1. Gene
  2. ALKBH4 - alkB homolog 4, lysine demethylase Gene

ALKBH4 - alkB homolog 4, lysine demethylase Gene

种属: Homo sapiens (human)

同用名: ABH4

基因 ID: 54784 | 基因类型: protein coding

关于 ALKBH4

功能概要

Enables 2-oxoglutarate-dependent dioxygenase activity and actin binding activity. Involved in actomyosin structure organization; cleavage furrow ingression; and protein demethylation. Located in contractile ring and midbody. [provided by Alliance of Genome Resources, Apr 2022]

ALKBH4 基因产物(1)

mRNA Protein Name
NM_017621.4 NP_060091.1 alpha-ketoglutarate-dependent dioxygenase alkB homolog 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 2-oxoglutarate-dependent dioxygenase activity IDA
IDA: 通过直接分析推断
21166655 GOA
enables actin binding IDA
IDA: 通过直接分析推断
23673617 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actomyosin structure organization IMP
IMP: 通过突变表型推断
23673617 GOA
involved in cleavage furrow ingression IMP
IMP: 通过突变表型推断
23673617 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in contractile ring IDA
IDA: 通过直接分析推断
23673617 GOA
located in midbody IDA
IDA: 通过直接分析推断
23673617 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

DNA N6-methyl adenine demethylase ALKBH4

alkB homolog 4, lysine demthylase

alkB, alkylation repair homolog 4

alkylated DNA repair protein alkB homolog 4

lysine-specific demethylase ALKBH4

probable alpha-ketoglutarate-dependent dioxygenase ABH4

ALKBH4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ALKBH4 Q9NXW9 TXNL4B Homo sapiens Q9NX01
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 TXNL4B Homo sapiens Q9NX01
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 LCN2 Homo sapiens P80188
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 LCN2 Homo sapiens P80188
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 FAM168A Homo sapiens Q92567-2
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 FAM168A Homo sapiens Q92567-2
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 MLLT3 Homo sapiens P42568
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 MLLT3 Homo sapiens P42568
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 MLLT3 Homo sapiens P42568
Confocal
23145062
Intra ALKBH4 Q9NXW9 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 DTX2 Homo sapiens Q86UW9
Y2H Array
25416956
Intra ALKBH4 Q9NXW9 DTX2 Homo sapiens Q86UW9
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 DTX2 Homo sapiens Q86UW9
Y2H Prey Pooling
25416956
Intra ALKBH4 Q9NXW9 DTX2 Homo sapiens Q86UW9
Validated Y2H
25416956
Intra ALKBH4 Q9NXW9 DTX2 Homo sapiens Q86UW9
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 NIF3L1 Homo sapiens Q9GZT8
Y2H Array
32296183
Intra ALKBH4 Q9NXW9 NIF3L1 Homo sapiens Q9GZT8
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 BPIFA1 Homo sapiens Q9NP55
Y2H Prey Pooling
32296183
Intra ALKBH4 Q9NXW9 BPIFA1 Homo sapiens Q9NP55
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用