2. Gene
  3. PDCL - phosducin like Gene

PDCL - phosducin like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：光导蛋白样

种属: Homo sapiens

同用名: PhLP

基因 ID: 5082 | 基因类型: protein coding

关于 PDCL

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:122,818,097-122,828,588 (from NCBI)

This gene has 3 transcripts (splice variants), 201 orthologues and 4 paralogues. Ubiquitous expression in endometrium (RPKM 5.5), lung (RPKM 5.2) and 25 other tissues.

功能概要

Phosducin 样蛋白是异源三聚体 G 蛋白的推定调节剂。该蛋白质与 phosducin 具有广泛的氨基酸序列同源性，phosducin 是一种在视网膜和松果体中表达的磷蛋白。 phosducin 样蛋白和 phosducin 均已显示通过与 G 蛋白的 β-γ 亚基结合来调节 G 蛋白信号传导。[RefSeq 提供，2008 年 7 月]

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

PDCL 基因产物(1)

mRNA Protein Name
NM_005388.5 NP_005379.3 phosducin-like protein
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PDCL 蛋白结构

Phosducin

Phosducin: Phosducin (36 - 299)

  • 0
  • 100
  • 200
  • 301 a.a.
蛋白主名 其他名称

phosducin-like protein

PDCL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PDCL Q13371 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra PDCL Q13371 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra PDCL Q13371 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra PDCL Q13371 PSMC5 Homo sapiens P62195
Lumier
32814053
Intra PDCL Q13371 PSMC5 Homo sapiens P62195
Y2H
21516116
Intra PDCL Q13371 PSMC5 Homo sapiens P62195
Y2H Array
29892012
Intra PDCL Q13371 MRPL11 Homo sapiens Q9Y3B7
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pollen Allergy

Hay Fever
Timothy Grass Allergy
Thunderstorm Triggered Asthma

Thunderstorm Asthma

Thunderstorm Related Asthma
Tomato Allergy

Solanum Lycopersicum Fruit Allergy
Melon Allergy

Cucumis Melo Fruit Allergy
Orange Allergy

Citrus Sinensis Fruit Allergy
Apple Allergy

Malus Domestica Fruit Allergy
Peach Allergy

Prunus Persica Fruit Allergy
Vegetable Allergy
Latex Allergy
Fruit Allergy

Allergy To Fruit
Fish Allergy

Allergy To Fish
Crustacean Allergy
Shrimp Allergy
Respiratory Allergy

Airway Allergy
Legume Allergy

Fabaceae Allergy
Wheat Allergy

Wheat Allergic Reaction

Wheat Hypersensitivity

Allergy To Wheat

Allergy Wheat
Nut Allergy

Nut Allergic Reaction

Nut Hypersensitivity

Allergy To Nuts

Allergy Nut
Nasal Cavity Disease

Disorder Of Nasal Cavity
Peanut Allergy

Allergy To Peanuts

Peanut Allergic Reaction

Allergies Peanut

Peanut Hypersensitivity
Nose Disease

Nose Diseases

Disorder Of The Nose

Nasal Disorder

Abnormality Of The Nose
Celery Allergy
Vernal Conjunctivitis

Conjunctivitis Vernal

Conjunctivitis, Vernal
Egg Allergy

Allergy To Eggs

Allergies Egg

Egg Hypersensitivity
Status Asthmaticus

Asthma With Status Asthmaticus

Severe Asthma Attack
Chronic Rhinitis

Rhinitis - Chronic

Chronic Rhinitis Nos

Rhinitis

Rhinitis Nos
Food Allergy

Food Hypersensitivity

Food Allergies

Allergy Food

Food Allergen-Induced Hypersensitivity
Intermittent Asthma
Conjunctival Disease

Conjunctival Diseases

Conjunctival Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10196 PDCL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10197 PDCL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10198 PDCL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PDCL VGNC VGNC:75907
Mus musculus PDCL MGD MGI:1914716
Felis catus PDCL VGNC VGNC:68750
Canis familiaris PDCL VGNC VGNC:44342
Rattus norvegicus PDCL RGD RGD:621135
Bos taurus PDCL VGNC VGNC:32665
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