2. Gene
  3. ABLIM3 - actin binding LIM protein family member 3 Gene

ABLIM3 - actin binding LIM protein family member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：肌动蛋白结合 LIM 蛋白家族成员 3

种属: Homo sapiens

同用名: HMFN1661

基因 ID: 22885 | 基因类型: protein coding

关于 ABLIM3

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:149,141,493-149,260,542 (from NCBI)

This gene has 12 transcripts (splice variants), 288 orthologues and 3 paralogues. Broad expression in fat (RPKM 33.5), heart (RPKM 19.5) and 14 other tissues.

功能概要

该基因编码肌动蛋白结合 LIM (abLIM) 蛋白家族的成员。这些蛋白质的特征在于一个 N 端 LIM 结构域和一个 C 端 dematin 样结构域。编码的蛋白质与肌动蛋白丝相互作用，可能是几种细胞类型中粘附连接的组成部分。该基因的一个变体可能与男性人类患者的疼痛敏感性有关。[RefSeq 提供，2016 年 9 月]

This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients. [provided by RefSeq, Sep 2016]

ABLIM3 基因产物(10)

mRNA Protein Name
NM_001301015.3 NP_001287944.1 actin-binding LIM protein 3 isoform 1
NM_001301018.3 NP_001287947.1 actin-binding LIM protein 3 isoform 2
NM_001301028.3 NP_001287957.1 actin-binding LIM protein 3 isoform 4
NM_001345858.2 NP_001332787.1 actin-binding LIM protein 3 isoform 5
NM_001345859.2 NP_001332788.1 actin-binding LIM protein 3 isoform 6
NM_001345860.2 NP_001332789.1 actin-binding LIM protein 3 isoform 7
NM_001345861.2 NP_001332790.1 actin-binding LIM protein 3 isoform 6
NM_001370417.1 NP_001357346.1 actin-binding LIM protein 3 isoform 2
NM_001370418.1 NP_001357347.1 actin-binding LIM protein 3 isoform 7
NM_014945.5 NP_055760.1 actin-binding LIM protein 3 isoform 1

ABLIM3 蛋白结构

LIM

LIM: LIM domain (23 - 76)

LIM

LIM: LIM domain (82 - 135)

LIM

LIM: LIM domain (151 - 206)

LIM

LIM: LIM domain (210 - 263)

VHP

VHP: Villin headpiece domain (648 - 683)

  • 0
  • 200
  • 400
  • 600
  • 683 a.a.
蛋白主名 其他名称

actin-binding LIM protein 3

abLIM-3

ABLIM3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ABLIM3 O94929 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
种属内
ABLIM3 O94929 IKZF3 Homo sapiens Q9UKT9
Y2H Array
31515488
种属内
ABLIM3 O94929 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
25416956
种属内
ABLIM3 O94929 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00108 ABLIM3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ABLIM3 VGNC VGNC:25509
Mus musculus ABLIM3 MGD MGI:2442582
Canis familiaris ABLIM3 VGNC VGNC:37480
Rattus norvegicus ABLIM3 RGD RGD:1565118
Felis catus ABLIM3 VGNC VGNC:59491
Macaca mulatta ABLIM3 VGNC VGNC:69546
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