CCT3 - chaperonin containing TCP1 subunit 3 Gene

中文名称：含伴侣蛋白的 TCP1 亚基 3

种属: Homo sapiens

同用名: CCTG; PIG48; TRIC5; CCT-gamma; TCP-1-gamma

关于 CCT3

功能概要

该基因编码的蛋白质是一种分子伴侣，它是含有伴侣蛋白的 TCP1 复合物 (CCT) 的成员，也称为 TCP1 环状复合物 (TRiC) 。该复合物由两个相同的堆叠环组成，每个环包含八种不同的蛋白质。未折叠的多肽进入复合物的中央空腔，并以依赖 ATP 的方式折叠。该复合物折叠各种蛋白质，包括肌动蛋白和微管蛋白。已经表征了该基因的替代转录剪接变体。此外，在 8 号染色体上发现了该基因的假基因。[RefSeq 提供，2010 年 8 月]

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]