FAM83A - family with sequence similarity 83 member A Gene

中文名称：具有序列相似性的家族 83 成员 A

种属: Homo sapiens

同用名: BJ-TSA-9

基因 ID: 84985 | 基因类型: protein coding

关于 FAM83A

This gene has 9 transcripts (splice variants), 161 orthologues and 7 paralogues. Biased expression in esophagus (RPKM 21.0), skin (RPKM 1.8) and 1 other tissue.

功能概要

实现相同的蛋白质结合活性；磷脂酰肌醇 3-激酶调节亚基结合活性；和蛋白激酶结合活性。参与细胞群增殖和表皮生长因子受体信号通路。预计位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity; phosphatidylinositol 3-kinase regulatory subunit binding activity; and protein kinase binding activity. Involved in cell population proliferation and epidermal growth factor receptor signaling pathway. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FAM83A 基因产物(5)

mRNA	Protein	Name
NM_001288587.3	NP_001275516.1	protein FAM83A isoform c
NM_001321630.2	NP_001308559.1	protein FAM83A isoform d
NM_001394396.1	NP_001381325.1	protein FAM83A isoform a
NM_032899.6	NP_116288.2	protein FAM83A isoform a
NM_207006.3	NP_996889.1	protein FAM83A isoform b

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA
enables phosphatidylinositol 3-kinase regulatory subunit binding	IDA IDA: 通过直接分析推断	22886303	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA
enables protein kinase binding	IDA IDA: 通过直接分析推断	22886303	GOA
enables protein kinase binding	IPI IPI: 通过物理相互作用推断	22886303	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cell population proliferation	IMP IMP: 通过突变表型推断	22886303	GOA
involved in epidermal growth factor receptor signaling pathway	IDA IDA: 通过直接分析推断	22886303	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FAM83A 蛋白结构

DUF1669

0
100
200
300
400
434 a.a.

蛋白主名

其他名称

protein FAM83A

tumor antigen BJ-TSA-9

FAM83A 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	FAM83A	Q86UY5	GPSM1	Homo sapiens	Q86YR5-3	Y2H Array	32296183
Intra	FAM83A	Q86UY5	GPSM1	Homo sapiens	Q86YR5-3	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	GPSM1	Homo sapiens	Q86YR5-3	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	KRTAP8-1	Homo sapiens	Q8IUC2	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PPP1R16B	Homo sapiens	Q96T49	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PPP1R16B	Homo sapiens	Q96T49	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	PPP1R16B	Homo sapiens	Q96T49	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	FAM83A	Q86UY5	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	FAM83A	Q86UY5	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	FOXI1	Homo sapiens	Q12951-2	Y2H Array	32296183
Intra	FAM83A	Q86UY5	FOXI1	Homo sapiens	Q12951-2	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	CSNK1E	Homo sapiens	P49674	Anti Tag CoIP	29789297
Intra	FAM83A	Q86UY5	ccsb orf id: 14249	Homo sapiens	EBI-22320186	Y2H Array	32296183
Intra	FAM83A	Q86UY5	CSNK1E	Homo sapiens	P49674	Anti Tag CoIP	33961781
Intra	FAM83A	Q86UY5	ccsb orf id: 14249	Homo sapiens	EBI-22320186	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	CSNK1E	Homo sapiens	P49674	Pull Down	29789297
Intra	FAM83A	Q86UY5	146664	Homo sapiens	EBI-10182452	Validated Y2H	25416956
Intra	FAM83A	Q86UY5	146664	Homo sapiens	EBI-10182452	Y2H Prey Pooling	25416956
Intra	FAM83A	Q86UY5	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	FAM83A	Q86UY5	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	FAM83A	Q86UY5	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	FAM83A	Q86UY5	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	FAM83A	Q86UY5	PLAGL2	Homo sapiens	Q9UPG8	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	PLAGL2	Homo sapiens	Q9UPG8	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	PLAGL2	Homo sapiens	Q9UPG8	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PSMA3	Homo sapiens	P25788	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PSMA3	Homo sapiens	P25788	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	FAM83A	Q86UY5	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	FAM83A	Q86UY5	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	FAM83A	Q86UY5	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	FAM83A	Q86UY5	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	FAM83A	Q86UY5	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	FAM83A	Q86UY5	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PRDM14	Homo sapiens	Q9GZV8	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	PRDM14	Homo sapiens	Q9GZV8	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	PRDM14	Homo sapiens	Q9GZV8	Y2H Array	32296183
Intra	FAM83A	Q86UY5	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	FAM83A	Q86UY5	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	FAM83A	Q86UY5	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	FAM83A	Q86UY5	BHLHE40	Homo sapiens	O14503	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	BHLHE40	Homo sapiens	O14503	Y2H Array	32296183
Intra	FAM83A	Q86UY5	MAGED1	Homo sapiens	Q9Y5V3	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	MAGED1	Homo sapiens	Q9Y5V3	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	MAGED1	Homo sapiens	Q9Y5V3	Y2H Array	32296183
Intra	FAM83A	Q86UY5	TRIM27	Homo sapiens	P14373	Validated Y2H	25416956
Intra	FAM83A	Q86UY5	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	FAM83A	Q86UY5	DAZAP2	Homo sapiens	Q15038	Y2H Array	32296183
Intra	FAM83A	Q86UY5	DAZAP2	Homo sapiens	Q15038	Y2H Prey Pooling	32296183
Intra	FAM83A	Q86UY5	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	FAM83A	Q86UY5	TRIM23	Homo sapiens	P36406	Validated Y2H	25416956
Intra	FAM83A	Q86UY5	UBQLN1	Homo sapiens	Q9UMX0	Y2H Pooling	32814053
Intra	FAM83A	Q86UY5	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32814053
Intra	FAM83A	Q86UY5	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32814053
Intra	FAM83A	Q86UY5	GCC1	Homo sapiens	Q96CN9	Validated Y2H	32296183
Intra	FAM83A	Q86UY5	SMYD1	Homo sapiens	Q8NB12	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Amelogenesis Imperfecta, Type Iiia

Ai3	Adhcai
Amelogenesis Imperfecta Type 3	AI3A
Amelogenesis Imperfecta, Type Iii	Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Dominant
Amelogenesis Imperfecta Type 3a	Amelogenesis Imperfecta Hypomineralization Type
Amelogenesis Imperfecta Type Iii	Hypocalcified Amelogenesis Imperfecta
Amelogenesis Imperfecta, Type 3	Amelogenesis Imperfecta, Hypomineralization Type
Autosomal Dominant Amelogenesis Imperfecta Hypocalcification Type	Amelogenesis Imperfecta 3a
Amelogenesis Imperfecta Hypocalcification Type Autosomal Dominant

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS04721	FAM83A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	FAM83A	VGNC	VGNC:72384
Canis familiaris	FAM83A	VGNC	VGNC:40699
Bos taurus	FAM83A	VGNC	VGNC:28832
Rattus norvegicus	FAM83A	RGD	RGD:1565606
Mus musculus	FAM83A	MGD	MGI:2447773
Felis catus	FAM83A	VGNC	VGNC:81657

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4