2. Gene
  3. GNG7 - G protein subunit gamma 7 Gene

GNG7 - G protein subunit gamma 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白亚基γ7

种属: Homo sapiens

同用名: HG3B

基因 ID: 2788 | 基因类型: protein coding

关于 GNG7

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:2,511,219-2,702,694 (from NCBI)

This gene has 2 transcripts (splice variants), 178 orthologues and 11 paralogues. Ubiquitous expression in brain (RPKM 18.8), heart (RPKM 10.5) and 22 other tissues.

功能概要

预测启用 G 蛋白 β-亚基结合活性。预计参与 G 蛋白偶联受体信号通路和腺苷酸环化酶活性的调节。预计会在行为恐惧反应的上游或内部行动；运动行为；和受体鸟苷酸环化酶信号通路。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of Adenylate Cyclase activity. Predicted to act upstream of or within behavioral fear response; locomotory behavior; and receptor guanylyl cyclase signaling pathway. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

GNG7 基因产物(1)

mRNA Protein Name
NM_052847.3 NP_443079.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GNG7 蛋白结构

G-gamma

G-gamma: GGL domain (5 - 68)

  • 0
  • 68 a.a.
蛋白主名 其他名称

guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

guanine nucleotide binding protein (G protein), gamma 7

GNG7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GNG7 O60262 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
32296183
种属内
GNG7 O60262 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
32296183
种属内
GNG7 O60262 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05560 GNG7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus GNG7 VGNC VGNC:29468
Canis familiaris GNG7 VGNC VGNC:41322
Mus musculus GNG7 MGD MGI:95787
Rattus norvegicus GNG7 RGD RGD:61860
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z