NCK2 - NCK adaptor protein 2 Gene

中文名称：NCK 衔接蛋白 2

种属: Homo sapiens

同用名: GRB4; NCKbeta

关于 NCK2

功能概要

该基因编码 NCK 衔接蛋白家族的一个成员。该蛋白包含三个 SH3 结构域和一个 SH2 结构域。该蛋白质没有已知的催化功能，但已显示可结合和募集参与受体蛋白酪氨酸激酶调节的各种蛋白质。正是通过这些调节活动，该蛋白质被认为参与了细胞骨架重组。已经表征了编码不同亚型的替代转录剪接变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor Protein Tyrosine Kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]