2. Gene
  3. SMYD1 - SET and MYND domain containing 1 Gene

SMYD1 - SET and MYND domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 SET 和 MYND 域 1

种属: Homo sapiens

同用名: BOP; KMT3D; ZMYND18; ZMYND22

基因 ID: 150572 | 基因类型: protein coding

关于 SMYD1

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:88,067,825-88,113,384 (from NCBI)

This gene has 4 transcripts (splice variants), 287 orthologues and 5 paralogues. Restricted expression toward heart (RPKM 63.9).

功能概要

预测可启用组蛋白-赖氨酸 N-甲基转移酶活性。参与成肌细胞分化的正调控和肌管分化的正调控。预计位于细胞质中。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable histone-lysine N-methyltransferase activity. Involved in positive regulation of myoblast differentiation and positive regulation of myotube differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SMYD1 基因产物(2)

mRNA Protein Name
NM_001330364.2 NP_001317293.1 histone-lysine N-methyltransferase SMYD1 isoform 2
NM_198274.4 NP_938015.1 histone-lysine N-methyltransferase SMYD1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23455924 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of myoblast differentiation IDA
IDA: 通过直接分析推断
19783823 GOA
involved in positive regulation of myotube differentiation IDA
IDA: 通过直接分析推断
19783823 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SMYD1 蛋白结构

SET

SET: SET domain (18 - 252)

zf-MYND

zf-MYND: MYND finger (52 - 90)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 490 a.a.
蛋白主名 其他名称

histone-lysine N-methyltransferase SMYD1

CD8 beta opposite

SMYD1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SMYD1 Q8NB12 HOMEZ Homo sapiens Q8IX15-3
Validated Y2H
25416956
种属内
SMYD1 Q8NB12 DVL1 Homo sapiens Q86TH3
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 DVL1 Homo sapiens Q86TH3
Y2H Array
32296183
种属内
SMYD1 Q8NB12 SNX11 Homo sapiens Q9Y5W9
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 SNX11 Homo sapiens Q9Y5W9
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 SNX11 Homo sapiens Q9Y5W9
Y2H Array
32296183
种属内
SMYD1 Q8NB12 ADSS2 Homo sapiens P30520
TAP
24981860
种属内
SMYD1 Q8NB12 ADSS2 Homo sapiens P30520
Anti Tag CoIP
33961781
种属内
SMYD1 Q8NB12 ADSS2 Homo sapiens P30520
Anti Tag CoIP
28514442
种属内
SMYD1 Q8NB12 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 KRT35 Homo sapiens Q92764
Y2H Array
32296183
种属内
SMYD1 Q8NB12 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 KIF16B Homo sapiens Q96L93-6
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 KIF16B Homo sapiens Q96L93-6
Y2H Array
32296183
种属内
SMYD1 Q8NB12 KIF16B Homo sapiens Q96L93-6
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 PATZ1 Homo sapiens Q9HBE1-4
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 PATZ1 Homo sapiens Q9HBE1-4
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 PATZ1 Homo sapiens Q9HBE1-4
Y2H Array
32296183
种属内
SMYD1 Q8NB12 SPAG8 Homo sapiens Q99932-2
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 SPAG8 Homo sapiens Q99932-2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 SPAG8 Homo sapiens Q99932-2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
种属内
SMYD1 Q8NB12 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 POU6F2 Homo sapiens P78424
Y2H Array
32296183
种属内
SMYD1 Q8NB12 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 RSPH6A Homo sapiens Q9H0K4
Y2H Array
32296183
种属内
SMYD1 Q8NB12 RSPH6A Homo sapiens Q9H0K4
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 RSPH6A Homo sapiens Q9H0K4
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 CIMIP2A Homo sapiens Q6J272
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 CIMIP2A Homo sapiens Q6J272
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MYH7B Homo sapiens A7E2Y1-2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MYH7B Homo sapiens A7E2Y1-2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 FAM86C1P Homo sapiens Q9NVL1-2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 FAM86C1P Homo sapiens Q9NVL1-2
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 FAM86C1P Homo sapiens Q9NVL1-2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 FAM83A Homo sapiens Q86UY5
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 FAM83A Homo sapiens Q86UY5
Y2H Array
32296183
种属内
SMYD1 Q8NB12 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 TBRG1 Homo sapiens Q3YBR2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 TBRG1 Homo sapiens Q3YBR2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MYH7B Homo sapiens A7E2Y1
Y2H
23455924
种属内
SMYD1 Q8NB12 UTP14A Homo sapiens Q9BVJ6
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 UTP14A Homo sapiens Q9BVJ6
Y2H Array
32296183
种属内
SMYD1 Q8NB12 UTP14A Homo sapiens Q9BVJ6
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 NEFL Homo sapiens P07196
Y2H Array
32296183
种属内
SMYD1 Q8NB12 NEFL Homo sapiens P07196
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 ZBTB44 Homo sapiens Q8NCP5
Validated Y2H
25416956
种属内
SMYD1 Q8NB12 ZBTB44 Homo sapiens Q8NCP5
Y2H Prey Pooling
25416956
种属内
SMYD1 Q8NB12 RUSC1 Homo sapiens Q9BVN2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 RUSC1 Homo sapiens Q9BVN2
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 RUSC1 Homo sapiens Q9BVN2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 BHLHE40 Homo sapiens O14503
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 BHLHE40 Homo sapiens O14503
Y2H Array
32296183
种属内
SMYD1 Q8NB12 CFAP68 Homo sapiens Q9H5F2
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 CFAP68 Homo sapiens Q9H5F2
Y2H Array
32296183
种属内
SMYD1 Q8NB12 CFAP68 Homo sapiens Q9H5F2
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 ZBTB3 Homo sapiens Q9H5J0
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 ZBTB3 Homo sapiens Q9H5J0
Y2H Array
32296183
种属内
SMYD1 Q8NB12 ZBTB3 Homo sapiens Q9H5J0
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 MDFI Homo sapiens Q99750
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 MDFI Homo sapiens Q99750
Y2H Array
32296183
种属内
SMYD1 Q8NB12 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 HMG20A Homo sapiens Q9NP66
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 HMG20A Homo sapiens Q9NP66
Y2H Array
32296183
种属内
SMYD1 Q8NB12 HMG20A Homo sapiens Q9NP66
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 HDHD3 Homo sapiens Q9BSH5
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 HDHD3 Homo sapiens Q9BSH5
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 HDHD3 Homo sapiens Q9BSH5
Y2H Array
32296183
种属内
SMYD1 Q8NB12 FAM204A Homo sapiens Q9H8W3
Validated Y2H
32296183
种属内
SMYD1 Q8NB12 FAM204A Homo sapiens Q9H8W3
Y2H Prey Pooling
32296183
种属内
SMYD1 Q8NB12 FAM204A Homo sapiens Q9H8W3
Y2H Array
32296183
种属内
SMYD1 Q8NB12 ARID5A Homo sapiens Q03989
Y2H Array
32296183
种属内
SMYD1 Q8NB12 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

SMYD1 抗体

目录号 产品名 应用 反应物种
HY-P80895 SMYD1 Antibody (YA672) WB Rat

关联疾病

疾病名称 别名
Distal Muscular Dystrophy With Anterior Tibial Onset

Dmat
Epiphyseal Dysplasia, Multiple, 1

EDM1

Multiple Epiphyseal Dysplasia 1

Multiple Epiphyseal Dysplasia Type 1

Med1

Multiple Epiphyseal Dysplasia Comp-Related

Polyepiphyseal Dysplasia Type 1

Multiple Epiphyseal Dysplasia, Comp-Related

Epiphyseal Dysplasia Multiple 1

Epiphyseal Dysplasia, Multiple 1

Dysplasia, Epiphyseal, Multiple, Type 1
Tetralogy Of Fallot

TOF

Fallot Tetralogy

Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

Tetrad Of Fallot

Fallot Tetrad

Fallot Disease

Fallot Complex

Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

Interventricular Septal Defect, In Tetralogy Of Fallot

Ventricular Septal Defect With Obstructed Right Ventricular Outflow

Tof - [Tetralogy Of Fallot]

Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

Pulmonary Atresia, Ventricular Septal Defect And Mapcas

Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13461 SMYD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SMYD1 VGNC VGNC:46581
Bos taurus SMYD1 VGNC VGNC:35042
Macaca mulatta SMYD1 VGNC VGNC:77751
Rattus norvegicus SMYD1 RGD RGD:1305105
Felis catus SMYD1 VGNC VGNC:81223
Mus musculus SMYD1 MGD MGI:104790
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