VPS52 - VPS52 subunit of GARP complex Gene

中文名称：GARP 复合体的 VPS52 亚基

种属: Homo sapiens

同用名: ARE1; SAC2; SACM2L; dJ1033B10.5

关于 VPS52

功能概要

该基因编码的蛋白质类似于肌动蛋白突变 2 基因的酵母抑制因子。酵母蛋白形成四聚体高尔基体相关逆行蛋白复合物的一个亚基，该复合物参与从早期和晚期内体到反式高尔基体网络的囊泡运输。该基因位于 6 号染色体上，与编码核糖体蛋白 S18 的基因呈头对头方向。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 1 月]

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]