2. Gene
  3. VPS37B - VPS37B subunit of ESCRT-I Gene

VPS37B - VPS37B subunit of ESCRT-I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：ESCRT-I 的 VPS37B 亚基

种属: Homo sapiens

基因 ID: 79720 | 基因类型: protein coding

关于 VPS37B

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:122,865,330-122,896,124 (from NCBI)

This gene has 4 transcripts (splice variants), 222 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 9.2), colon (RPKM 9.0) and 25 other tissues.

功能概要

启用钙依赖性蛋白质结合活性。通过宿主 ESCRT 复合体参与病毒出芽的正向调节。位于核内体膜；中体;和质膜。 ESCRT I 复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium-dependent protein binding activity. Involved in positive regulation of viral budding via host ESCRT complex. Located in endosome membrane; midbody; and plasma membrane. Part of ESCRT I complex. [provided by Alliance of Genome Resources, Apr 2022]

VPS37B 基因产物(1)

mRNA Protein Name
NM_024667.3 NP_078943.1 vacuolar protein sorting-associated protein 37B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
23924735 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15218037 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of viral budding via host ESCRT complex IMP
IMP: 通过突变表型推断
15218037 GOA
involved in viral release from host cell IMP
IMP: 通过突变表型推断
15218037 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ESCRT I complex IDA
IDA: 通过直接分析推断
18005716 GOA
part of ESCRT I complex IPI
IPI: 通过物理相互作用推断
18005716 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
15218037 GOA
located in endosome IDA
IDA: 通过直接分析推断
17940959 GOA
located in endosome membrane IDA
IDA: 通过直接分析推断
15218037 GOA
located in midbody IDA
IDA: 通过直接分析推断
19129479 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
17940959 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VPS37B 蛋白结构

Mod_r

Mod_r: Modifier of rudimentary (Mod(r)) protein (12 - 159)

  • 0
  • 100
  • 200
  • 285 a.a.
蛋白主名 其他名称

vacuolar protein sorting-associated protein 37B

ESCRT-I complex subunit VPS37B

VPS37B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra VPS37B Q9H9H4 QARS1 Homo sapiens P47897-2
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 QARS1 Homo sapiens P47897-2
Validated Y2H
25416956
Intra VPS37B Q9H9H4 VPS28 Homo sapiens Q548N1
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 VPS28 Homo sapiens Q548N1
Validated Y2H
25416956
Intra VPS37B Q9H9H4 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 PRKAA1 Homo sapiens Q13131
Validated Y2H
25416956
Intra VPS37B Q9H9H4 UBASH3B Homo sapiens Q8TF42
Validated Y2H
25416956
Intra VPS37B Q9H9H4 UBASH3B Homo sapiens Q8TF42
Y2H Array
25416956
Intra VPS37B Q9H9H4 TSG101 Homo sapiens Q99816
Anti Tag CoIP
35271311
Intra VPS37B Q9H9H4 BYSL Homo sapiens Q13895
Validated Y2H
25416956
Intra VPS37B Q9H9H4 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra VPS37B Q9H9H4 SMARCD1 Homo sapiens Q96GM5
Y2H
21516116
Intra VPS37B Q9H9H4 SMARCD1 Homo sapiens Q96GM5
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 NCK2 Homo sapiens O43639
Validated Y2H
25416956
Intra VPS37B Q9H9H4 NCK2 Homo sapiens O43639
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 NCK2 Homo sapiens O43639
Y2H Array
25416956
Intra VPS37B Q9H9H4 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
Intra VPS37B Q9H9H4 SH3YL1 Homo sapiens Q96HL8
Validated Y2H
25416956
Intra VPS37B Q9H9H4 SH3YL1 Homo sapiens Q96HL8
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 VPS28 Homo sapiens Q9UK41
Y2H
21516116
Intra VPS37B Q9H9H4 VPS28 Homo sapiens Q9UK41
Anti Tag CoIP
35271311
Intra VPS37B Q9H9H4 DCUN1D1 Homo sapiens Q96GG9
Validated Y2H
25416956
Intra VPS37B Q9H9H4 DCUN1D1 Homo sapiens Q96GG9
Y2H Array
25416956
Intra VPS37B Q9H9H4 DCUN1D1 Homo sapiens Q96GG9
Y2H Prey Pooling
25416956
Intra VPS37B Q9H9H4 SORBS3 Homo sapiens O60504
Y2H Array
25416956
Intra VPS37B Q9H9H4 ERCC1 Homo sapiens P07992
Validated Y2H
25416956
Intra VPS37B Q9H9H4 CDC73 Homo sapiens Q6P1J9
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15689 VPS37B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus VPS37B VGNC VGNC:107022
Rattus norvegicus VPS37B RGD RGD:1304576
Macaca mulatta VPS37B VGNC VGNC:100117
Mus musculus VPS37B MGD MGI:1916724
Felis catus VPS37B VGNC VGNC:107733
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z