BACH2 - BTB domain and CNC homolog 2 Gene

中文名称：BTB 域和 CNC 同系物 2

种属: Homo sapiens

同用名: IMD60; BTBD25

基因 ID: 60468 | 基因类型: protein coding

关于 BACH2

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,926,528-90,296,843 (from NCBI)

This gene has 13 transcripts (splice variants), 207 orthologues, 54 paralogues and is associated with 1 phenotype. Biased expression in lymph node (RPKM 7.1), appendix (RPKM 2.5) and 10 other tissues.

功能概要

启用序列特异性双链 DNA 结合活性。参与涉及 T 细胞和 B 细胞的初级适应性免疫反应。位于细胞质和核质中。与免疫缺陷 60 有关。[由基因组资源联盟提供，2022 年 4 月]

Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Implicated in immunodeficiency 60. [provided by Alliance of Genome Resources, Apr 2022]

BACH2 基因产物(2)

mRNA	Protein	Name
NM_001170794.2	NP_001164265.1	transcription regulator protein BACH2
NM_021813.4	NP_068585.1	transcription regulator protein BACH2

BACH2 蛋白结构

BTB

bZIP_Maf

0
200
400
600
841 a.a.

蛋白主名

其他名称

transcription regulator protein BACH2

BTB and CNC homolog 2

BACH2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	BACH2	Q9BYV9	LUZP4	Homo sapiens	Q9P127	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	BATF3	Homo sapiens	Q9NR55	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	TSHZ2	Homo sapiens	Q9NRE2	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	MAFK	Homo sapiens	O60675	Anti Tag CoIP	33961781
Intra	BACH2	Q9BYV9	NXF1	Homo sapiens	Q9UBU9	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	CBX8	Homo sapiens	Q9HC52	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	MAFG	Homo sapiens	O15525	FRET	23661758
Intra	BACH2	Q9BYV9	MAFG	Homo sapiens	O15525	Anti Tag CoIP	33961781
Intra	BACH2	Q9BYV9	MAFF	Homo sapiens	Q9ULX9	FRET	23661758
Intra	BACH2	Q9BYV9	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	CTSZ	Homo sapiens	Q9UBR2	Validated Y2H	32296183
Intra	BACH2	Q9BYV9	MLX	Homo sapiens	Q9UH92-3	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Immunodeficiency 60 And Autoimmunity

Immunodeficiency And Autoimmunity, Bach2-Related	IMD60
Brida	Immunodeficiency 60

Immunodeficiency 60

Bach2-Related Immunodeficiency And Autoimmunity	Brida
Imd60

Immunodeficiency 58

IMD58	Severe Combined Immunodeficiency Due To Carmil2 Deficiency
Combined Immunodeficiency Due To Carmil2 Deficiency	Combined Immunodeficiency Due To Rltpr Deficiency

Burkitt Lymphoma

Burkitt'S Lymphoma	BL
Burkitt Lymphoma, Somatic	Burkitt Lymphoma/Leukaemia
Burkitt'S Tumor	Burkitt'S Tumor Or Lymphoma
Malignant Lymphoma, Burkitt'S Type	Small Non-Cleaved Cell Lymphoma, Burkitt'S Type
Small Non-Cleaved Cell Lymphoma	Burkitt Tumor
Burkitts Lymphoma	Lymphoma, Small Noncleaved-Cell
Burkitt Tumour	Diffuse Small Noncleaved Malignant Burkitt Lymphoma
Malignant Burkitt Lymphoma	“Burkitt-Like” Lymphoma
Undifferentiated Burkitt Lymphoma	Small Noncleaved Cell Burkitt Lymphoma

Leukemia, Chronic Myeloid

Chronic Myeloid Leukemia	Chronic Myelogenous Leukemia
CML	Chronic Granulocytic Leukemia
Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib	Chronic Myeloid Leukaemia
Chronic Granulocytic Leukaemia	Chronic Myelogenous Leukaemia
Myeloid Leukemia, Chronic	Leukemia, Chronic Myelogenous
Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic	Cml - Chronic Myelogenous Leukemia
Cgl	Chronic Myelocytic Leukemia
Leukemia, Chronic Myeloid, Atypical	ACML
Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative	Myeloid Leukemia Chronic
Leukemia, Myeloid, Chronic	Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative
Cml- [Chronic Myeloid Leukaemia]	Cgl - [Chronic Granulocytic Leukaemia]
Chronic Myelocytic Leukaemia

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma	Lymphoma, Non-Hodgkin
NHL	Lymphoma, Non-Hodgkin, Somatic
Lymphoma, Follicular, Somatic	Familial Non-Hodgkin Lymphoma
Lymphoma Non-Hodgkins	Follicular Lymphoma, Somatic
Lymphosarcoma	Non-Hodgkins Lymphoma

Celiac Disease 1

Celiac Disease	Coeliac Disease
Celiac Sprue	Celiac Disease, Susceptibility To
Gluten-Sensitive Enteropathy	Nontropical Sprue
Sprue	CELIAC1
Celiac Disease, Susceptibility To, 1	Celiac Sprue 1
Celiac Sprue, Susceptibility To, 1	Gluten-Sensitive Enteropathy 1
Gluten-Sensitive Enteropathy, Susceptibility To, 1	Idiopathic Steatorrhea
Cœliac Disease	Gluten Intolerance
Gluten-Induced Enteropathy	Gluten Enteropathy
Celiac Disease, Susceptibility To, Type 1	Childhood Celiac Disease
Coeliac Rickets	Gee Disease
Gee-Herter Disease	Heubner-Herter Disease
Idiopathic Steatorrhoea	Thaysen'S Disease
Herter Gee Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01340	BACH2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	BACH2	MGD	MGI:894679
Bos taurus	BACH2	VGNC	VGNC:26403
Macaca mulatta	BACH2	VGNC	VGNC:70069
Canis familiaris	BACH2	VGNC	VGNC:38361
Rattus norvegicus	BACH2	RGD	RGD:1562865
Felis catus	BACH2	VGNC	VGNC:60068
Others	BACH2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

BACH2 - BTB domain and CNC homolog 2 Gene

关于 BACH2

功能概要

BACH2 基因产物(2)

BACH2 蛋白结构

BACH2 蛋白互作信息

关联疾病

直系同源

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BACH2 - BTB domain and CNC homolog 2 Gene

关于 BACH2

功能概要

BACH2 基因产物(2)

BACH2 蛋白结构

BACH2 蛋白互作信息

关联疾病

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直系同源

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