1. Gene
  2. PLAGL2 - PLAG1 like zinc finger 2 Gene

PLAGL2 - PLAG1 like zinc finger 2 Gene

中文名称:PLAG1 样锌指 2

种属: Homo sapiens

同用名: ZNF900

基因 ID: 5326 | 基因类型: protein coding

关于 PLAGL2

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:32,192,504-32,207,743 (from NCBI)

This gene has 1 transcript (splice variant), 285 orthologues and 29 paralogues. Broad expression in bone marrow (RPKM 10.2), testis (RPKM 9.3) and 25 other tissues.

功能概要

多形性腺瘤基因样 2 是一种识别 DNA 和/或 RNA 的锌指蛋白。[RefSeq 提供,2008 年 7 月]

Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. [provided by RefSeq, Jul 2008]

PLAGL2 基因产物(1)

mRNA Protein Name
NM_002657.3 NP_002648.1 zinc finger protein PLAGL2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15361364 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15361364 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PLAGL2 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (85 - 108)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (128 - 149)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (170 - 202)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (219 - 242)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 496 a.a.
蛋白主名 其他名称

zinc finger protein PLAGL2

C2H2-type zinc finger protein

PLAGL2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PLAGL2 Q9UPG8 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pleomorphic Adenoma

Mixed Tumor Of The Salivary Gland

Adenoma Pleomorphic

Adenoma, Pleomorphic

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Adenoma

Acinar Cell Adenoma

Adenomas

Acinic Cell Adenoma

Cataract 30

Cataract 30 Pulverulent

Cataract Coppock-Like

Ctrct30

Dusty Cataract

Cataract, Type 30

Gastrointestinal System Benign Neoplasm
Developmental And Epileptic Encephalopathy 1

Epileptic Encephalopathy, Early Infantile, 1

Infantile Epileptic-Dyskinetic Encephalopathy

DEE1

Eiee1

Issx1

Xmesid

X-Linked Infantile Spasm Syndrome 1

X-Linked Infantile Spasm Syndrome

X-Linked Spasticity-Intellectual Disability-Epilepsy Syndrome

Developmental And Epileptic Encephalopathy, 1

Infantile Epileptic Dyskinetic Encephalopathy

Infantile Spasm Syndrome, X-Linked 1

West Syndrome, X-Linked

Ohtahara Syndrome, X-Linked

Early Infantile Epileptic Encephalopathy 1

Early Infantile Epileptic Encephalopathy-1

Issx

X-Linked Ohtahara Syndrome

X-Linked West Syndrome

Infantile Spasm Syndrome X-Linked 1

Myoclonic Epilepsy X-Linked With Intellectual Disability And Spasticity

Ohtahara Syndrome X-Linked

West Syndrome X-Linked

Encephalopathy, Epileptic, Early Infantile, Type 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus PLAGL2 VGNC VGNC:68889
Macaca mulatta PLAGL2 VGNC VGNC:76160
Canis familiaris PLAGL2 VGNC VGNC:44640
Bos taurus PLAGL2 VGNC VGNC:32973
Rattus norvegicus PLAGL2 RGD RGD:1307999
Mus musculus PLAGL2 MGD MGI:1933165