GORASP2 - golgi reassembly stacking protein 2 Gene

中文名称：高尔基重组堆积蛋白 2

种属: Homo sapiens

同用名: p59; GRS2; GOLPH6; GRASP55

关于 GORASP2

功能概要

该基因编码高尔基重组堆积蛋白家族的一个成员。这些蛋白质可能在高尔基体池的堆积和高尔基体带的形成以及细胞凋亡或有丝分裂过程中的高尔基体碎裂中发挥作用。编码的蛋白质还在转化生长因子 α 的细胞内转运中发挥作用，并可能作为分子伴侣发挥作用。该基因的假基因位于 2 号染色体的短臂上。已观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 1 月]

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during Apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]