2. Gene
  3. NINL - ninein like Gene

NINL - ninein like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：样

种属: Homo sapiens

同用名: NLP

基因 ID: 22981 | 基因类型: protein coding

关于 NINL

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:25,452,697-25,585,531 (from NCBI)

This gene has 7 transcripts (splice variants), 176 orthologues and 1 paralogue. Broad expression in kidney (RPKM 4.4), ovary (RPKM 3.4) and 23 other tissues.

功能概要

预测可启用钙离子结合活性。预计参与中心体的微管锚定。位于胞质溶胶中；细胞间桥；和微管细胞骨架。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity. Predicted to be involved in microtubule anchoring at centrosome. Located in cytosol; intercellular bridge; and microtubule Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

NINL 基因产物(2)

mRNA Protein Name
NM_001318226.2 NP_001305155.1 ninein-like protein isoform 2
NM_025176.6 NP_079452.3 ninein-like protein isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
26485514 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NINL 蛋白结构

EF-hand_8

EF-hand_8: EF-hand domain pair (226 - 259)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1382 a.a.
蛋白主名 其他名称

ninein-like protein

NINL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NINL Q9Y2I6 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
25416956
Intra NINL Q9Y2I6 CCDC146 Homo sapiens Q8IYE0-2
Y2H Array
25416956
Intra NINL Q9Y2I6 HAUS1 Homo sapiens Q96CS2
Y2H Prey Pooling
25416956
Intra NINL Q9Y2I6 KAT5 Homo sapiens Q92993
Y2H Prey Pooling
25416956
Intra NINL Q9Y2I6 KAT5 Homo sapiens Q92993
Y2H Array
25416956
Intra NINL Q9Y2I6 FAM161A Homo sapiens Q3B820
Validated Y2H
25416956
Intra NINL Q9Y2I6 RBM41 Homo sapiens Q96IZ5
Validated Y2H
25416956
Intra NINL Q9Y2I6 RBM41 Homo sapiens Q96IZ5
Y2H Array
25416956
Intra NINL Q9Y2I6 RCOR3 Homo sapiens Q9P2K3
Validated Y2H
25416956
Intra NINL Q9Y2I6 RCOR3 Homo sapiens Q9P2K3
Y2H Pooling
16189514
Intra NINL Q9Y2I6 SH2D4A Homo sapiens Q9H788
Validated Y2H
25416956
Intra NINL Q9Y2I6 L3MBTL4 Homo sapiens Q8NA19
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Trichostrongylosis

Trichostrongyliasis

Infection By Trichostrongylus

Infection By Trichostrongylus Species

Trichostrongylus Infestation
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Hodgkin'S Lymphoma, Lymphocytic-Histiocytic Predominance

Hodgkin Disease

Hodgkin Lymphoma, Lymphocyte-Rich

Hodgkin Lymphoma, Lymphocytic-Histiocytic Predominance

Hodgkin'S Disease, Lymphocyte Predominance

Lymphocyte Rich Hodgkin'S Disease

Lymphocyte Rich Classical Hodgkin Lymphoma
Trichostrongyloidiasis
Hypotrichosis 1

HYPT1

Hhs

Hts

Hypotrichosis Simplex

Hypotrichosis Simplex, Generalized, Hereditary

Hereditary Generalized Hypotrichosis Simplex

Generalized Hypothricosis Simplex

Hypotrichosis Simplex Hereditary

Hypotrichosis, Type 1
Cone-Rod Dystrophy 2

Cone-Rod Dystrophy

CORD2

Cone-Rod Retinal Dystrophy

Rcrd2

Cone-Rod Retinal Dystrophy 2

Crd2

Cord

Crd

Retinal Cone-Rod Dystrophy

Cone-Rod Retinal Dystrophy-2

Retinal Cone-Rod Dystrophy 2

Tapetoretinal Degeneration

Cone-Rod Degeneration

Cone Rod Dystrophy

Dystrophy, Cone-Rod

Dystrophy, Cone-Rod, Type 2

Retinitis Pigmentosa

Retinitis Pigmentosa 2

Progressive Cone-Rod Dystrophy
Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09300 NINL Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus NINL MGD MGI:1925427
Macaca mulatta NINL VGNC VGNC:75273
Felis catus NINL VGNC VGNC:63805
Canis familiaris NINL VGNC VGNC:43813
Rattus norvegicus NINL RGD RGD:1306152
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