GCC1 - GRIP and coiled-coil domain containing 1 Gene

中文名称：含 GRIP 和卷曲卷曲结构域 1

种属: Homo sapiens

同用名: GCC1P; GCC88

基因 ID: 79571 | 基因类型: protein coding

关于 GCC1

Cytogenetic location: 7q32.1 Genomic coordinates (GRCh38): 7:127,580,628-127,585,596 (from NCBI)

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 9.0), bone marrow (RPKM 5.7) and 25 other tissues.

功能概要

该基因编码的蛋白质是外周膜蛋白。它对 brefeldin A 敏感。这种编码的蛋白质包含一个 GRIP 结构域，该结构域被认为可用于靶向。它可能在参与膜运输的跨高尔基体网络亚室的组织中发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]

GCC1 基因产物(1)

mRNA	Protein	Name
NM_024523.6	NP_078799.2	GRIP and coiled-coil domain-containing protein 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GCC1 蛋白结构

GRIP

0
200
400
600
775 a.a.

蛋白主名

其他名称

GRIP and coiled-coil domain-containing protein 1

golgi coiled-coil 1

GCC1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	GCC1	Q96CN9	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	32296183
Intra	GCC1	Q96CN9	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	MID2	Homo sapiens	Q9UJV3-2	Y2H Array	32296183
Intra	GCC1	Q96CN9	NECAB2	Homo sapiens	Q7Z6G3-2	Y2H Array	25416956
Intra	GCC1	Q96CN9	ZNF276	Homo sapiens	Q8N554-2	Y2H Array	25416956
Intra	GCC1	Q96CN9	NAV1	Homo sapiens	Q8NEY1-4	Y2H Array	25416956
Intra	GCC1	Q96CN9	NAV1	Homo sapiens	Q8NEY1-4	Validated Y2H	25416956
Intra	GCC1	Q96CN9	NAV1	Homo sapiens	Q8NEY1-4	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	HDX	Homo sapiens	Q7Z353	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	HDX	Homo sapiens	Q7Z353	Y2H Array	32296183
Intra	GCC1	Q96CN9	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	25416956
Intra	GCC1	Q96CN9	ZFP90	Homo sapiens	Q8TF47	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	ZFP90	Homo sapiens	Q8TF47	Y2H Array	32296183
Intra	GCC1	Q96CN9	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	GCC1	Q96CN9	TP53BP2	Homo sapiens	Q05BL1	Y2H Array	32296183
Intra	GCC1	Q96CN9	TP53BP2	Homo sapiens	Q05BL1	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	DISC1	Homo sapiens	Q9NRI5-2	Validated Y2H	32296183
Intra	GCC1	Q96CN9	DISC1	Homo sapiens	Q9NRI5-2	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	DISC1	Homo sapiens	Q9NRI5-2	Y2H Array	32296183
Intra	GCC1	Q96CN9	RUNX1	Homo sapiens	Q01196-8	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	RUNX1	Homo sapiens	Q01196-8	Y2H Array	32296183
Intra	GCC1	Q96CN9	ICA1L	Homo sapiens	Q8NDH6-2	Y2H Array	32296183
Intra	GCC1	Q96CN9	ICA1L	Homo sapiens	Q8NDH6-2	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	FAM83A	Homo sapiens	Q86UY5	Y2H Array	32296183
Intra	GCC1	Q96CN9	FAM83A	Homo sapiens	Q86UY5	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	PRPF18	Homo sapiens	Q99633	Validated Y2H	32296183
Intra	GCC1	Q96CN9	KIAA0753	Homo sapiens	Q2KHM9	Validated Y2H	25416956
Intra	GCC1	Q96CN9	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	MEOX1	Homo sapiens	P50221	Y2H Array	32296183
Intra	GCC1	Q96CN9	CEP57	Homo sapiens	Q86XR8	Y2H Array	25416956
Intra	GCC1	Q96CN9	CEP57	Homo sapiens	Q86XR8	Y2H	21516116
Intra	GCC1	Q96CN9	MCRS1	Homo sapiens	Q96EZ8	Y2H Pooling	19060904
Intra	GCC1	Q96CN9	MCRS1	Homo sapiens	Q96EZ8	Y2H Array	19060904
Intra	GCC1	Q96CN9	MED4	Homo sapiens	Q9NPJ6	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	MED4	Homo sapiens	Q9NPJ6	Validated Y2H	32296183
Intra	GCC1	Q96CN9	MED4	Homo sapiens	Q9NPJ6	Y2H Array	32296183
Intra	GCC1	Q96CN9	DNAJA3	Homo sapiens	Q96EY1-2	Y2H Array	25416956
Intra	GCC1	Q96CN9	ATF4	Homo sapiens	P18848	Y2H Array	32296183
Intra	GCC1	Q96CN9	ATF4	Homo sapiens	P18848	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	ATF4	Homo sapiens	P18848	Y2H Array	25416956
Intra	GCC1	Q96CN9	BIRC2	Homo sapiens	Q13490	Y2H Array	32296183
Intra	GCC1	Q96CN9	BIRC2	Homo sapiens	Q13490	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	XIAP	Homo sapiens	P98170	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	XIAP	Homo sapiens	P98170	Y2H Array	32296183
Intra	GCC1	Q96CN9	PPP1R27	Homo sapiens	Q86WC6	Y2H Array	32296183
Intra	GCC1	Q96CN9	PPP1R27	Homo sapiens	Q86WC6	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	OIP5	Homo sapiens	O43482	Validated Y2H	25416956
Intra	GCC1	Q96CN9	OIP5	Homo sapiens	O43482	Y2H Array	25416956
Intra	GCC1	Q96CN9	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	GCC1	Q96CN9	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	GCC1	Q96CN9	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	LCA5	Homo sapiens	Q86VQ0	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	LCA5	Homo sapiens	Q86VQ0	Y2H Array	32296183
Intra	GCC1	Q96CN9	TRIM29	Homo sapiens	Q14134	Pull Down	16189514
Intra	GCC1	Q96CN9	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	25416956
Intra	GCC1	Q96CN9	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	32296183
Intra	GCC1	Q96CN9	FBXO28	Homo sapiens	Q9NVF7	Validated Y2H	32296183
Intra	GCC1	Q96CN9	LZTS2	Homo sapiens	Q9BRK4	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	PAK5	Homo sapiens	Q9P286	Y2H Array	25416956
Intra	GCC1	Q96CN9	PAK5	Homo sapiens	Q9P286	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	KATNAL1	Homo sapiens	Q9BW62	Validated Y2H	32296183
Intra	GCC1	Q96CN9	KATNAL1	Homo sapiens	Q9BW62	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	KATNAL1	Homo sapiens	Q9BW62	Y2H Array	32296183
Intra	GCC1	Q96CN9	ABI2	Homo sapiens	Q9NYB9	Y2H Prey Pooling	25416956
Intra	GCC1	Q96CN9	ABI2	Homo sapiens	Q9NYB9	Y2H Array	29892012
Intra	GCC1	Q96CN9	ABI2	Homo sapiens	Q9NYB9	Validated Y2H	25416956
Intra	GCC1	Q96CN9	FOSL1	Homo sapiens	P15407	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	FOSL1	Homo sapiens	P15407	Y2H Array	32296183
Intra	GCC1	Q96CN9	ZC4H2	Homo sapiens	Q9NQZ6	Validated Y2H	32296183
Intra	GCC1	Q96CN9	ZC4H2	Homo sapiens	Q9NQZ6	Y2H Array	32296183
Intra	GCC1	Q96CN9	ZC4H2	Homo sapiens	Q9NQZ6	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	FIGNL1	Homo sapiens	Q6PIW4	Y2H Array	32296183
Intra	GCC1	Q96CN9	FIGNL1	Homo sapiens	Q6PIW4	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	NAB2	Homo sapiens	Q15742	Y2H Array	25416956
Intra	GCC1	Q96CN9	NAB2	Homo sapiens	Q15742	Validated Y2H	25416956
Intra	GCC1	Q96CN9	C1orf94	Homo sapiens	Q6P1W5	Y2H Array	25416956
Intra	GCC1	Q96CN9	TRIM50	Homo sapiens	Q86XT4	Y2H Prey Pooling	32296183
Intra	GCC1	Q96CN9	TRIM50	Homo sapiens	Q86XT4	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Charcot-Marie-Tooth Disease, Axonal, Type 2z

CMT2Z	Charcot-Marie-Tooth Disease Axonal Type 2z
Charcot-Marie-Tooth Disease, Axonal, Autosomal Dominant, Type 2z	Charcot-Marie-Tooth Neuropathy, Type 2z
Autosomal Dominant Axonal Charcot-Marie-Tooth Disease Type 2z	Charcot-Marie-Tooth Neuropathy Type 2z
Autosomal Dominant Charcot-Marie-Tooth Disease Type 2z	Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 Due To Morc2 Mutation
Charcot-Marie-Tooth Disease 2z	Charcot-Marie-Tooth Disease, Type 2z

Phencyclidine Abuse

Pcp Abuse

Maturity-Onset Diabetes Of The Young

MODY	Maturity Onset Diabetes Mellitus In Young
Mason-Type Diabetes	Mason Type Diabetes
Maturity Onset Diabetes Of The Young	Mody Syndrome
Diabetes Of The Young, Maturity-Onset

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05319	GCC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	GCC1	VGNC	VGNC:41139
Bos taurus	GCC1	VGNC	VGNC:29280
Rattus norvegicus	GCC1	RGD	RGD:2319954
Felis catus	GCC1	VGNC	VGNC:62487
Mus musculus	GCC1	MGD	MGI:1921625
Macaca mulatta	GCC1	VGNC	VGNC:72742

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4