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 NATD1 Homo sapiens Q8N6N6
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
29892012
种属内
IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 TSTD2 Homo sapiens Q5T7W7
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 TSTD2 Homo sapiens Q5T7W7
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 OSGIN1 Homo sapiens Q9UJX0
Y2H Array
31515488
种属内
IKZF3 Q9UKT9 OSGIN1 Homo sapiens Q9UJX0
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 AKAP9 Homo sapiens Q99996-2
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 AKAP9 Homo sapiens Q99996-2
Validated Y2H
25416956
种属内
IKZF3 Q9UKT9 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
25416956
种属内
IKZF3 Q9UKT9 MORN3 Homo sapiens Q6PF18
Y2H Array
25416956
种属内
IKZF3 Q9UKT9 FOXP3 Homo sapiens Q9BZS1
Anti Tag CoIP
20676092
种属间: 跨种属相互作用 种属内: 同种属相互作用

IKZF3 抗体

目录号 产品名 应用 反应物种
HY-P82371 IKZF3 Antibody (YA2116) WB, IHC-P, ICC/IF, FC Human, Mouse, Rat

关联疾病

疾病名称 别名
Immunodeficiency 84

IMD84
Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos
Gestational Ovarian Choriocarcinoma
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Autosomal Recessive Intellectual Developmental Disorder

Mental Retardation, Autosomal Recessive

Autosomal Recessive Mental Retardation

Autosomal Recessive Non-Syndromic Mental Retardation

Autosomal Recessive Non-Syndromic Intellectual Disability
Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-161101 MG degrader 1 99.83% 否
HY-168614 MGD-4 Degrader / 否
HY-168615 MGD-28 Degrader / 否
HY-169077 IKZF3 degrader 1 Degrader / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IKZF3 RGD RGD:1307024
Felis catus IKZF3 VGNC VGNC:62900
Canis familiaris IKZF3 VGNC VGNC:41925
Mus musculus IKZF3 MGD MGI:1342542
Macaca mulatta IKZF3 VGNC VGNC:73587
Bos taurus IKZF3 VGNC VGNC:30104
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